Displaying drugs 1126 - 1150 of 1168 in total
4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE
Experimental
Matched Name: … 4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL) …
Matched Iupac: … 4-[(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazine-1-carbonyl]benzonitrile …
Matched Iupac: … 4-[(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazine-1-carbonyl]benzonitrile …
2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Experimental
Matched Name: … 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC …
Matched Iupac: … (4S)-2-[(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl]-5-methylidene-5,6-dihydro-4H-1,3-thiazine-4-carboxylic …
Matched Iupac: … (4S)-2-[(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl]-5-methylidene-5,6-dihydro-4H-1,3-thiazine-4-carboxylic …
Candesartan cilexetil
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Iupac: … 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl …
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Zinda-candesartan/hydrochlorothiazide ... Zinda-candesartan/hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Zinda-candesartan …
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Zinda-candesartan/hydrochlorothiazide ... Zinda-candesartan/hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Zinda-candesartan …
4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE
Experimental
Matched Name: … 4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE …
Matched Iupac: … 5-chloro-2-{[(3R)-3-(2-methylpropyl)-4-[5-(pyridin-4-yl)pyrimidine-2-carbonyl]piperazin-1-yl]sulfonyl …
Matched Iupac: … 5-chloro-2-{[(3R)-3-(2-methylpropyl)-4-[5-(pyridin-4-yl)pyrimidine-2-carbonyl]piperazin-1-yl]sulfonyl …
Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide
Experimental
Matched Name: … Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl …
Matched Iupac: … [(1S)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl][(2S)-2-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl] …
Matched Iupac: … [(1S)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl][(2S)-2-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl] …
TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE
Experimental
Matched Name: … TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1- …
N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide
Experimental
Matched Name: … N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide …
Matched Iupac: … N-{4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]phenyl}-4-(morpholin-4-yl)-4-oxobutanamide …
Matched Iupac: … N-{4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]phenyl}-4-(morpholin-4-yl)-4-oxobutanamide …
2-[(1R)-2-carboxy-1-(naphthalen-1-ylmethyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
Experimental
Matched Name: … 2-[(1R)-2-carboxy-1-(naphthalen-1-ylmethyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
Matched Iupac: … 2-[(2R)-1-carboxy-3-(naphthalen-1-yl)propan-2-yl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
Matched Iupac: … 2-[(2R)-1-carboxy-3-(naphthalen-1-yl)propan-2-yl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
H3B-6527
H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).
Investigational
Matched Synonyms: … 2-PROPENAMIDE, N-(2-((6-((((2,6-DICHLORO-3,5-DIMETHOXYPHENYL)AMINO)CARBONYL)METHYLAMINO)-4-PYRIMIDINYL …
2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Experimental
Matched Name: … 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic …
Matched Iupac: … [(1R)-2-(3-{methyl[1-(naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl}naphthalen-2-yl)-1-(naphthalen- …
Matched Iupac: … [(1R)-2-(3-{methyl[1-(naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl}naphthalen-2-yl)-1-(naphthalen- …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … Wap four-disulfide core domain protein 4 …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and ... zinc chloride fractionation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and ... zinc chloride fractionation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE
Experimental
Matched Name: … 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE …
Matched Iupac: … 2-{4-[(5-chloro-1H-indol-2-yl)sulfonyl]piperazine-1-carbonyl}thieno[3,2-b]pyridin-4-ium-4-olate …
Matched Iupac: … 2-{4-[(5-chloro-1H-indol-2-yl)sulfonyl]piperazine-1-carbonyl}thieno[3,2-b]pyridin-4-ium-4-olate …
Cefoperazone
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1- …
Matched Iupac: … (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Iupac: … (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
SB 224289
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Synonyms: … 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro ... piperidine), 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)(1,1'-biphenyl)-4-yl)carbonyl …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
Anvatabart opadotin
Investigational
Matched Synonyms: … anti-(human epidermal growth factor receptor HER2) (human-Mus musculus monoclonal Amab788 γ1-chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA. …
Matched Iupac: … carboxybutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … carboxybutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Etoposide toniribate
Investigational
Matched Synonyms: … Carbonic acid, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-((5r,5ar,8ar,9s)-9-((4,6-o-(1r)-ethylidene-.beta …
Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate
Experimental
Matched Name: … Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy …
Matched Iupac: … [(1R)-1-[(2S)-6-azaniumyl-2-{[(2S)-1-[(benzyloxy)carbonyl]pyrrolidin-2-yl]formamido}hexanamido]-2-phenylethyl …
Matched Iupac: … [(1R)-1-[(2S)-6-azaniumyl-2-{[(2S)-1-[(benzyloxy)carbonyl]pyrrolidin-2-yl]formamido}hexanamido]-2-phenylethyl …
2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL
Experimental
Matched Name: … 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE …
Matched Iupac: … 2,2,2-trifluoro-1-(5-{3-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-7-carbonyl}thiophen-2-yl)ethane-1,1 …
Matched Iupac: … 2,2,2-trifluoro-1-(5-{3-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-7-carbonyl}thiophen-2-yl)ethane-1,1 …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one …
(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE
Experimental
Matched Name: … (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO …
Palopegteriparatide
Palopegteriparatide is a mPEG conjugated parathyroid hormone 1-34.
Investigational
Matched Synonyms: … 2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl …
(2S)-2-amino-6-[[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl]amino]-6-oxohexanoic acid
Experimental
Matched Name: … (2S)-2-amino-6-[[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methylsulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Matched Iupac: … (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
Matched Iupac: … (2S)-2-amino-5-{[(3R,4R)-1-[(1S)-1-carboxy-2-[(S)-methanesulfinyl]ethyl]-2-oxo-4-sulfanylazetidin-3-yl …
N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid
Experimental
Matched Name: … 4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl …
Potassium (Benzenesulfonyl)({[6-(3-{2-[1-(Trifluoromethyl)Cyclopropyl]Ethoxy}-1H-Pyrazol-1-Yl)-2-[(4S)-2,2,4-Trimethylpyrrolidin-1-Yl]Pyridin-3-Yl]Carbonyl})Azanide
Investigational
Matched Name: … Trifluoromethyl)Cyclopropyl]Ethoxy}-1H-Pyrazol-1-Yl)-2-[(4S)-2,2,4-Trimethylpyrrolidin-1-Yl]Pyridin-3-Yl]Carbonyl …
Displaying drugs 1126 - 1150 of 1168 in total