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Displaying drugs 1126 - 1150 of 1667 in total
Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory And/or Intolerant to Antimalarial Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human blood dendritic cell antigen 2) (human-mus musculus monoclonal biib059 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal biib059 .kappa. …
Matched Description: … And/or Intolerant to Antimalarial Therapy). ... Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And
Investigational
Matched Synonyms: … Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human programmed death-ligand 1) (human ... monoclonal kla167 .gamma.1-chain), disulfide with human monoclonal kla167 .kappa. …
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- ... 2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa. …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … Guanosine 3',5'-cyclic phosphate
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... and it has been found to activate specific protein kinases. ... It is a cellular regulatory agent and has been described as a second messenger. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human IL-7-HYFC ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Approved
Experimental
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids …
Matched Products: … TALCID LIQUID
Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … Recombinant human pentraxin-2 ... RECOMBINANT HUMAN SERUM AMYLOID P ... Serum amyloid P protein (recombinant human PRM 151) …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal ... hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Camoteskimab is under investigation in clinical trial NCT06436183 (A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis).
Investigational
Matched Synonyms: … Immunoglobulin g1 (242-phenylalanine,243-glutamic acid,339-serine), anti-(human interleukin 18) (human ... monoclonal cerc-007 .gamma.1-chain), disulfide with human monoclonal cerc-007 .kappa. …
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions. Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... 152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA. …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct ... Immunoglobulin, anti-(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide ... linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus single-chain …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … It also concentrates in the thyroid gland, salivary glands, gastric mucosa, and choroid plexus. ... following tissues: thyroid, salivary gland, urinary bladder (for detection of vesico-ureteral reflux), and ... technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted and
Matched Mixtures name: … GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Matched Salts name: … Technetium Tc-99m sodium pertechnetate …
Matched Categories: … Indicators and Reagents …
Matched Products: … Sodium Pertechnetate 99mtc Injection …
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion ... protein with human tumor necrosis factor .alpha., trimer …
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
AMT-101 is a recombinant human interleukin-10 fusion protein.
Investigational
Matched Synonyms: … Recombinant human interleukin-10 fusion protein …
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda. ... Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) ... 5) (human-Lama glama clone IF5 single-domain VHH ... fusion protein with peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor …
Matched Description: … Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Alpha-D-Galactose-1-Phosphate
Displaying drugs 1126 - 1150 of 1667 in total