Displaying drugs 1126 - 1150 of 2186 in total
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ... (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … N-methyl-2-pyridineethanamine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Synonyms: … 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ... 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine ... 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol …
Matched Iupac: … 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Iupac: … 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Rolitetracycline
A pyrrolidinylmethyl tetracycline.
Approved
Matched Synonyms: … Pyrrolidino-methyl-tetracycline …
Matched Iupac: … 1-yl)methyl]-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin- …
Matched Iupac: … 1-yl)methyl]-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin- …
6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile
Experimental
Matched Synonyms: … 6-(Cyclohexylamino)-9-[2-(4-methyl-1-piperazinyl)ethyl]-9H-purine-2-carbonitrile …
AZD-1940
Investigational
Matched Synonyms: … Ethanesulfonamide, n-(1-((4,4-difluorocyclohexyl)methyl)-2-(1,1-dimethylethyl)-1h-benzimidazol-5-yl)- …
Matched Iupac: … N-{2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-1,3-benzodiazol-5-yl}ethane-1-sulfonamide …
Matched Iupac: … N-{2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-1,3-benzodiazol-5-yl}ethane-1-sulfonamide …
Umeclidinium
Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less...
Approved
Matched Synonyms: … 1-[2-(benzyloxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane …
Matched Description: … progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and ... fluticasone furoate] under the brand name ANORO ELLIPTA and TRELEGY ELLIPTA respectively. ... [A7719] By blocking the M3 muscarinic receptor, umeclidinium inhibits the binding of acetylcholine and …
Matched Categories: … vilanterol and umeclidinium bromide ... vilanterol, umeclidinium bromide and fluticasone furoate …
Matched Description: … progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and ... fluticasone furoate] under the brand name ANORO ELLIPTA and TRELEGY ELLIPTA respectively. ... [A7719] By blocking the M3 muscarinic receptor, umeclidinium inhibits the binding of acetylcholine and …
Matched Categories: … vilanterol and umeclidinium bromide ... vilanterol, umeclidinium bromide and fluticasone furoate …
Alminoprofen
Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
Experimental
Matched Synonyms: … α-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
CT-179
Investigational
Matched Synonyms: … 1-(2-(3-(3,4-dichlorophenyl)ureido)-6-methyl-pyrimidin-4-yl)-amino-3(dimethylamino)propane ... Urea, n-(3,4-dichlorophenyl)-n'-(4-((3-(dimethylamino)propyl)amino)-6-methyl-2-pyrimidinyl)- …
3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)))
Investigational
Matched Synonyms: … 1,5-naphthyridine, 4-(7-(4-(4-methyl-1-piperazinyl)phenyl)imidazo(1,2-a)pyridin-3-yl)- ... 3-(4-(1,5-napthrydine)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Seralutinib
Investigational
Matched Synonyms: … 3-pyridinecarboxamide, n-(3-((1s)-1-((6-(3,4-dimethoxyphenyl)-2-pyrazinyl)amino)ethyl)phenyl)-5-methyl ... N-(3-((1s)-1-((6-(3,4-dimethoxyphenyl)-2-pyrazinyl)amino)ethyl)phenyl)-5-methyl-3-pyridinecarboxamide …
Tilpisertib
Investigational
Matched Synonyms: … -1-oxo-5-isoquinolinyl)methyl)amino)-8-chloro-4-((2,2-dimethylpropyl)amino)- ... 3-quinolinecarbonitrile, 6-(((s)-(1-bicyclo(1.1.1)pent-1-yl-1h-1,2,3-triazol-4-yl)(1,2-dihydro-2-methyl …
7-methyl-7,8-dihydroguanosine-5'-diphosphate
Experimental
Matched Name: … 7-methyl-7,8-dihydroguanosine-5'-diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
Matched Iupac: … [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
6-(adenosine tetraphosphate-methyl)-7,8-dihydropterin
Experimental
Matched Name: … 6-(adenosine tetraphosphate-methyl)-7,8-dihydropterin …
Alpha-Methyl-N-Acetyl-D-Glucosamine
Experimental
Matched Name: … Alpha-Methyl-N-Acetyl-D-Glucosamine …
threo-3-methyl-L-aspartic acid
Experimental
Matched Synonyms: … (3S)-3-methyl-L-aspartic acid …
Matched Name: … threo-3-methyl-L-aspartic acid …
Matched Name: … threo-3-methyl-L-aspartic acid …
Voacamine
Voacamine is an alkaloid isolated from the bark of the Pescheria fuchsiae folia tree. It is an antimalarial drug approved for use in several African countries. Voacamine is also under investigation for use in modulating multidrug-resistance in tumor cells.
Experimental
Matched Synonyms: … Methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate …
Matched Iupac: … methyl (1S,15S,17S,18S)-17-ethyl-6-[(1R,12R,14R,15E)-15-ethylidene-18-(methoxycarbonyl)-17-methyl-10,17 …
Matched Iupac: … methyl (1S,15S,17S,18S)-17-ethyl-6-[(1R,12R,14R,15E)-15-ethylidene-18-(methoxycarbonyl)-17-methyl-10,17 …
(S)-famoxadone
Experimental
Matched Synonyms: … (S)-5-Methyl-5-(4-phenoxy-phenyl)-3-phenylamino-oxazolidine-2,4-dione …
Matched Iupac: … (5S)-5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione …
Matched Iupac: … (5S)-5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione …
Netarsudil
A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous
As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic solution) 0.02% for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Acting as both a rho...
Approved
Matched Synonyms: … (4-((1S)-1-(Aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4- dimethylbenzoate …
Matched Iupac: … {4-[(1S)-2-amino-1-[(isoquinolin-6-yl)carbamoyl]ethyl]phenyl}methyl 2,4-dimethylbenzoate …
Matched Description: … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel ... conventional trabecular pathway of aqueous humour outflow to act as an inhibitor to the rho kinase and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiglaucoma Preparations and Miotics ... latanoprost and netarsudil …
Matched Iupac: … {4-[(1S)-2-amino-1-[(isoquinolin-6-yl)carbamoyl]ethyl]phenyl}methyl 2,4-dimethylbenzoate …
Matched Description: … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel ... conventional trabecular pathway of aqueous humour outflow to act as an inhibitor to the rho kinase and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiglaucoma Preparations and Miotics ... latanoprost and netarsudil …
Avadomide
Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
Investigational
Matched Synonyms: … 3-(5-Amino-2-methyl-4-oxo-4H-quinazolin-3-yl)piperidine-2,6-dione …
Matched Iupac: … 3-(5-amino-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione …
Matched Description: … , and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma). ... Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292 …
Matched Iupac: … 3-(5-amino-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione …
Matched Description: … , and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma). ... Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292 …
alpha-Ketoisovalerate
Experimental
Matched Synonyms: … 3-Methyl-2-oxobutanoate ... 3-Methyl-2-oxobutyric acid ... 3-Methyl-2-oxobutanoic acid …
Matched Iupac: … 3-methyl-2-oxobutanoic acid …
Matched Iupac: … 3-methyl-2-oxobutanoic acid …
6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER
Experimental
Matched Name: … 6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER …
Matched Iupac: … methyl 6-carbamimidoyl-4-(3-hydroxy-2-methylbenzamido)naphthalene-2-carboxylate …
Matched Iupac: … methyl 6-carbamimidoyl-4-(3-hydroxy-2-methylbenzamido)naphthalene-2-carboxylate …
N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide
Experimental
Matched Name: … N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide …
Matched Iupac: … N-{[(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl]methyl}-N-(2-methylpropyl)benzenesulfonamide …
Matched Iupac: … N-{[(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl]methyl}-N-(2-methylpropyl)benzenesulfonamide …
2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Experimental
Matched Name: … 2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … N-[(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl](tert-butoxy)carboximidic acid …
Matched Iupac: … N-[(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl](tert-butoxy)carboximidic acid …
Displaying drugs 1126 - 1150 of 2186 in total