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Displaying drugs 13601 - 13625 of 13784 in total

Sovleplenib

Sovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting spleen tyrosine kinase (Syk). It is under investigation in clinical trial NCT03483948 (Phase I Study of Hmpl-523+azacitidine in Elderly Patients With Acute Myeloid Leukemia).
Investigational
Matched Iupac: … 7-[4-(1-methanesulfonylpiperidin-4-yl)phenyl]-N-{[(2S)-morpholin-2-yl]methyl}pyrido[3,4-b]pyrazin-5-amine …
Matched Description: … Sovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting …

Safingol

Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S,3S)-2-aminooctadecane-1,3-diol …

Ecopipam

Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Omapatrilat

Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. This drug from BMS was not approved by the FDA due...
Investigational
Matched Iupac: … (4S,7S,10aS)-5-oxo-4-[(2S)-3-phenyl-2-sulfanylpropanamido]-octahydro-2H-pyrido[2,1-b][1,3]thiazepine- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

TNX-901

TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.
Investigational
Matched Description: … TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in …

Etofibrate

Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.
Experimental
Matched Iupac: … 2-(pyridine-3-carbonyloxy)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Matched Description: … Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. …

MK-3577

MK-3577 is under investigation in clinical trial NCT00868790 (A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)).
Investigational
Matched Iupac: … 3-({4-[(1R,2S)-1-(4-chlorophenyl)-1-(7-fluoro-5-methyl-1H-indol-3-yl)pentan-2-yl]phenyl}formamido)propanoic …
Matched Description: … -3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)). ... MK-3577 is under investigation in clinical trial NCT00868790 (A Study of the Safety and Efficacy of MK …

IDM-2

IDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells. IDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.
Investigational
Matched Name: … IDM-2 …
Matched Description: … IDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells. …

Sarpogrelate

Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.
Investigational
Matched Iupac: … 4-{[1-(dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}propan-2-yl]oxy}-4-oxobutanoic acid …
Matched Salts cas: … 135159-51-2 …

R450

R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Investigational
Matched Description: … R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. …

Sulfaquinoxaline

Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as potential treatment of coccidiosis.
Vet approved
Matched Iupac: … 4-amino-N-(quinoxalin-2-yl)benzene-1-sulfonamide …
Matched Description: … Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It …

Glucose-6-Phosphate

An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
Experimental
Matched Description: … It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6- …

BLX-883

BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide sales currently exceed $3 billion.
Investigational
Matched Description: … sales currently exceed $3 billion. ... BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. ... Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide …

Racivir

Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.
Investigational
Matched Iupac: … 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … Racivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Mibenratide

Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies).
Investigational
Matched Iupac: … -4,7-bis(3-carbamimidamidopropyl)-22-(2-carbamoylethyl)-52-(carbamoylmethyl)-16,31,49-tris(carboxymethyl ... 3-[(1R,4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R,40S,43S,49S,52S,55S)-40-(4-aminobutyl)-28-benzyl ... hydroxyphenyl)methyl]-10,19-dimethyl-3,6,9,12,15,18,21,24,27,30,33,36,39,42,48,51,54,57-octadecaoxo-25-(propan-2- …
Matched Description: … Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics …

Phelimin

Phelemin (PHE-MIP) is a methacrylic acid-based copolymer purified to bind to L-phenylalanine and L-phenylalanine-containing peptides. It is under investigation for the treatment of hyperphenylalaninemia.
Investigational
Matched Description: … Phelemin (PHE-MIP) is a methacrylic acid-based copolymer purified to bind to L-phenylalanine and L-phenylalanine-containing …

Galicaftor

Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis.).
Investigational
Matched Iupac: … -2H-1-benzopyran-2-yl]benzoic acid ... 4-[(2R,4R)-4-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-7-(difluoromethoxy)-3,4-dihydro …
Matched Description: … Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Cryptomeria japonica bark

Experimental

BMS-863233

BMS-863233 has been investigated for the treatment of Refractory Hematologic Cancer.
Investigational
Matched Iupac: … 12-chloro-4-[(2S)-pyrrolidin-2-yl]-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen …
Matched Salts cas: … 1169562-71-3 …

LX6171

LX6171 is an oral drug candidate that was generated by Lexicon medicinal chemists and is being developed to treat disorders characterized by cognitive impairment, such as Alzheimer's disease, schizophrenia or vascular dementia.
Investigational

Cefovecin

Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with dosing for the animal. It is used for the treatment of skin infections caused by Pasturella multocida in...
Experimental
Vet approved
Matched Iupac: … thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-3-[(2S)-oxolan-2-yl]-5- …
Matched Description: … Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. ... The advantage of using injectable antibiotics is not missing a dose that can allow partially resistant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

PS386113

PS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders. It is being developed by Schering-Plough and Pharmacopeia. Little information has been released about PS386113.
Investigational
Matched Description: … PS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders …

Deleobuvir

Deleobuvir is under investigation in clinical trial NCT01983566 (Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects).
Investigational
Matched Iupac: … (2E)-3-(2-{1-[2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-amido]cyclobutyl}-1-methyl ... -1H-1,3-benzodiazol-6-yl)prop-2-enoic acid …
Matched Description: … in clinical trial NCT01983566 (Effect of Food and Increased Gastric pH Value on Bioavailability of a …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

MK-2748

MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).
Investigational
Matched Iupac: … (1R,18R,22R,26S,29S)-26-cyclopentyl-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl} …
Matched Description: … MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety …

Tiragolumab

Tiragolumab is under investigation in clinical trial NCT04513925 (A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Tiragolumab is under investigation in clinical trial NCT04513925 (A Study of Atezolizumab and Tiragolumab …
Displaying drugs 13601 - 13625 of 13784 in total