Tyrphostin B48

DB16774ExperimentalSmall molecule

Tyrphostin B48: Overview.

Mechanism: Pharmacologically active on Epidermal growth factor receptor
Curator reviewed
Formula / weight: C₁₆H₁₂N₂O₃ · 280.283 g/mol (avg)
Also known as: AG 494 · AG-494 · Alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide · Tyrphostin AG-494

Resolves to

Compound

Structure

InChIKeyHKHOVJYOELRGMV-XYOKQWHBSA-NSMILESOC1=CC=C(\C=C(/C#N)C(=O)NC2=CC=CC=C2)C=C1O

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tyrphostin B48, and which of those have an active Phase 3 trial?

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