Displaying drugs 13301 - 13325 of 13804 in total
MK-4830
MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT) 4 receptor.
Investigational
Matched Description: … MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT …
TLY-012
TLY-012 is a PEGylated recombinant human tumor necrosis factor-related apoptosis-inducing ligand (PEGylated TRAIL).
Investigational
Matched Description: … TLY-012 is a PEGylated recombinant human tumor necrosis factor-related apoptosis-inducing ligand (PEGylated …
IDUA-RTB
RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB).
Investigational
Matched Description: … RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB). …
Calpurbatug
Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates bacterial biofilm.
Investigational
Matched Description: … Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates …
Surotomycin
Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections. Surotomycin has a fourfold greater in vitro potency than vancomycin against C. Difficile and other...
Investigational
Matched Iupac: … -decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl ... (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21 ... -2-[(2S)-3-(1H-indol-3-yl)-2-[(2E)-3-(4-pentylphenyl)but-2-enamido]propanamido]propanamido]propanoic ... -bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29 …
Matched Description: … Surotomycin has a fourfold greater in vitro potency than vancomycin against C. ... It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents ... effective against both initial and relapsing hamster Clostridium difficile-associated diarrhea, with a …
Matched Description: … Surotomycin has a fourfold greater in vitro potency than vancomycin against C. ... It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents ... effective against both initial and relapsing hamster Clostridium difficile-associated diarrhea, with a …
Inhibitor of P38 Kinase
Inhibitor of P38 Kinase is a solid. This compound belongs to the indoles. These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. This drug is known to target mitogen-activated protein kinase 14.
Experimental
Matched Iupac: … 3-[2-(pyridin-4-yl)ethyl]-1H-indole …
Matched Description: … Inhibitor of P38 Kinase is a solid. This compound belongs to the indoles. ... These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to …
Matched Description: … Inhibitor of P38 Kinase is a solid. This compound belongs to the indoles. ... These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to …
Filaminast
Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Experimental
Matched Iupac: … (E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylidene}amino carbamate …
Matched Description: … Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). …
Matched Description: … Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). …
Porfiromycin
Porfiromycin is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anticancer antibiotics.
Investigational
Matched Iupac: … ,8S)-11-amino-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca-1( …
Matched Description: … Porfiromycin is a substance that is being studied in the treatment of cancer. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Porfiromycin is a substance that is being studied in the treatment of cancer. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Diridavumab
Cr6261 is under investigation in clinical trial NCT02016066 (A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of Diridavumab in Japanese Healthy Participants).
Investigational
Matched Description: … Cr6261 is under investigation in clinical trial NCT02016066 (A Study to Assess the Safety, Pharmacokinetics …
Bixalomer
Bixalomer is under investigation in clinical trial NCT01115985 (A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers).
Investigational
Matched Description: … Bixalomer is under investigation in clinical trial NCT01115985 (A Study to Assess the Effect of ASP1585 …
Orilanolimab
Orilanolimab is under investigation in clinical trial NCT03075878 (A Safety Study of SYNT001 in Subjects With Chronic, Stable Warm Autoimmune Hemolytic Anemia (WAIHA)).
Investigational
Matched Description: … Orilanolimab is under investigation in clinical trial NCT03075878 (A Safety Study of SYNT001 in Subjects …
Imsidolimab
Imsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis).
Investigational
Matched Description: … Imsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and …
FLT201
FLT201 is a recombinant adeno-associated viral vector serotype S3 containing codon optimised expression cassette encoding human beta (β)-glucocerebrosidase variant 85 (GCasevar85)
Investigational
Matched Description: … FLT201 is a recombinant adeno-associated viral vector serotype S3 containing codon optimised expression …
BREN-02
BREN-02 is a recombinant human homeoprotein Engrailed 1 (rhEN1).
Investigational
Matched Description: … BREN-02 is a recombinant human homeoprotein Engrailed 1 (rhEN1). …
CALY-002
CALY-002 is a humanized monoclonal antibody targeting interleukin-15.
Investigational
Matched Description: … CALY-002 is a humanized monoclonal antibody targeting interleukin-15. …
BBP-671
BBP-671 is a small molecule activator of pantothenate kinases.
Investigational
Matched Description: … BBP-671 is a small molecule activator of pantothenate kinases. …
Vasomera
Investigational
D-Levofloxacin
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Experimental
Matched Iupac: … (2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5,7,9 …
Matched Description: … A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity …
Matched Description: … A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity …
Icosabutate
Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study).
Investigational
Matched Iupac: … 2-[(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaen-1-yloxy]butanoic acid …
Matched Description: … Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption …
Matched Description: … Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption …
Cloprednol
Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
Experimental
Matched Iupac: … (1S,2R,10S,11S,14R,15S,17S)-8-chloro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0 …
Matched Description: … Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma …
Matched Description: … Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma …
RO-5045337
RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With Solid Tumors).
Investigational
Matched Iupac: … -1-carbonyl]-4-(3-methanesulfonylpropyl)piperazine ... 1-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole …
Matched Description: … RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With …
Matched Description: … RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With …
Frovocimab
Frovocimab is under investigation in clinical trial NCT01671085 (A Study of LY3015014 in Healthy Participants With High Cholesterol).
Investigational
Matched Description: … Frovocimab is under investigation in clinical trial NCT01671085 (A Study of LY3015014 in Healthy Participants …
LY2828360
LY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With Osteoarthritic Knee Pain).
Investigational
Matched Iupac: … 8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)-9H-purine …
Matched Description: … LY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … LY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
ENB-003
ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.
Investigational
Matched Description: … ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for …
MORAb-066
MORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.
Investigational
Matched Description: … MORAb-066 is a humanized antibody directed against tissue factor (TF). …
Displaying drugs 13301 - 13325 of 13804 in total