Displaying drugs 13376 - 13400 of 14095 in total
Allocetra
Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune system without immune system suppression. With infusion, the body's macrophages and dendritic cells can feed on these early apoptotic...
Investigational
Matched Description: … body's macrophages and dendritic cells can feed on these early apoptotic Allocetra cells and thus result in ... Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream ... of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune system …
Bifenthrin
Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).
Investigational
Matched Iupac: … {2-methyl-[1,1'-biphenyl]-3-yl}methyl (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane …
Matched Description: … Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic ... Stroke Management in Europe Observational Registry). …
Matched Description: … Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic ... Stroke Management in Europe Observational Registry). …
MUL001
MUL001 is live attenuated strain of Salmonella typhimurium being investigated for the treatment of schwannomas.
Investigational
Matched Description: … MUL001 is live attenuated strain of _Salmonella typhimurium_ being investigated for the treatment of …
Merimepodib
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Investigational
Matched Description: … lymphocytes at concentrations of approximately 100 nM. ... Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. ... Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog …
Darusentan
Darusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Investigational
Matched Iupac: … (2S)-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Pagoclone
Pagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with...
Investigational
Matched Iupac: … 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-2,3-dihydro-1H-isoindol-1-one …
Matched Description: … It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Norgestomet
Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin used in veterinary medicine to control estrus and ovulation in cattle.
Vet approved
Matched Description: … veterinary medicine to control estrus and ovulation in cattle. ... Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin used in …
Cefilavancin
Cefilavancin is a covalently-linked glycopeptide-cephalosporin (beta-lactam) heterodimer antibiotic that exhibits substantially greater activity than its component parts against Gram-positive bacteria.
Investigational
Matched Iupac: … {[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-[(3-{[(1S,2R,18R,19R,22S,25R,28R,40S)-48- ... )oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino ... carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... )pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RPI-78M
RPI-78M is being developed for the treatment of multiple sclerosis (MS). Other neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).
Investigational
Matched Description: … RPI-78M is being developed for the treatment of multiple sclerosis (MS). …
IPH 1101
IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens which specifically activate the Vγ9Vδ2 T cell subset. IPH 1101 is the most advanced drug candidate of the γδ T cell platform
Investigational
Matched Description: … IPH 1101 is the most advanced drug candidate of the γδ T cell platform ... IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens …
APR-548
APR-548 is an analog of eprenetapopt and a reactivator of mutant p53.
Investigational
Matched Description: … APR-548 is an analog of [eprenetapopt] and a reactivator of mutant p53. …
Volrustomig
Volrustomig is under investigation in clinical trial NCT06097728 (MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma).
Investigational
Matched Description: … Volrustomig is under investigation in clinical trial NCT06097728 (MEDI5752 in Combination With Carboplatin ... Plus Pemetrexed in Unresectable Pleural Mesothelioma). …
5alpha-androstane-3beta,17alpha-diol
5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Experimental
Matched Description: … of [testosterone] with androgenic activity. ... It has been implicated as a regulator of gonadotropin secretion. ... 5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite …
PR1 leukemia peptide vaccine
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Description: … GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome). ... PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
CSL324
CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques. It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease, rheumatoid arthritis, and vasculitis.
Investigational
Matched Description: … a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in ... [A225626] It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory …
Demcizumab
Demcizumab is under investigation for the treatment of Nonsquamous Nonsmall Cell Neoplasm of Lung.
Investigational
Matched Description: … Demcizumab is under investigation for the treatment of Nonsquamous Nonsmall Cell Neoplasm of Lung. …
P54
P54 reduces the inflammation associated with cancer/tumors, Crohn's disease, inflammatory bowel disease, osteoarthritis, and ulcerative colitis. It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Investigational
Matched Description: … It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as …
Larazotide
An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
Investigational
Matched Iupac: … 2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-3-methylbutanamido]-4-methylpentanamido ... ]-3-methylbutanamido]-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}acetic acid …
Matched Description: … occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease. ... An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula …
Matched Description: … occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease. ... An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula …
Fosdevirine
Investigational
Matched Iupac: … (S)-(methyl (2-carbamoyl-5-chloro-1H-indol-3-yl)({3-[(1E)-2-cyanoeth-1-en-1-yl]-5-methylphenyl})phosphinate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Capravirine
Investigational
Matched Iupac: … {5-[(3,5-dichlorophenyl)sulfanyl]-4-(propan-2-yl)-1-[(pyridin-4-yl)methyl]-1H-imidazol-2-yl}methyl carbamate …
Labetuzumab
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Description: … It is used in radioimmunotherapy. …
Telatinib
Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine/ Oxaliplatin in 1st Line Gastric or GEJ Cancer).
Investigational
Matched Iupac: … 4-[({4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methylpyridine-2-carboxamide …
Matched Description: … Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine ... / Oxaliplatin in 1st Line Gastric or GEJ Cancer). …
Matched Description: … Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine ... / Oxaliplatin in 1st Line Gastric or GEJ Cancer). …
Belapectin
Belapectin is under investigation in clinical trial NCT02575404 (GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients).
Investigational
Matched Description: … Belapectin is under investigation in clinical trial NCT02575404 (GR-MD-02 Plus Pembrolizumab in Melanoma …
IRX-5183
Investigational
Matched Iupac: … 4-(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-amido)-2,6-difluorobenzoic …
FK-960
Investigational
Displaying drugs 13376 - 13400 of 14095 in total