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Displaying drugs 1151 - 1175 of 1543 in total

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Alimentary Tract and Metabolism ... Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … คอเลแมกซ์ 100 ... URSOCOLIK 250MG KAPSÜL,100 ADET ... URSOMED 300 MG KAPSÜL 100 KAPSÜL …

Palopegteriparatide

Palopegteriparatide is a mPEG conjugated parathyroid hormone 1-34.
Investigational
Matched Synonyms: … , conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x …
Matched Categories: … Parathyroid Hormones and Analogues ... Sex Hormones and Insulins ... Thyroid Products …

Avutometinib

Avutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and RO5126766.).
Investigational
Matched Synonyms: … Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl …
Matched Description: … RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and …

Enalapril

Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Products: … ENALAPRIL TABLETAS X 5MG ... ENALAPRIL TABLETAS X 20 MG …

Iron sucrose

Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Avofer Injection 100mg/5ml ... Ranofer Injection 100mg/5ml ... VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET …

Zidovudine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Description: … It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … Abacavir Sulfate, Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... Nucleic Acids, Nucleotides, and Nucleosides ... zidovudine, lamivudine and nevirapine ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … RETROVIR 100 MG KAPSÜL, 100 ADET ... ZIDOMAT 100 (Zidovudine Tablets USP 100mg) ... ZIDOVEX - 100 (Zidovudine capsules USP 100mg) …

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and ... and proteolysis among many other functions. ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … APIDRA(100 UNITS/ML) ... APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL …

2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate

Experimental
Matched Name: … 2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … tert-butyl N-[(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Salts name: … Chloroquine sulfate …
Matched Categories: … chloroquine and proguanil ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 1000 ADET …

Trisaccharide B

Investigational
Matched Synonyms: … -l-fuc-(1->2))-d-gal …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … XPREZA 100 INJECTION 100 MG/VIAL ... ARGAXIT®100 MG ... NEXTIDINA® 100 MG …

Danazol

A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Description: … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary ... Danazol has been used in the treatment of endometriosis and some benign breast disorders. …
Matched Categories: … Antigonadotropins and Similar Agents ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … DANASIN 100 MG KAPSUL, 100 ADET ... วาบอน-100 ... อนาจิล (100 มก.) …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … TEROPROS FILM COATED TABLET 1000MG ... Abirateron Sandoz 1000 mg – Filmtabletten ... Abirateron 1A Pharma 1000 mg – Filmtabletten …

Etoposide toniribate

Investigational
Matched Synonyms: … 6-oxo-5,5a,6,8,8a,9-hexahydro-2h-furo(3',4':6,7)naphtho(2,3-d)(1,3)dioxol-5-yl)-2,6-dimethoxyphenyl carbonate …
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZALIPIN 100 MG KAPSÜL ,100 KAPSÜL ... EPİZONYA 100 MG KAPSÜL, 100 ADET ... EXCEGRAN 100 MG KAPSUL, 100 ADET …

Norethisterone

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone Acetate and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol, and Ferrous Fumarate …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... norethisterone and estrogen ... Genito Urinary System and Sex Hormones …
Matched Products: … PRIMOLUT-N 5 MG TABLET, 1000 ADET …

Pimozide

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994,...
Approved
Matched Description: … A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol ... for the suppression of vocal and motor tics in patients with Tourette syndrome. …
Matched Products: … NOROFREN 2 MG TABLET, 1000 ADET …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … Qudexy XR ... Trokendi XR ... EXPLIGA XR …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics …
Matched Products: … Demerol 100 mg/ml ... DEMOTHINE INJECTION 100MG/2ML ... Demerol 10%-liq Im Sc 100mg/ml …

Posaconazole

Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Description: … Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOXAFIL TABLET 100MG ... Ossmiq 100 mg - magensaftresistente Tabletten ... Noxafil 100mg Modified Release Tablet …

Iron polymaltose

Experimental
Matched Mixtures name: … HERREX® FOL 1000 TABLETAS RECUBIERTAS ... FERLOS 100 MG/0.35 MG TABLET, 30 ADET ... SANTAFER FORT 100MG/0,35 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … DUNOXSOL 100 ... MALTOFER FILM-COATED TABLETS 100MG ... SANTAFER 100MG/2ML AMPUL, 5 ADET …

Aceclofenac

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AINEDIX AC® 100 MG ... AIRTAL FILM COATED TABLETS 100mg ... Airtal 100mg Film-coated Tablet …

Racecadotril

Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
Investigational
Matched Description: … Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … easystop 100 mg Hartkapseln ... Hidrasec 100 mg Hartkapseln ... HIDRASEC CAPSULAS 100 MG …

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable ... Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. …
Matched Mixtures name: … BROMUX D® 100/300 MG CÁPSULA. …
Matched Salts name: … Pinaverium bromide …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Matched Products: … PYNAZER® 100 MG ... BROMUX 100MG TABLETAS. ... DICETEL® TABLETAS 100 MG …

Sapropterin

Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Description: … phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Matched Products: … KUVAN® 100 MG ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 120 ADET ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 240 ADET …
Displaying drugs 1151 - 1175 of 1543 in total