Displaying drugs 12801 - 12825 of 13422 in total
PF-06815345
PF-06815345 is under investigation in clinical trial NCT02654899 (Single Dose Study of PF-06815345 in Healthy Subjects).
Investigational
Matched Iupac: … (1S)-1-[5-(4-{4-[(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl]-2-fluorophenyl}-1-methyl-1H-pyrazol ... -5-yl)-1H-1,2,3,4-tetrazol-1-yl]ethyl ethyl carbonate …
PF-04634817
PF-04634817 is under investigation in clinical trial NCT01140672 (A Multiple Dose Study To Determine Safety, Tolerability, and Pharmacokinetics Of PF-04634817 In Healthy Adult Subjects).
Investigational
Matched Iupac: … (3S,4S)-3-methoxy-N-[(1R,3S)-3-(propan-2-yl)-3-[(1S,4S)-5-[6-(trifluoromethyl)pyrimidin-4-yl]-2,5-diazabicyclo ... [2.2.1]heptane-2-carbonyl]cyclopentyl]oxan-4-amine …
Matched Description: … PF-04634817 is under investigation in clinical trial NCT01140672 (A Multiple Dose Study To Determine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … PF-04634817 is under investigation in clinical trial NCT01140672 (A Multiple Dose Study To Determine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(S)-Hmg-Coa
Experimental
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-2-hydroxy-3,3-dimethyl-1-oxidobutylidene ... ]amino}-1-oxidopropylidene)amino]ethyl}sulfanyl)-3-hydroxy-3-methyl-5-oxopentanoate ... (3S)-5-({2-[(3-{[(2R)-4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan …
Triacetylchitotriose
Experimental
Matched Synonyms: … β-N,N',N''-triacetylchitotriose ... N,N',N''-triacetyl chitotriose β-anomer …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6S)-5-acetamido-6-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2 ... -(hydroxymethyl)oxan-3-yl]oxy}-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl ... )oxan-3-yl]acetamide …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6S)-5-acetamido-6-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2 ... -(hydroxymethyl)oxan-3-yl]oxy}-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl ... )oxan-3-yl]acetamide …
Iodine (131I) norcholesterol
Experimental
Matched Iupac: … ^{2,7}.0^{11,15}]heptadec-2(7)-en-5-ol ... (1S,5S,8R,10S,11S,14R,15R)-8-[(¹³¹I)iodomethyl]-15-methyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0 …
KOS-1584
KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Investigational
Matched Iupac: … prop-1-en-2-yl]-1-oxacyclohexadeca-10,13-diene-2,6-dione ... (4S,7R,8S,9S,10E,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl) …
Matched Description: … KOS-1584 is a second-generation epothilone. ... Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity ... KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease …
Matched Description: … KOS-1584 is a second-generation epothilone. ... Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity ... KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease …
Namitecan
Namitecan has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … ^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione ... (19S)-10-[(1E)-[(2-aminoethoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0 …
PL-3994
PL-3994 is under investigation in clinical trial NCT01304628 (Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma).
Investigational
Matched Iupac: … )-4-{[(2S)-1-[(2S,5R)-2-(3-carbamimidamidopropyl)-5-carbamoyl-3-oxopiperazin-1-yl]-3-(4-hydroxyphenyl ... )-1-oxopropan-2-yl]carbamoyl}-37-heptanamido-7-(hydroxymethyl)-34-[(1H-imidazol-4-yl)methyl]-28-methyl ... 2-[(4R,7S,10S,13S,16S,19R,22S,28R,31S,34S,37S)-31-benzyl-10-[(2S)-butan-2-yl]-19-butyl-13,22-bis(3-carbamimidamidopropyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Avilamycin
Vet approved
Matched Iupac: … ,6'R,7R,7'S,7aR,7'aR)-7'-acetyl-6'-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-2'H,3aH-2,4'-spirobi[[ ... 1,3]dioxolo[4,5-c]pyran]-7'-oloxy]-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl]oxy}-3-hydroxy-5-methoxy ... methyloxan-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate ... (2R,3S,4R,6S)-6-[(3aR,4R,4'R,5'S,6S,6'R,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR ... oxy}-4,6',7a-trimethyl-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxan]-4'-oloxy]-4-hydroxy-2- …
Ipatasertib
Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Investigational
Matched Iupac: … -1-yl}-3-[(propan-2-yl)amino]propan-1-one ... (2S)-2-(4-chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl]piperazin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fluorofuranylnorprogesterone F-18
Fluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).
Investigational
Matched Iupac: … (1R,2S,4R,6R,8S,9S,12S,13R)-8-[2-(¹⁸F)fluoroacetyl]-6-(furan-2-yl)-9-methyl-5,7-dioxapentacyclo[10.8.0.0 …
JAB-3068
Investigational
Matched Iupac: … 1-[4-({3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl}sulfanyl)-3,3-difluoro-2,3 ... -dihydro-1H-indol-1-yl]ethan-1-one …
Nicotinamide-adenine-dinucleotide-5-hydroxy-4-oxonorvaline
Experimental
Matched Iupac: … ]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium ... 4-[(1S,4S)-4-amino-4-carboxy-1-hydroxy-2-oxobutyl]-1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino ... -9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl …
Aprindine
Aprindine is a cardiac depressant used in arrhythmias.
Experimental
Matched Iupac: … N-[3-(diethylamino)propyl]-N-phenyl-2,3-dihydro-1H-inden-2-amine …
Matched Description: … Aprindine is a cardiac depressant used in arrhythmias. …
Matched Description: … Aprindine is a cardiac depressant used in arrhythmias. …
α-Methylfentanyl
α-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
Illicit
Matched Iupac: … N-phenyl-N-[1-(1-phenylpropan-2-yl)piperidin-4-yl]propanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4R-Fluoro-N6-ethanimidoyl-L-lysine
Experimental
Matched Iupac: … (2S,4S)-2-amino-6-[(E)-(1-aminoethylidene)amino]-4-fluorohexanoic acid …
D-gluconhydroximo-1,5-lactam
Experimental
Matched Iupac: … (2R,3R,4S,5S)-6-(hydroxyamino)-2-(hydroxymethyl)-2,3,4,5-tetrahydropyridine-3,4,5-triol …
L-Alpha-Glycerophosphorylserine
Experimental
Matched Iupac: … (2S)-2-amino-3-({[(2R)-2,3-dihydroxypropoxy](hydroxy)phosphoryl}oxy)propanoic acid …
Quinonoid 7,8-Tetrahydrobiopterin
Experimental
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,6,7-tetrahydropteridin-4-one …
O1-Pentyl-Mannose
Experimental
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(pentyloxy)oxane-3,4,5-triol …
4-Nitrophenyl-Ara
Experimental
Matched Iupac: … (2S,3R,4R,5S)-2-(hydroxymethyl)-5-(4-nitrophenoxy)oxolane-3,4-diol …
5-fluorotryptophan
5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid …
1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
Matched Iupac: … 2-{[(2R,3S,4R)-2,3,4-trihydroxy-5-(phosphonooxy)pentyl]amino}benzoic acid …
Matched Iupac: … 2-{[(2R,3S,4R)-2,3,4-trihydroxy-5-(phosphonooxy)pentyl]amino}benzoic acid …
Gallium maltolate
Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.
Investigational
Matched Iupac: … gallium(3+) ion tris(2-methyl-4-oxo-4H-pyran-3-olate) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pegnivacogin
Investigational
Matched Iupac: … ({6-[2,6-bis({[(2-methoxyethoxy)carbonyl]amino})hexanamido]hexyl}oxy)phosphonic acid …
Displaying drugs 12801 - 12825 of 13422 in total