Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 13426 - 13450 of 13804 in total

Veliflapon

Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).
Investigational
Matched Iupac: … (2R)-2-cyclopentyl-2-{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid …
Matched Description: … clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Gevokizumab

Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. …

CR665

CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound. In addition, unlike currently marketed opioids, CR665 does...
Investigational
Matched Iupac: … (2R)-2-[(2R)-2-[(2R)-2-amino-3-phenylpropanamido]-3-phenylpropanamido]-N-[(1R)-4-carbamimidamido-1-{[ …
Matched Description: … Preclinical animal studies suggest that CR665 is a potent analgesic compound. ... CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid …

Fluocortin

Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain .
Experimental
Matched Iupac: … 2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl]-2-oxoacetic acid ... 2-[(1S,2R,8S,10S,11S,13R,14S,15S,17S)-8-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{ …
Matched Description: … Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain [A174817 …

Poseltinib

Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}furo[3,2-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide …
Matched Description: … Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

EXT608

EXT608 is a long-acting PTH derivative under investigation for the treatment of hyperparathyroidism.
Investigational
Matched Description: … EXT608 is a long-acting PTH derivative under investigation for the treatment of hyperparathyroidism. …

Cirazoline

Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent. Cirazoline has also been shown to decrease food...
Experimental
Matched Iupac: … 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … Cirazoline acts on a number of α adrenergic receptors. ... It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Agonists …

SCB-2019

SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
Matched Description: … SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID ... As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908 …

Relacatib

Investigational
Matched Iupac: … (2S)-2-[(1-benzofuran-2-yl)formamido]-4-methyl-N-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)azepan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-863233

BMS-863233 has been investigated for the treatment of Refractory Hematologic Cancer.
Investigational
Matched Iupac: … 12-chloro-4-[(2S)-pyrrolidin-2-yl]-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen …
Matched Salts cas: … 1169562-71-3 …

Ponazuril

Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Vet approved
Matched Iupac: … 1-methyl-3-[3-methyl-4-(4-trifluoromethanesulfonylphenoxy)phenyl]-1,3,5-triazinane-2,4,6-trione …
Matched Description: … Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(5E,7E,9)-decatrien-2-one

An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5Z,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Name: … (5E,7E,9)-decatrien-2-one …
Matched Iupac: … (5Z,7E)-deca-5,7,9-trien-2-one …
Matched Description: … Similar to [(5Z,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …

(5Z,7E,9)-decatrien-2-one

An compound produced by Fomitopsis betulina, an edible fungus commonly called the birch polypore. Similar to (5E,7E,9)-decatrien-2-one, it has a strong pineapple aroma.
Experimental
Matched Name: … (5Z,7E,9)-decatrien-2-one …
Matched Iupac: … (5E,7E)-deca-5,7,9-trien-2-one …
Matched Description: … Similar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116] …

2'-Fucosyllactose

2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Investigational
Matched Name: … 2'-Fucosyllactose …
Matched Iupac: … -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,3,5,6-tetrahydroxyhexanal ... (2R,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy …
Matched Description: … 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy). ... 2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of …

Survodutide

Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)).
Investigational
Matched Description: … Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide …

Robenacoxib

Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
Experimental
Vet approved
Matched Iupac: … 2-{5-ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]phenyl}acetic acid …
Matched Description: … Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …

Magnolia kobus flowering top

Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. …

Chlorotoxin

Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
Investigational
Matched Description: … Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous …

REC-994

REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Investigational
Matched Description: … REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous …

Orticumab

Orticumab is under investigation in clinical trial NCT04776629 (A Proof-of-activity Study With Orticumab in Subjects With Psoriasis and Cardiometabolic Risk Factors).
Investigational
Matched Description: … Orticumab is under investigation in clinical trial NCT04776629 (A Proof-of-activity Study With Orticumab …

Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection . It...
Investigational
Matched Name: … Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) …
Matched Description: … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding ... domain into a baculovirus expression system[F4738, A226853]. ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …

JB991

JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug...
Investigational
Matched Description: … JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. ... In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory …

5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole

5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. Known drug targets of 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole include genome polyprotein.
Experimental
Matched Name: … 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole …
Matched Iupac: … 5-{3-[2,6-dichloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]propyl}-3-methyl-1,2-oxazole …
Matched Description: … 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole is a solid. ... Known drug targets of 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole ... These are aromatic compounds containing an ether group substituted with a benzene ring. …

Flumequine

Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Withdrawn
Matched Iupac: … 7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid …
Matched Description: … Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Concizumab

Concizumab has been used in trials studying the treatment of Haemophilia A and Congenital Bleeding Disorder.
Investigational
Matched Description: … Concizumab has been used in trials studying the treatment of Haemophilia A and Congenital Bleeding Disorder …
Displaying drugs 13426 - 13450 of 13804 in total