Displaying drugs 11526 - 11550 of 11814 in total
Agerafenib
Agerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
Investigational
Matched Iupac: … 1-{3-[(6,7-dimethoxyquinazolin-4-yl)oxy]phenyl}-3-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol …
Etheno-NAD
Experimental
Matched Iupac: … 3-carbamoyl-1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-{3H-imidazo[2,1-f]purin-3-yl}oxolan ... 2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-1lambda5-pyridin-1- …
Nadide
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono ... hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1- …
Matched Description: … A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate …
Matched Description: … A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate …
MK-2748
MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).
Investigational
Matched Iupac: … (1R,18R,22R,26S,29S)-26-cyclopentyl-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl} …
Taniraleucel
Investigational
Salophen iron chelate
Experimental
Matched Iupac: … lambda4-iron(4+) 2-[(E)-({2-[(E)-[(2-oxidophenyl)methylidene]amino]phenyl}imino)methyl]benzen-1-olate …
Glibornuride
Glibornuride is a sulfonylurea-type anti-diabetic drug.
Investigational
Withdrawn
Matched Iupac: … 3-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Maropitant
Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
Vet approved
Matched Iupac: … (2S,3S)-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-2-(diphenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine …
Matched Salts cas: … 359875-09-5 …
Matched Salts cas: … 359875-09-5 …
Tofimilast
Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … 12-cyclopentyl-10-ethyl-5-(thiophen-2-yl)-3,4,6,11,12-pentaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,10 …
Delanzomib
Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin.
Investigational
Matched Iupac: … [(1R)-1-[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)formamido]butanamido]-3-methylbutyl]boronic acid …
Taprenepag
Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Iupac: … 2-{3-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]phenoxy}acetic acid …
Raluridine
Raluridine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … 5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Tenidap
Experimental
Matched Iupac: … (3Z)-5-chloro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indole-1-carboxamide …
Acalisib
Acalisib is under investigation in clinical trial NCT01705847 (A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies).
Investigational
Matched Iupac: … 6-fluoro-3-phenyl-2-[(1S)-1-[(7H-purin-6-yl)amino]ethyl]-3,4-dihydroquinazolin-4-one …
Fluazuron
Fluazuron is a benzoyl phenylurea compound.
Experimental
Matched Iupac: … 3-(4-chloro-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1-(2,6-difluorobenzoyl)urea …
PT-2385
PT-2385 is under investigation in clinical trial NCT03108066 (PT2385 for the Treatment of Von Hippel-lindau Disease-associated Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … 3-{[(1S)-2,2-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile …
AMG-319
Investigational
Matched Iupac: … N-[(1S)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl]-9H-purin-6-amine …
A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor
Experimental
Matched Iupac: … (2S,3R)-N-hydroxy-2-(3-hydroxypropyl)-N'-[(3S)-1-(2-methoxyethyl)-2-oxoazepan-3-yl]-3-(2-methylpropyl …
6-Deoxyerythronolide B
Experimental
Matched Iupac: … (3R,4S,5R,6S,7S,9R,11R,12S,13R,14R)-14-ethyl-4,6,12-trihydroxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane …
Adomeglivant
Adomeglivant has been investigated for the basic science of Type 2 Diabetes.
Investigational
Matched Iupac: … 3-({4-[(1S)-1-({4'-tert-butyl-2,6-dimethyl-[1,1'-biphenyl]-4-yl}oxy)-4,4,4-trifluorobutyl]phenyl}formamido …
BMS-394136
BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.
Investigational
Matched Iupac: … (2S)-1-[(7R)-7-(3,4-dichlorophenyl)-5-methyl-4H,7H-pyrazolo[1,5-a]pyrimidine-6-carbonyl]-2-(4-fluorophenyl …
Nicotinamide adenine dinucleotide cyclohexanone
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy ... -pyridin-1-ylium ... )phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-4-[(1S)-2-oxocyclohexyl]-1lambda5 …
Violaxanthin
Experimental
Matched Iupac: … 4.1.0]heptan-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-1,5,5-trimethyl-7 ... (1R,3S,6S)-6-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[ …
25-desacetylrifapentine
25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine).
Investigational
Matched Iupac: … (7S,9E,11S,12S,13S,14R,15R,16R,17S,18S,19E,21E)-26-[(E)-[(4-cyclopentylpiperazin-1-yl)imino]methyl]-2,13,15,17,27,29 ... methoxy-3,7,12,14,16,18,22-heptamethyl-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1( …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Anatibant
Anatibant is a selective, very potent, small-molecule Bradykinin B2 receptor antagonist. It is developed for the for the treatment of traumatic brain injury (TBI).
Investigational
Matched Iupac: … 4-carbamimidoyl-N-(3-{[(2S)-1-(2,4-dichloro-3-{[(2,4-dimethylquinolin-8-yl)oxy]methyl}benzenesulfonyl …
Displaying drugs 11526 - 11550 of 11814 in total