Displaying drugs 12676 - 12700 of 15488 in total
LIC-477
LIC-477is indicated to be suitable for the treatment of psychosomatic disturbances, epilepsy, trigeminal neuralgia and cerebral spasticity.
Investigational
Matched Description: … indicated to be suitable for the treatment of psychosomatic disturbances, epilepsy, trigeminal neuralgia and …
EP0057
EP0057 is a conjugate of Insert's proprietary drug delivery molecule, Cyclosert, and the potent anti-cancer compound camptothecin.
Investigational
Matched Description: … EP0057 is a conjugate of Insert's proprietary drug delivery molecule, Cyclosert, and the potent anti-cancer …
AZD-4877
AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
Investigational
Matched Iupac: … N-(3-aminopropyl)-N-(1-{5-benzyl-3-methyl-4-oxo-4H,5H-[1,2]thiazolo[5,4-d]pyrimidin-6-yl}-2-methylpropyl …
Matched Description: … AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms …
Matched Description: … AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms …
GMI-1359
GMI-1359 is a small molecule, glycomimetic compound with dual inhibitory activity against E-selectin and CXCR4.
Investigational
Matched Description: … GMI-1359 is a small molecule, glycomimetic compound with dual inhibitory activity against E-selectin and …
DengueCide
DengueCide is a nonjugate of a dengue virus specific small chemical ligand and an amphiphilic PEG based polymer
Investigational
Matched Description: … DengueCide is a nonjugate of a dengue virus specific small chemical ligand and an amphiphilic PEG based …
Nelmastobart
Nelmastobart is under investigation in clinical trial NCT05990543 (Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer).
Investigational
Matched Description: … Nelmastobart is under investigation in clinical trial NCT05990543 (Combination of Nelmastobart and Capecitabine …
Putrescine
Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more than one amine group. Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.
Experimental
Matched Description: … Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine ... drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and …
Quaternium-18
Quaternium-18 is a mixture of quaternary ammonium chloride salts. Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays. These compounds are poorly absorbed through the skin. Acute oral and percutaneous toxicity tests in animals indicate that they exhibit little or no systemic toxic effects.
Experimental
Matched Description: … Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays. ... Acute oral and percutaneous toxicity tests in animals indicate that they exhibit little or no systemic …
Phosphorus P-32
Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.
Experimental
Matched Description: … Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular ... water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular …
4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE
Experimental
Matched Iupac: … 4-[(3aS,4R,7R,8aS,8bR)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-7-hydroxy-1,3-dioxo-decahydropyrrolo[3,4-a …
NOX-700
NOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin. Immunohistochemical studies on
pancreatic tissue also showed that...
Investigational
Matched Description: … In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage ... studies on
pancreatic tissue also showed that NOX-700 therapy effectively preserved islet structure and ... It has since been found that oxidative signaling of the redox-sensitive transcription factor, NF-κB, and …
GSK-923295
GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline (GSK). GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of...
Investigational
Matched Description: … 923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and ... range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and ... -923295 is the first drug candidate to enter human clinical trials that specifically targets CENP-E and …
CYC116
CYC116 is a novel anticancer compound with a unique target profile involving both cell cycle and angiogenesis inhibition mechanisms. In preclinical studies, CYC116 has demonstrated antitumor activity in both solid tumors and hematological cancers.
Cyclacel's small molecule investigational drug, CYC116, is the third orally-available Cyclacel drug to enter development, which...
Investigational
Matched Description: … CYC116 is a novel anticancer compound with a unique target profile involving both cell cycle and angiogenesis ... In preclinical studies, CYC116 has demonstrated antitumor activity in both solid tumors and hematological …
NOX-100
NOX-100 is the new nitric oxide (NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and potential as a therapeutic to treat hemorrhagic shock. NOX-100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and inactivate NO, a simple...
Investigational
Matched Description: … NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and ... 100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and …
Zanidatamab zovodotin
According to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as ZW25 but armed with a cytotoxic payload." It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to...
Investigational
Matched Description: … It is being investigated for several indications characterized by HER2 expression including breast and ... gastric cancers that have progressed or are refractory to existing HER2-targeted therapies, and other …
MUC1 Dendritic Cell Vaccine
Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign...
Investigational
Matched Description: … Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the ... actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. ... The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign …
Inhibitor of P38 Kinase
Inhibitor of P38 Kinase is a solid. This compound belongs to the indoles. These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. This drug is known to target mitogen-activated protein kinase 14.
Experimental
(S)-2-Tetrahydrofuroic acid
Experimental
2-(3-OXO-PROPYLSULFANYLCARBONYL)-ETHANETHIOLATE
Experimental
1-Naphthoxyacetic acid
Experimental
Ractopamine
Vet approved
Displaying drugs 12676 - 12700 of 15488 in total