This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Azidamfenicol
DrugBank Accession Number
DB13294
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 295.255
Monoisotopic: 295.091668539
Chemical Formula
C11H13N5O5
Synonyms
  • Azidamfenicol
  • Azidamfenicolum
  • Azidanfenicol
External IDs
  • Bay F 4797
  • Bayer 52910

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcenocoumarolThe risk or severity of bleeding can be increased when Azidamfenicol is combined with Acenocoumarol.
BCG vaccineThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Azidamfenicol.
DicoumarolThe risk or severity of bleeding can be increased when Azidamfenicol is combined with Dicoumarol.
EstetrolThe therapeutic efficacy of Estetrol can be decreased when used in combination with Azidamfenicol.
FluindioneThe risk or severity of bleeding can be increased when Azidamfenicol is combined with Fluindione.
LactuloseThe therapeutic efficacy of Lactulose can be decreased when used in combination with Azidamfenicol.
PhenindioneThe risk or severity of bleeding can be increased when Azidamfenicol is combined with Phenindione.
PhenprocoumonThe risk or severity of bleeding can be increased when Azidamfenicol is combined with Phenprocoumon.
Picosulfuric acidThe therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Azidamfenicol.
Typhoid vaccineThe therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Azidamfenicol.
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Food Interactions
Not Available

Products

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International/Other Brands
Berlicetin / Thilocof

Categories

ATC Codes
S01AA25 — Azidamfenicol
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Amino acids, peptides, and analogues
Direct Parent
Alpha amino acids and derivatives
Alternative Parents
Nitrobenzenes / Nitroaromatic compounds / Secondary carboxylic acid amides / Secondary alcohols / Azo imides / Azo compounds / Propargyl-type 1,3-dipolar organic compounds / Organic oxoazanium compounds / Primary alcohols / Organopnictogen compounds
show 5 more
Substituents
Alcohol / Allyl-type 1,3-dipolar organic compound / Alpha-amino acid or derivatives / Aromatic alcohol / Aromatic homomonocyclic compound / Azo compound / Azo imide / Benzenoid / C-nitro compound / Carbonyl group
show 19 more
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
40257685LM
CAS number
13838-08-9
InChI Key
SGRUZFCHLOFYHZ-MWLCHTKSSA-N
InChI
InChI=1S/C11H13N5O5/c12-15-13-5-10(18)14-9(6-17)11(19)7-1-3-8(4-2-7)16(20)21/h1-4,9,11,17,19H,5-6H2,(H,14,18)/t9-,11-/m1/s1
IUPAC Name
2-azido-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMILES
OC[C@@H](NC(=O)CN=[N+]=[N-])[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O

References

General References
Not Available
ChemSpider
56590
ChEBI
135238
ChEMBL
CHEMBL3989525
ZINC
ZINC000043649866
Wikipedia
Azidamfenicol

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility1.22 mg/mLALOGPS
logP0.74ALOGPS
logP-0.4ChemAxon
logS-2.4ALOGPS
pKa (Strongest Acidic)11.94ChemAxon
pKa (Strongest Basic)-2.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area142.13 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity70.22 m3·mol-1ChemAxon
Polarizability26.91 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 23, 2017 20:39 / Updated at February 21, 2021 18:54