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Displaying drugs 11551 - 11575 of 12856 in total
SQ-109
SQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen.
Investigational
Matched Iupac: … N-(2-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]amino}ethyl)adamantan-2-amine …
(S)-carazolol
Experimental
Matched Iupac: … (2S)-1-(9H-carbazol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
(1S)-menthyl hexyl phosphonate group
Experimental
Matched Iupac: … hexyl({[(1S,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy})phosphinic acid …
PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID
Experimental
Matched Iupac: … (3R)-3-hydroxy-3-({2-[(2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropyl 2,2-dimethylpropanoate …
Clinofibrate
Clinofibrate is a fibrate drug sold and marketed in Japan.
Experimental
Matched Iupac: … 2-(4-{1-[4-(1-carboxy-1-methylpropoxy)phenyl]cyclohexyl}phenoxy)-2-methylbutanoic acid …
Enobosarm
Enobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer.
Investigational
Matched Iupac: … (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide …
Pimonidazole
Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.
Investigational
Matched Iupac: … 1-(2-nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol …
Ataciguat
Ataciguat has been investigated for the basic science of Aortic Valve Stenosis.
Investigational
Matched Iupac: … 5-chloro-2-(5-chlorothiophene-2-sulfonamido)-N-[4-(morpholine-4-sulfonyl)phenyl]benzamide …
Miridesap
Miridesap has been used in trials studying the prevention of HIV and treatment of AL amyloidosis.
Investigational
Matched Iupac: … (2R)-1-{6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl}pyrrolidine-2-carboxylic acid …
Azidamfenicol
Experimental
Matched Iupac: … 2-azido-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide …
Cinepazet
Experimental
Matched Iupac: … ethyl 2-{4-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]piperazin-1-yl}acetate …
Ligandrol
Ligandrol is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis.
Investigational
Matched Iupac: … 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile …
Enrasentan
Investigational
Matched Iupac: … (1S,2R,3S)-1-(2H-1,3-benzodioxol-5-yl)-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-5-propoxy-2,3-dihydro- ... 1H-indene-2-carboxylic acid …
Dorzagliatin
Dorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Investigational
Matched Iupac: … (2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-N-{1-[(2R)-2,3-dihydroxypropyl]-1H-pyrazol …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Iupac: … (2S)-2-{2-[(4S,5S)-20-carboxy-4-(2-carboxyethyl)-10-ethenyl-15-ethyl-5,9,14,19-tetramethyl-21,22,23,24 ... tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),6,8,10,12,14,16(22),17,19-decaen-2- …
Brifentanil
Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable...
Illicit
Matched Iupac: … N-[(3R,4S)-1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-3-methylpiperidin-4-yl]-N- ... (2-fluorophenyl)-2-methoxyacetamide …
Gisadenafil
Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
Investigational
Matched Iupac: … 5-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]pyridin-3-yl}-3-ethyl-2-(2-methoxyethyl)-2H,6H,7H-pyrazolo …
Matched Categories: … Cyclic Nucleotide Phosphodiesterases, Type 5 …
Matched Categories: … Cyclic Nucleotide Phosphodiesterases, Type 5 …
Lazertinib
Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Iupac: … N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin ... -4-yl)phenyl}prop-2-enamide …
Ningetinib
Ningetinib is under investigation in clinical trial NCT03758287 (Ningetinib (CT053PTSA) Plus Gefitinib in Stage IIIB or IV NSCLC Patients With EGFR Mutation and T790M Negative).
Investigational
Matched Iupac: … N-(3-fluoro-4-{[7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl]oxy}phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3 …
Amphomycin
Vet approved
Matched Iupac: … (2S)-3-carboxy-2-[(3E)-10-methyldodec-3-enamido]propanamido]-2-methylpropanoic acid ... [1,2-a]pyrazin-3-yl]ethyl]carbamoyl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamoyl}-2-aminopropyl ... ]carbamoyl}methyl)carbamoyl]-2-carboxyethyl]carbamoyl}methyl)carbamoyl]-2-carboxyethyl]carbamoyl}-3-[ ... (2R,3S)-3-{[(1S)-1-[({[(1S)-1-[({[(1R,2S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-[(3S,9aR)-1,4-dioxo-octahydro-1H-pyrido …
Glutathionylspermidine disulfide
Experimental
Matched Iupac: … (2R)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4R)-4-amino-4-carboxybutanamido]-2-{[({3-[(4-aminobutyl)amino]propyl …
Fentonium
Fentonium is an atropine derivative.
Withdrawn
Matched Iupac: … (1R,3R,5S)-8-(2-{[1,1'-biphenyl]-4-yl}-2-oxoethyl)-3-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-8-methyl …
Preladenant
Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement Disorders, Antipsychotic Agents, and Parkinsonian Disorders, among others.
Investigational
Matched Iupac: … 4-(furan-2-yl)-10-(2-{4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl}ethyl)-3,5,6,8,10,11-hexaazatricyclo …
BMS-986141
BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Investigational
Matched Iupac: … 4-(4-{[(6-methoxy-2-{2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl}-1-benzofuran-4-yl)oxy]methyl}-1,3 ... -thiazol-2-yl)-N,N-dimethylbenzamide …
Fosravuconazole
Fosravuconazole is under investigation in clinical trial NCT03378661 (BENDITA BEnznidazole New Doses Improved Treatment and Associations).
Investigational
Matched Iupac: … ({[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan ... -2-yl]oxy}methoxy)phosphonic acid …
Displaying drugs 11551 - 11575 of 12856 in total