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Displaying drugs 12026 - 12050 of 12824 in total
Arachidonic Acid
An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes,...
Experimental
Matched Description: … It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent ... It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins …
RO7284755
RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein. RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or Metastatic Solid Tumors).
Investigational
Matched Description: … Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or ... RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor …
MK-8666
MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).
Investigational
Matched Description: … and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)). ... MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, …
Agatolimod
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Matched Description: … Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients …
Tigatuzumab
Tigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Tigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel ... in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)). …
Nimacimab
Nimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)).
Investigational
Matched Description: … After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)). ... Nimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 …
Rasdegafusp alfa
Rasdegafusp alfa is under investigation in clinical trial NCT03206047 (Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer).
Investigational
Matched Description: … Rasdegafusp alfa is under investigation in clinical trial NCT03206047 (Atezolizumab, Guadecitabine, and ... CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal …
Methylsamidorphan
Methylsamidorphan is under investigation in clinical trial NCT01418092 (ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)).
Investigational
Matched Description: … and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)). ... Methylsamidorphan is under investigation in clinical trial NCT01418092 (ALK37-007: Evaluation of Safety …
Iscalimab
Iscalimab is under investigation in clinical trial NCT03905525 (Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome).
Investigational
Matched Description: … Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome). ... Iscalimab is under investigation in clinical trial NCT03905525 (Study of Safety and Efficacy of Multiple …
Hypothiocyanite ion
Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients).
Investigational
Matched Description: … -009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients). ... Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX …
Revusiran
Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)).
Investigational
Matched Description: … Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study ... of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy …
Xentuzumab
Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib ... in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)). …
GTI-2040
GTI-2040 is under investigation in clinical trial NCT00084643 (GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors).
Investigational
Matched Description: … GTI-2040 is under investigation in clinical trial NCT00084643 (GTI-2040, Oxaliplatin, and Capecitabine ... in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors). …
Marzeptacog alfa (activated)
Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia).
Investigational
Matched Description: … And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia ... Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics …
Elgemtumab
Elgemtumab is under investigation in clinical trial NCT02167854 (Open-Label Study Evaluating the Safety and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer).
Investigational
Matched Description: … Elgemtumab is under investigation in clinical trial NCT02167854 (Open-Label Study Evaluating the Safety ... and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer). …
Adagloxad simolenin
Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC).
Investigational
Matched Description: … (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC). ... Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin …
Dapansutrile
Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Investigational
Matched Description: … Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee). ... Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 …
Ladostigil
Ladostigil is under investigation in clinical trial NCT01429623 (A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment).
Investigational
Matched Description: … and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment). ... Ladostigil is under investigation in clinical trial NCT01429623 (A 3 Year Study to Evaluate the Safety …
Sepofarsen
Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)).
Investigational
Matched Description: … , Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)). ... Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety …
Nadecnemab
Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee).
Investigational
Matched Description: … Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee). ... Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and …
Bosakitug
Bosakitug (BSI-045B) is under investigation in clinical trial NCT05932654 (POC Study to Evaluate BSI-045B Monotherapy and BSI-045B Add-on Therapy With Dupilumab in Atopic Dermatitis).
Investigational
Matched Description: … 045B Monotherapy and BSI-045B Add-on Therapy With Dupilumab in Atopic Dermatitis). ... Bosakitug (BSI-045B) is under investigation in clinical trial NCT05932654 (POC Study to Evaluate BSI- …
LX1031
LX1031 is an orally-dosed drug candidate for irritable bowel syndrome and other gastrointestinal disorders. LX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key control point for the regulation of peripheral serotonin levels. LX1031 is designed to act locally in the gastrointestinal tract by...
Investigational
Matched Description: … LX1031 is designed to act locally in the gastrointestinal tract by reducing the serotonin available for ... receptor activation, without affecting serotonin levels in the brain or its central nervous system functions …
AVR118
AVR118 represents a new type of biopolymer chemistry that also possesses novel immunomodulator activity. This non-toxic peptide-nucleic acid, which to date has shown no indication of human toxicity, appears to stimulate the proinflammatory responses required to combat viral infections such as AIDS and human papilloma virus and to dampen aberrant...
Investigational
Matched Description: … AVR118 is being studied for the promise shown in its ability to mitigate the toxic side effects of other ... that have been damaged by chemotherapeutic agents) and for its ability to treat cachexia (wasting) in ... drugs (including those used to treat HIV infection and chemotherapeutic drugs employed in the treatment …
Fasinumab
Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). It is currently under investigation for the treatment osteoarthritic pain and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy (i.e. NSAIDs and/or opioids) in this patient population. NGF was first discovered...
Investigational
Matched Description: … NSAIDs and/or opioids) in this patient population. ... become an attractive target in the treatment of chronic pain conditions. ... [A241165]
NGF was first discovered in the 1950s[A241180] and was the first neurotrophic factor to …
Duligotuzumab
Duligotuzumab has been used in trials studying the treatment of Neoplasms, Colorectal Cancer, Head and Neck Cancer, and Epithelial Tumors, Malignant.
Investigational
Matched Description: … Duligotuzumab has been used in trials studying the treatment of Neoplasms, Colorectal Cancer, Head and …
Displaying drugs 12026 - 12050 of 12824 in total