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Displaying drugs 1251 - 1275 of 1817 in total
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... is cleaved to form plasmin - also known as [fibrinolysin] - as part of the fibrinolytic pathway that breaks ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN ENDOGLIN (CD105 ANTIGEN)) HUMAN MOUSE CHIMERIC MONOCLONAL ANTIBODY ... Chimeric anti-CD105 antibody ... IMMUNOGLOBULIN G1, ANTI-(HUMAN ENDOGLIN) (HUMAN-MUS MUSCULUS MONOCLONAL TRC105 HEAVY CHAIN), DISULFIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate human
Matched Description: … VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. ... thrombosis and purpura fulminans. ... generation and intravascular clot formation. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Rosa centifolia flower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … Queens Rose Recovery Sheet Mask …
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … Exa-cel ... Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR …
Matched Description: … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor ... cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... progressive multi-organ damage, and premature death. …
Matched Categories: … Blood and Blood Forming Organs ... Autologous Cultured Cell
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with ... human monoclonal light chain, dimer …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
Experimental
Matched Synonyms: … Gold leaf
Matched Description: … A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. ... It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. …
Matched Categories: … Cell-mediated Immunity …
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Description: … Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted ... amounts of carene, camphene, dipentene, and terpinolene. ... It is used as a solvent and base material in organic synthesis reactions. …
Matched Mixtures name: … Half and Half Balm ... Jack and Jill Rub ... Chan Yat Hing She Kun Wool Lok Medicated Oil …
Matched Products: … Humco Turpentine Oil Rectified …
Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by Haemophilus influenzae type b. H. influenzae is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis. The vaccine contains the Haemophilus...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate …
Matched Name: … Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … The toxoid antigen is purified and toxin-inactivated. ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is …
Investigational
Matched Synonyms: … Allogeneic ex vivo expanded umbilical cord blood cells
Investigational
Matched Synonyms: … Allogeneic gene edited BCMA-directed CAR T cells
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Synonyms: … Recombinant human mannan-binding protein ... Recombinant human mannose-binding lectin …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections ... MBL forms different oligomers but must form at least a tetramer to be active. …
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … AUTOLOGOUS CD34+ CELLS ISOLATED FROM BONE MARROW OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY ... ) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING CODON-OPTIMIZED HUMAN
Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Description: … Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant ... Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. ... It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Products: … Sallys Box Friendly Black Head Three Step Sheet
Investigational
Matched Synonyms: … Maytansine, n2-deacetyl-n2-(3-mercapto-1-oxopropyl)-, conjugated humanized c242 monoclonal antibody ... N2'-deacetyl-n2'-(3-mercapto-1-oxopropyl)-maytansine -conjugated humanized c242 monoclonal antibody ... Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Synonyms: … liso-cel
Matched Description: … autoleucel] and [axicabtagene ciloleucel]. ... [A228493] Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval ... [L31588] CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... CD19-Directed Genetically Modified Autologous T-cell Immunotherapies …
Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human trail-r1) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy …
Matched Description: … Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human
Investigational
Matched Synonyms: … Recombinant human alpha 1-antitrypsin ... Recombinant human alpha 1-antitrypsin (raat) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … adenovirus vaccine encoding reduced expression in immortalized cell protein …
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with ... human monoclonal medi2070 .lambda. …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …
Investigational
Matched Synonyms: … Human T-cell receptor (BV5S2)peptide …
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Synonyms: … ), disulfide with human monoclonal js002 .kappa. ... apoptosis-regulated convertase 1, narc1, narc-1, proprotein convertase 9, pc9)), humanized monoclonal antibody ... Immunoglobulin g4, anti-(neural apoptosis-regulated convertase 1) (human monoclonal js002 .gamma.4-chain …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and
Displaying drugs 1251 - 1275 of 1817 in total