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Displaying drugs 11826 - 11850 of 12332 in total
Experimental
Matched Iupac: … (2S)-2-amino-3-[1-(2H-1,2,3,4-tetrazol-5-yl)-1H-imidazol-4-yl]propanal …
Experimental
Matched Iupac: … (E)-[(4S)-4-amino-4-carboxybutyl]({amino[(prop-2-en-1-yl)amino]methylidene})azanium …
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(hydroxymethyl)sulfanyl]ethyl]carbamoyl}butanoic …
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(S)-sulfino]ethyl]carbamoyl}butanoic acid …
Experimental
Matched Iupac: … 2-{[(R)-{[4-(aminomethyl)phenyl]amino}({[(1R)-1-phenylethyl]amino})methyl]amino}ethane-1,1-diol …
Investigational
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(dimethylarsanyl)sulfanyl]ethyl]carbamoyl}butanoic …
3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid is a solid. This compound belongs to the aminobenzoic acid derivatives. These are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase.
Experimental
Matched Iupac: … 3-[2-(3,5-diimino-4,5-dihydro-3H-pyrazol-4-ylidene)hydrazin-1-yl]benzoic acid …
ZSTK474 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Iupac: … 1-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-2-(difluoromethyl)-1H-1,3-benzodiazole …
Experimental
Matched Iupac: … 1-[2-(dimethylamino)ethyl] 4-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyl butanedioate …
Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Experimental
Matched Iupac: … (2S,4S)-4-cyclohexyl-1-{2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylic acid …
Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
Investigational
Matched Iupac: … (2E)-3-[4-({[(adamantan-1-yl)methyl](methyl)amino}methyl)phenyl]-N-hydroxyprop-2-enamide …
PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Investigational
Matched Iupac: … 1-[(5S)-5-hydroxy(4,4,6,6,6-2H5)hexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients). ... PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Investigational
Matched Iupac: … [({4-[(1E)-2-{4-[benzyl(ethyl)amino]phenyl}diazen-1-yl]phenyl}carbamoyl)methyl]triethylazanium …
Asoprisnil (J867) is a selective progesterone receptor modulator. It can be used to treat progesterone sensitive myomata.
Investigational
Matched Iupac: … (1S,3aS,3bS,10R,11aS)-10-{4-[(E)-(hydroxyimino)methyl]phenyl}-1-methoxy-1-(methoxymethyl)-11a-methyl- …
Experimental
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,11aS)-5-chloro-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH, …
Experimental
Matched Iupac: … methyl 3-[(1R)-9,14-diethenyl-20-(3-methoxy-3-oxopropyl)-5,10,15,19-tetramethyl-2,22,23,25-tetraaza-1- ... ferraoctacyclo[11.9.1.1^{1,8}.1^{3,21}.0^{2,6}.0^{16,23}.0^{18,22}.0^{11,25}]pentacosa-3(24),4,6,8,10,12,14,16,18,20 …
Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Investigational
Matched Iupac: … oxo-1,2-dihydropyrimidin-1-yl)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-amino-5-(6-amino-9H-purin-9-yl)oxolan ... -1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(2-amino-6-oxo-6,9 ... )amino]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl 3-hexadecanamido-2- ... -1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(5-methyl-2,4-dioxo ... )amino]oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(6-amino-9H-purin-9-yl)oxolan-2-yl]methoxy}( …
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Iupac: … yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione ... (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4- …
Experimental
Matched Iupac: … (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6}.1^{8,12 ... }.1^{14,18}.0^{27,31}.0^{22,33}]hexatriaconta-3,5,8(34),9,11,18(33),19,21,24(32),25,27(31),35-dodecaene …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations).
Investigational
Matched Iupac: … [(2E)-3-({4-[(3-bromo-4-chlorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}carbamoyl)prop-2-en-1-yl]dimethyl ... [(1-methyl-4-nitro-1H-imidazol-5-yl)methyl]azanium …
Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-4-(trifluoromethoxy)benzen-1-olate …
HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.
Investigational
Matched Iupac: … 2-(4-fluorophenyl)-6-methanesulfonamido-N-methyl-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide …
Experimental
Matched Iupac: … 3-[3-(carbamimidamidooxy)propoxy]-5-chloro-N-cyclopentyl-N-(prop-2-en-1-yl)benzamide …
Experimental
Matched Iupac: … (2S)-2-({[(1R)-1-carboxy-2-{[(4-fluorophenyl)methyl]sulfanyl}ethyl]carbamoyl}amino)pentanedioic acid …
9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others.
Investigational
Matched Iupac: … (2E,4E,6Z)-3,7-dimethyl-8-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidene]octa-2,4,6-trienoic acid …
Displaying drugs 11826 - 11850 of 12332 in total