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Displaying drugs 11476 - 11500 of 12677 in total
JB991
JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug...
Investigational
Matched Description: … effect in vivo in an animal model. ... in vitro. ... The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts …
DP-VPA
DP-VPA is D-Pharm's proprietary lipid modified version of valproic acid (VPA) that demonstrate that DP-VPA is well-tolerated in patients with resistant epilepsy and has a marked effect on reducing seizure frequency.
Investigational
Matched Description: … proprietary lipid modified version of valproic acid (VPA) that demonstrate that DP-VPA is well-tolerated in …
BG-777
BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.
Investigational
Matched Description: … BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical …
MEM 1414
MEM 1414 is a PDE4 inhibitor that is being evaluated for the treatment of Alzheimer’s disease. This drug candidate has completed Phase 1 clinical trials. MEM 1414 works by blocking phosphodiesterase, an enzyme that breaks down an important brain chemical, cyclic AMP. It appears to work in the area of...
Investigational
Matched Description: … It appears to work in the area of the brain where new memories are formed. …
TAK-751S
TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic Escherichia coli.
Investigational
Ilodecakin
Investigational
Astaxanthin
Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is found in the majority of aquatic organisms with red pigment. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may...
Investigational
Matched Description: … It is found in the majority of aquatic organisms with red pigment. ... Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. ... It may be found in fish feed or some animal food as a color additive. …
Bivatuzumab
Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. [A31688,A31689]
Investigational
Odiparcil
Investigational
(S)-acetoin
A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
Experimental
Matched Description: … In mammals it is oxidized to carbon dioxide. ... It is a component of the butanediol cycle in microorganisms. …
(R)-acetoin
A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
Experimental
Matched Description: … In mammals it is oxidized to carbon dioxide. ... It is a component of the butanediol cycle in microorganisms. …
Lanraplenib
Lanraplenib is under investigation in clinical trial NCT03285711 (Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)).
Investigational
Matched Description: … Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)). ... Lanraplenib is under investigation in clinical trial NCT03285711 (Safety and Efficacy of Filgotinib and …
BIO-11006
BIO-11006 is under investigation in clinical trial NCT03202394 (Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS).
Investigational
Matched Description: … -11006 Inhalation Solution in Patients With ARDS). ... BIO-11006 is under investigation in clinical trial NCT03202394 (Evaluation of Safety & Efficacy of BIO …
Spartalizumab
Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).
Investigational
Matched Description: … in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma). ... Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 …
Tavolixizumab
Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).
Investigational
Matched Description: … Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult …
Ramatercept
Ramatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women).
Investigational
Matched Description: … and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women). ... Ramatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic …
Fucose
Fucose is under investigation in clinical trial NCT03354533 (Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II).
Investigational
Matched Description: … Fucose is under investigation in clinical trial NCT03354533 (Study of ORL-1F (L-fucose) in Patients With …
MK-0533
MK-0533 is under investigation in clinical trial NCT00543959 (Efficacy and Tolerability of MK0533 in Patients With Type 2 Diabetes (0533-005)).
Investigational
Matched Description: … MK-0533 is under investigation in clinical trial NCT00543959 (Efficacy and Tolerability of MK0533 in …
GSK-3117391
GSK-3117391 is under investigation in clinical trial NCT02965599 (Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK3117391 in Subjects With Rheumatoid Arthritis).
Investigational
Matched Description: … and Pharmacodynamics of GSK3117391 in Subjects With Rheumatoid Arthritis). ... GSK-3117391 is under investigation in clinical trial NCT02965599 (Efficacy, Safety, Tolerability, Pharmacokinetics …
Lorukafusp alfa
Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Investigational
Matched Description: … , and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma). ... Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim …
ISIS 2503
ISIS 2503 is under investigation in clinical trial NCT00004193 (ISIS 2503 in Treating Patients With Metastatic And/or Locally Recurrent Colorectal Cancer).
Investigational
Matched Description: … ISIS 2503 is under investigation in clinical trial NCT00004193 (ISIS 2503 in Treating Patients With Metastatic …
Mesdopetam
Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia).
Investigational
Matched Description: … Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients …
Alintegimod
Alintegimod is under investigation in clinical trial NCT06362369 (A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy).
Investigational
Matched Description: … ) in Combination With Ipilimumab Followed by Nivolumab Monotherapy). ... Alintegimod is under investigation in clinical trial NCT06362369 (A Study of Oral 7HP349 (Alintegimod …
Lepunafusp alfa
Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 Study in Patients With MPS I).
Investigational
Matched Description: … Study in Patients With MPS I). ... Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 …
Eltrekibart
Eltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Description: … in Adult Participants With Moderate to Severe Hidradenitis Suppurativa). ... Eltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) …
Displaying drugs 11476 - 11500 of 12677 in total