Displaying drugs 11876 - 11900 of 12714 in total
Diphenyleneiodonium
An NADPH oxidase 2 (NOX2) inhibitor.
Investigational
Matched Description: … An NADPH oxidase 2 (NOX2) inhibitor.[A252987] …
Cytidine-5'-Triphosphate
Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem] …
Matched Description: … A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem] …
S-propylamine-L-cysteine
Experimental
Matched Iupac: … (2R)-2-amino-3-[(3-aminopropyl)sulfanyl]propan-1-ol …
Cocamidopropyl betaine
Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and a polar group at...
Experimental
Matched Description: … a polar group at each end. ... It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and ... Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
humanized SMART Anti-IL-12 Antibody
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Description: … IL-12 is a cytokine that may have considerable potential as a target in the therapy of autoimmune diseases ... SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together …
Pteroic acid
Experimental
Matched Iupac: … 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
ATL1101
ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis. ATL1101 is being developed as a cream for the topical treatment of mild to moderate cases of psoriasis.
Investigational
Matched Description: … a protein involved in the regulation of cell overgrowth in psoriasis. ... ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, ... ATL1101 is being developed as a cream for the topical treatment of mild to moderate cases of psoriasis …
ADL5859
ADL5859 is a novel, oral compound that targets the Delta opioid receptor. Delta receptor agonists are thought to offer benefits over other approaches to the management of pain.
Investigational
Matched Description: … ADL5859 is a novel, oral compound that targets the Delta opioid receptor. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
NVS antibody
This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune diseases.
Investigational
Anacetrapib
Investigational
Matched Iupac: … (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl ... )-[1,1'-biphenyl]-2-yl]methyl}-4-methyl-1,3-oxazolidin-2-one …
Arverapamil
Investigational
Matched Iupac: … (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile …
Apabetalone
Apabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease.
Investigational
Matched Iupac: … 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-1,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Salvinorin A
Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
Investigational
Matched Name: … Salvinorin A …
Matched Iupac: … methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro ... -1H-naphtho[2,1-c]pyran-7-carboxylate …
Matched Description: … Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. …
Matched Iupac: … methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro ... -1H-naphtho[2,1-c]pyran-7-carboxylate …
Matched Description: … Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. …
Abexinostat
Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
Investigational
Matched Iupac: … 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide …
Matched Description: … It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Aleplasinin
Aleplasinin has been investigated in Alzheimer Disease.
Investigational
Matched Iupac: … 2-{1-[(4-tert-butylphenyl)methyl]-5-(3-methylphenyl)-1H-indol-3-yl}-2-oxoacetic acid …
Acoziborole
SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.
Investigational
Matched Iupac: … 4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydro-2,1-benzoxaborol-6-yl)-2-(trifluoromethyl)benzamide …
Artemisinin
Artemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
Investigational
Azanidazole
Experimental
Matched Iupac: … 4-[(E)-2-(1-methyl-5-nitro-1H-imidazol-2-yl)ethenyl]pyrimidin-2-amine …
Acetoxolone
Experimental
Matched Iupac: … 6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2- …
Aurotioprol
Experimental
Matched Iupac: … gold(1+) ion sodium 2-hydroxy-3-sulfanidylpropane-1-sulfonate …
Silicic acid
Experimental
Adafosbuvir
Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
Investigational
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2S,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-fluoro-3,4- ... dihydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal …
Matched Description: … Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal …
Apararenone
Apararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).
Investigational
Matched Iupac: … N-[4-(4-fluorophenyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl]methanesulfonamide …
Displaying drugs 11876 - 11900 of 12714 in total