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Displaying drugs 1201 - 1225 of 1372 in total
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … Concerta also provides a sustained 10-12 hour effect, allowing for once-daily dosing. ... The MLRTM release system allows for a sustained effect for 10-12 hours, allowing for once-daily dosing ... and working memory. …
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … METHYLPHENIDAT 1A PHAR10MG ... METHYLPHENIDAT HCL 1A 18MG ... METHYLPHENIDAT HCL 1A 36MG …
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORI 1A PHARMA 30MG ... ETORI 1A PHARMA 60MG ... ETORI 1A PHARMA 90MG …
Experimental
Matched Name: … (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE …
Matched Iupac: … (5Z)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …
Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Matched Synonyms: … Anti-COVID-19 hyperimmune globulin (human) ... Human plasma-derived immune-globulin for Coronavirus …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (9Z,12Z,15Z)-Octadecatrienoic acid ... 9-cis,12-cis,15-cis-octadecatrienoic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. …
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Synonyms: … Allogeneic donor CD362 enriched human umbilical cord-derived mesenchymal stromal cells …
Matched Name: … Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells …
Matched Description: … The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one ... mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and ... adult mesenchymal stem cells (MSCs); this feature allows them to be hypoimmunogenic and non-inducible …
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … as [clozapine] and [olanzapine]. ... , quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Receptor Antagonists …
Matched Products: … QUETIAPIN 1A PHARMA 25MG ... QUETIAPIN 1A PHARMA 50MG ... QUETIAPIN 1A PHARMA 100MG …
Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Description: … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa ... , as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Apixaban 1A Pharma 5 mg – Filmtabletten ... Apixaban 1A Pharma 2,5 mg – Filmtabletten …
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … N-(gamma-Dimethylaminopropyl)iminodibenzyl …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Tertiary amine TCAs, such as imipramine and amitriptyline, are more potent inhibitors of serotonin reuptake …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Modulators …
Investigational
Matched Synonyms: … Immunoglobulin G1 [121-(4-acetylphenylalanine),de-450-lysine], anti-(human epidermal growth factor receptor ... gamma1 heavy chain humanized (1-449) [VH humanized (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 ... (pAF) (121), K120 (217) (121- 218), hinge 1-15 (219 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … (9Z,12Z)-Octadecadienoic acid ... 9Z,12Z-octadecadienoic acid ... 9-cis,12-cis-Octadecadienoic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein …
Matched Description: … benefits of prolonged therapeutic efficacy, less frequent intravenous injections for patient convenience and ... blood disorder with an incidence of approximately once every 30,000 male births in all populations and ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … Live-attenuated Listeria monocytogenes actA/inlB/human mesothelin (hMeso) Strain hMeso38 …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN 1A PHARMA 125MG ... BOSENTAN 1A PHARMA 62.5MG ... ซิลเคย์ 125
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... regulation of kidney, vascular, and cardiac functions. …
Matched Mixtures name: … VALSARTAN 1A PLUS 80/12.5 ... VALSARTAN 1A PLUS 80/12.5 ... VALSARTAN 1A PLUS 80/12.5
Matched Categories: … Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren …
Matched Products: … Valsartan Reddy 120 mg Filmtabletten ... VALSARTAN 1A PHARMA 40MG ... VALSARTAN 1A PHARMA 80MG …
Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-programmed cell death protein 1 (PDCD1) (humanized clone ABT1 gamma4-chain), …
Matched Description: … those of the skin, lung, kidneys, and liver. ... [L33320] PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - ... [A234379] Agents acting on the PD-1 pathway, such as [nivolumab] and [pembrolizumab], facilitate endogenous …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Synonyms: … Bis(gamma-phenylpropyl)ethylamine …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin Agents ... Serotonin Receptor Antagonists ... Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists …
Investigational
Matched Synonyms: … Virulizin-2.gamma. …
Matched Categories: … Fluids and Secretions …
Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Approved
Vet approved
Matched Description: … is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and ... which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. ... Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug …
Matched Mixtures name: … TEXEF PLUS 200/125 MG FILM KAPLI TABLET, 20 ADET …
Matched Products: … CEFPODOXIM 1A PHAR40MG/5ML ... CEFPODOXIM 1A PHARMA 100MG ... CEFPODOXIM 1A PHARMA 200MG …
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Description: … It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic ... effects in movement disorders are not well understood but probably reflect an increase in synthesis and
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … AMANTADIN 100 1A PHARMA …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... amine TCAs, such as nortriptyline and desipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Serotonin Agents ... Serotonin Modulators ... Serotonin Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists …
Matched Products: … CLOMIPRAMIN 1A PHARMA 75MG …
Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Description: … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network ... oral ingestion of certain medications or poisons by absorbing most drugs and toxins. ... of pores, producing a material with large surface area and high affinity for various substances. …
Matched Mixtures name: … INTESTAL ENTERIK KAPLI ,120 DRAJE ... İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 120 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Humco Charcoal Activated ... NORIT TABLET 125 mg …
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Displaying drugs 1201 - 1225 of 1372 in total