Displaying drugs 12026 - 12050 of 12647 in total
Cofirasersen
Cofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)).
Investigational
Matched Description: … investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of …
AVI-4065
AVI-4065, a phosphorodiamidate Morpholino oligomer (PMO), is an investigational antisense HCV drug. It was developed by Sarepta Therapeutics, Inc. After phase II trials it was cancelled due to lack of potency.
Investigational
Matched Description: … After phase II trials it was cancelled due to lack of potency. [L2917] …
Q-Derp1
Q-Derp1 is developed by Cytos Biotechnology as an immunodrug. It is an antigen for the prevention of various major chronic diseases. Derp1 is the dominant allergic protein found in dust mite feces.
Investigational
Matched Description: … It is an antigen for the prevention of various major chronic diseases. …
NXN-188
NXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.
Investigational
Matched Description: … nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of …
Talsupram
Talsupram is a selective norepinephrine reuptake inhibitor (NRI). It was under research for the treatment of depression in 1960 and 1970 but it was never marketed. Talsupram presents a similar structure to citalopram.
Experimental
Matched Description: … It was under research for the treatment of depression in 1960 and 1970 but it was never marketed. …
USL-311
USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)).
Investigational
Matched Description: … USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in …
Ligufalimab
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Description: … It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With …
TAK-754
TAK-754 is an adeno-associated virus serotype 8 vector (AAV8) expressing B domain deleted codon optimized factor VIII. Developed by Takeda, it is being investigated for the treatment of hemophilia A.
Investigational
Matched Description: … Developed by Takeda, it is being investigated for the treatment of hemophilia A.[A259831] …
Ubamatamab
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Matched Description: … Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone …
Retatrutide
Retatrutide is under investigation in clinical trial NCT06354660 (Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)).
Investigational
Matched Description: … Retatrutide is under investigation in clinical trial NCT06354660 (Effect of Retatrutide Compared With …
rPSGL-Ig
Recombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.
Investigational
Matched Description: … Recombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human …
MLN576
XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.
Investigational
Matched Description: … XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both …
Anpocogin
Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity.
Investigational
Matched Description: … Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/ …
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
Investigational
Matched Description: … 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of …
JNJ-40411813
JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.
Investigational
Matched Description: … JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia …
PF-03715455
PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Description: … PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive …
Ebselen
Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Investigational
Matched Description: … Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes …
Zelavespib
Zelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Investigational
Matched Description: … Zelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic …
Ilginatinib
NS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.
Investigational
Matched Description: … NS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera …
ABX-464
ABX-464 is under investigation in clinical trial NCT03905109 (Safety Evaluation of ABX464 in Patients With Moderate to Severe Active Crohn's Disease).
Investigational
Matched Description: … ABX-464 is under investigation in clinical trial NCT03905109 (Safety Evaluation of ABX464 in Patients …
Bermekimab
Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Investigational
Matched Description: … Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of …
Firtecan pegol
Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
Investigational
Matched Description: … Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients …
Edasalonexent
Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes).
Investigational
Matched Description: … Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of …
Beinaglutide
Beinaglutide is under investigation in clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus).
Investigational
Matched Description: … clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of …
Vunakizumab
Vunakizumab is under investigation in clinical trial NCT03463187 (Multi-Dose Study of SHR-1314 in Subjects With Moderate-to-severe Plaque Psoriasis).
Investigational
Matched Description: … Vunakizumab is under investigation in clinical trial NCT03463187 (Multi-Dose Study of SHR-1314 in Subjects …
Displaying drugs 12026 - 12050 of 12647 in total