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Displaying drugs 1351 - 1375 of 2793 in total
Experimental
Matched Synonyms: … Vitamin B 12 factor IIIm …
Matched Name: … Vitamin B 12 factor IIIm …
Experimental
Matched Name: … 12-Phenylheme …
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Name: … PX-12
Matched Description: … Initial trials correlated doses of Px-12 with increased patient survival. ... PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), ... Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated …
Investigational
Matched Name: … CP-12
Matched Iupac: … tetradecaoxo-1,4,10,13,16,19,22,25,28,31,34,37,40,43-tetradecaazatricyclo[43.3.0.0^{6,10}]octatetracontan-12
8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
Experimental
Matched Synonyms: … 8 AG ... Azaguanine-8
Matched Name: … 8-azaguanine …
Matched Description: … 8-azaguanine is one of the early purine analogs showing antineoplastic activity. …
Experimental
Matched Synonyms: … 8-Epicobalamine ... Cyano-8-epicobalamin …
Matched Name: … 8-epi-Cyanocobalamin …
Experimental
Matched Name: … Ro 12-7310 …
Experimental
Matched Synonyms: … 8-OH-Dgmp ... 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid ... 8-hydroxydeoxyguanosine 5'-monophosphate …
Matched Name: … 8-oxo-dGMP …
Experimental
Matched Synonyms: … 8-OHdG ... 8-Oxo-dG ... 8-Oxoguanosine …
Matched Name: … 8-hydroxy-2'-deoxyguanosine …
Matched Iupac: … 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Investigational
Matched Synonyms: … INTERLEUKIN 8 ... INTERLEUKIN 8 (HUMAN) …
Matched Name: … Human Interleukin 8
Matched Description: … Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes …
Matched Categories: … Interleukin-8, antagonists & inhibitors …
Experimental
Matched Name: … 12-Bromododecanoic Acid …
Matched Iupac: … 12-bromododecanoic acid …
Experimental
Matched Name: … 12-Hydroxydodecanoic Acid …
Matched Iupac: … 12-hydroxydodecanoic acid …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter …
Matched Name: … AAV2/8.TBG.hARSB …
Experimental
Matched Synonyms: … 1-Anilino-8-naphthalenesulfonate ... 1-anilino-8-naphthalenesulfonic acid ... 8-Anilino-1-naphthalene sulfonic acid …
Matched Name: … 8-anilinonaphthalene-1-sulfonic acid …
Matched Iupac: … 8-(phenylamino)naphthalene-1-sulfonic acid …
Experimental
Matched Name: … 8-azaxanthine …
Experimental
Matched Name: … (12R)-12-hydroxyeicosapentaenoic acid …
Matched Iupac: … (5Z,8Z,10E,12R,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid …
Experimental
Matched Name: … 12-Bromo-1-dodecanol …
Matched Iupac: … 12-bromododecan-1-ol …
Experimental
Matched Name: … 8-demethyl-8-dimethylamino-flavin-adenine-dinucleotide …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-[8-(dimethylamino …
Experimental
Matched Name: … 8-iodo-guanine …
Matched Iupac: … 2-amino-8-iodo-6,7-dihydro-3H-purin-6-one …
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized ... with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc. …
Experimental
Matched Synonyms: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate ... 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester …
Matched Name: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate …
Matched Iupac: … ethyl 3-(8-hydroxyquinolin-5-yl)-2-[(prop-2-yn-1-yl)amino]propanoate …
Experimental
Matched Name: … 8-Methyl-9-Oxoguanine …
Experimental
Matched Name: … TACRINE(8)-4-AMINOQUINOLINE …
Experimental
Matched Name: … methyl 4-bromo-N-[8-(hydroxyamino)-8-oxooctanoyl]-L-phenylalaninate …
Experimental
Matched Name: … 8-Bromoadenosine-5'-Diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Displaying drugs 1351 - 1375 of 2793 in total