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Displaying drugs 101 - 125 of 657 in total
SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …
PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Investigational
Matched Synonyms: … Inositol, hexakis(dihydrogen phosphate) hexasodium salt, myo- ... Myo-inositol, hexakis(dihydrogen phosphate), hexasodium salt ... (1r,2r,3s,4s,5r,6s)-cyclohexane-1,2,3,4,5,6-hexayl-hexakis(dihydrogen phosphate) …
Matched Iupac: … hexasodium (1R,2R,3S,4R,5s,6S)-2,3,4,5,6-pentakis(hydrogen phosphonatooxy)cyclohexyl hydrogen phosphate
Matched Categories: … Sugar Phosphates ... Inositol Phosphates
FM-VP4, is a novel hydrophilic phytostanol analogue representing a new class in cholesterol-lowering drugs called cholesterol absorption inhibitors. FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total cholesterol in a broad range of animal species. Additional experiments suggest that FM-VP4 can reduce plasma LDL...
Investigational
Matched Synonyms: … Disodium ascorbyl phytostanol phosphates
Matched Description: … FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total ... levels, reduce weight gain and exert a anti-atherosclerosis effect. ... Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride …
Experimental
Matched Synonyms: … Pantothenate phosphate ... D-pantothenic acid 4'-phosphate ... Pantothenic acid, 4'-(dihydrogen phosphate) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C. As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and...
Investigational
Matched Synonyms: … Meningococcal polysaccharide vaccine groups B and C …
Matched Description: … VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide ... Y, this vaccine was created for use against serogroups B and C. …
Experimental
Matched Synonyms: … Xylitol 5-phosphate
Matched Name: … L-xylitol 5-phosphate
Matched Categories: … Sugar Phosphates
Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Approved
Matched Synonyms: … Disodium glycerol phosphate
Matched Description: … Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. ... It is used clinically to treat or prevent low phosphate levels [FDA Label]. …
Matched Mixtures name: … Vitamin and Mineral Supplement - Liq ... Hemarexin Liquid and Drinkable Ampoules …
Matched Categories: … Phosphate salts ... Sugar Phosphates ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Matched Name: … Tedizolid phosphate
Matched Description: … Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate ... ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and
Experimental
Matched Synonyms: … 1,3-Hydroxy-2-propyl dihydrogen phosphate ... 1,2,3-Propanetriol, 2-(dihydrogen phosphate) …
Matched Name: … Glycerol 2-phosphate
Matched Categories: … Sugar Phosphates
Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Description: … and electrolyte disturbances. ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and
Experimental
Matched Synonyms: … Erythose-4-phosphate
Matched Name: … D-erythrose 4-phosphate
CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Investigational
Matched Synonyms: … Human CD24 and human IgG Fc Fusion Protein …
Investigational
Matched Synonyms: … Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … bendroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bendroflumethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Experimental
Matched Synonyms: … Guanosine 3'-(dihydrogen phosphate) 5'-(trihydrogen diphosphate) …
Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate
Matched Name: … alpha-D-mannose 6-phosphate
Investigational
Matched Synonyms: … Recombinant antibody construct against human CD30 and CD16A …
Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Matched Synonyms: … Calcium phosphates
Matched Name: … Calcium Phosphate
Matched Iupac: … tricalcium diphosphate …
Matched Description: … Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Multiple Vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Salts name: … Calcium phosphate, dibasic ... Calcium phosphate, tribasic …
Matched Categories: … Phosphate salts ... calcium phosphate ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Name: … Ascorbyl phosphate
Matched Description: … ascorbyl phosphate and sodium ascorbyl phosphate. ... Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate
Matched Categories: … Vitamin C and analogues …
Investigational
Matched Synonyms: … NKG2D on natural killer (NK) and cytotoxic T-cells ... Heterodimeric multi-specific IgG1 antibody targeting human epidermal growth factor receptor 2 (HER2) and
Experimental
Matched Name: … Paratoulene phosphate
Matched Categories: … Amino Acids, Peptides, and Proteins …
5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Experimental
Matched Synonyms: … Thymidine 5'-phosphate ... Thymidine-5'-phosphate ... thymidine 5'-(dihydrogen phosphate) …
Matched Description: … A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Synonyms: … D-glycerate 2-phosphate
Displaying drugs 101 - 125 of 657 in total