AMG-319

DB16879InvestigationalSmall molecule

AMG-319: Overview.

Mechanism: Pharmacologically active on Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Curator reviewed
Formula / weight: C₂₁H₁₆FN₇ · 385.406 g/mol (avg)
Code names: AMG-319

Resolves to

Compound

Structure

InChIKeyKWRYMZHCQIOOEB-LBPRGKRZSA-NSMILESC[C@H](NC1=C2N=CNC2=NC=N1)C1=CC2=C(C=C(F)C=C2)N=C1C1=NC=CC=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with AMG-319, and which of those have an active Phase 3 trial?

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