Did you mean 375 3,4 2?
Displaying drugs 11501 - 11525 of 12671 in total
Emricasan
Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Investigational
Matched Iupac: … (3S)-3-[(2S)-2-{[(2-tert-butylphenyl)carbamoyl]formamido}propanamido]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy …
Fispemifene
Investigational
Matched Iupac: … 2-(2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethoxy)ethan-1-ol …
BX-528
Experimental
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{hydroxy[(1R)-2-methyl-1-(3-phenylpropanesulfonamido)propyl]phosphoryl …
CAP-1
Experimental
Matched Iupac: … 1-(3-chloro-4-methylphenyl)-3-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}urea …
Tipelukast
Tipelukast is under investigation for the treatment of IPF and Idiopathic pulmonary fibrosis.
Investigational
Matched Iupac: … 4-(6-acetyl-3-{3-[(4-acetyl-3-hydroxy-2-propylphenyl)sulfanyl]propoxy}-2-propylphenoxy)butanoic acid …
Dexelvucitabine
Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
Investigational
Matched Iupac: … 4-amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1,2-dihydropyrimidin-2-one …
Teclozan
Teclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
Experimental
Matched Iupac: … 2,2-dichloro-N-[(4-{[2,2-dichloro-N-(2-ethoxyethyl)acetamido]methyl}phenyl)methyl]-N-(2-ethoxyethyl)acetamide …
Etanautine
Experimental
Matched Iupac: … 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetic acid; [2-(diphenylmethoxy)ethyl]dimethylamine …
Tavapadon
Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects).
Investigational
Matched Iupac: … 1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1,2,3,4-tetrahydropyrimidine …
ORM-13070 C-11
ORM-13070 C-11 is under investigation in clinical trial NCT00735774 (Suitability of 11C-ORM-13070 as a PET Tracer).
Investigational
Matched Iupac: … 1-{[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl}-4-{3-[(11C)methoxymethyl]pyridin-2-yl}piperazine …
OMS-824
Investigational
Matched Iupac: … N'-[(E)-(4-bromo-3,5-dimethoxyphenyl)methylidene]-2-methoxy-2-[4-(1H-pyrazol-1-yl)phenyl]acetohydrazide …
ZYIL-1
Investigational
Matched Iupac: … 3-[(1E)-2-[(2R)-1,2-dimethylpyrrolidin-2-yl]ethenesulfonyl]-1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea …
Darapladib
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-2-(2-{[(4-fluorophenyl)methyl]sulfanyl}-4-oxo-1H,4H,5H,6H,7H-cyclopenta[d]pyrimidin ... -1-yl)-N-{[4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]methyl}acetamide …
Pirarubicin
Investigational
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yloxy]oxan-2-yl]oxy}-6,8,11-trihydroxy-8- ... (2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione …
Prednimustine
Prednimustine has been used in trials studying the treatment of Lymphoma.
Investigational
Matched Iupac: … -3,6-dien-14-yl]-2-oxoethyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoate ... 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca …
XV638
Experimental
Matched Iupac: … 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-2-oxo-3-({3-[(1,3-thiazol-2-yl)carbamoyl]phenyl}methyl)- ... 1,3-diazepan-1-yl]methyl}-N-(1,3-thiazol-2-yl)benzamide …
Nigericin
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Experimental
Matched Iupac: … [4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoic acid ... (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl ... )-3,5-dimethyloxan-2-yl]-2,3'-dimethyl-[2,2'-bioxolan]-5-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro …
Matched Salts cas: … 28643-80-3 …
Matched Salts cas: … 28643-80-3 …
Ifebemtinib
Investigational
Matched Iupac: … 2-fluoro-5-methoxy-4-({4-[(2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)pyrimidin ... -2-yl}amino)-N-(1-methylpiperidin-4-yl)benzamide …
Bis(5-Amidino-Benzimidazolyl)Methane
Experimental
Matched Iupac: … {[2-({6-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}methyl)-1H-1,3-benzodiazol-6-yl](azaniumyl)methylidene …
OSI-7836
OSI-7836 is a member of the nucleoside class of cytotoxic drugs of which gemcitabine is the market leader. OSI Pharmaceuticals develops OSI-7836 as a next-generation gemcitabine. The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. It is also more active than ara-C (another clinically used nucleoside...
Investigational
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidine-2-thione …
BMS-564929
BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.
Experimental
Matched Iupac: … 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile …
Capravirine
Investigational
Matched Iupac: … {5-[(3,5-dichlorophenyl)sulfanyl]-4-(propan-2-yl)-1-[(pyridin-4-yl)methyl]-1H-imidazol-2-yl}methyl carbamate …
Berzosertib
Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
Investigational
Matched Iupac: … 3-(3-{4-[(methylamino)methyl]phenyl}-1,2-oxazol-5-yl)-5-[4-(propane-2-sulfonyl)phenyl]pyrazin-2-amine …
Omigapil
Omigapil has been used in trials studying the treatment of Congenital Muscular Dystrophy.
Investigational
Matched Iupac: … methyl({2-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-9-yl}methyl)(prop-2-yn-1-yl …
CH-5132799
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … 5-[7-methanesulfonyl-2-(morpholin-4-yl)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrimidin-2-amine …
Matched Categories: … Class I Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Categories: … Class I Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Displaying drugs 11501 - 11525 of 12671 in total