Displaying drugs 1401 - 1425 of 2016 in total
Ersodetug
Investigational
Matched Synonyms: … Immunoglobulin G2, anti-(human insulin receptor) (human monoclonal RZ358 γ2-chain), disulfide with human ... immunoglobulin G2-kappa, anti-[Homo sapiens INSR (insulin receptor)], Homo sapiens monoclonal antibody …
Tridecactide
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human …
Matched Description: … stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. ... Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte …
Matched Description: … stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. ... Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte …
STX-100
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
Girentuximab
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AOC-1020
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector ... function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting ... , effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA …
Cosfroviximab
Investigational
Matched Synonyms: … ) (human-mus musculus monoclonal c13c6-fr1 heavy chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1, anti-(ebolavirus/reston ebolavirus/sudan ebolavirus/tai forest ebolavirus glycoprotein …
TCN-202
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
Alidornase alfa
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
Saruplase
Experimental
Matched Synonyms: … KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK33 REDUCED) ... PROUROKINASE (ENZYME ACTIVATING) (HUMAN CLONE PUK4/PUK18), NONGLYCOSYLATED ... PLASMINOGEN ACTIVATOR, PRO- (HUMAN LIVER UROKINASE-TYPE PROTEIN MOIETY REDUCED) …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
scAAV9.U7.ACCA
scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Synonyms: … target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA ... non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to …
Matched Description: … scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense ... sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding …
Matched Description: … scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense ... sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding …
Tuparstobart
Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Synonyms: … Immunoglobulin G1 [301-alanine,de-C-terminal-lysine], anti-(human lymphocyte activation gene-3 protein ... ) (human-Mus musculus monoclonal INCAGN02385 γ1-chain), disulfide with human-Mus musculus monoclonal ... immunoglobulin G1-kappa,anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223 …
Matched Description: … investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and ... Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and …
Matched Description: … investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and ... Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and …
AD-214
Investigational
Matched Synonyms: … 3 of the Fc region of a mutated human IgG1 ... Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and …
Pegzilarginase
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Nemvaleukin alfa
Investigational
Matched Synonyms: … -chain (human) ... 2 receptor α-chain (human) ... human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human …
Erzotabart
Erzotabart is under investigation in clinical trial NCT04824794 (GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-glycine), anti-(human cd38 antigen) (human monoclonal gen3014 .gamma.1-chain), ... disulfide with human monoclonal gen3014 .kappa. ... Immunoglobulin G1-kappa, anti-[Homo sapiens CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
Panobacumab
Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Synonyms: … Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa ... Human monoclonal antibody directed against serotype O1 Pseudomonas aeruginosa …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Synonyms: … Human anti-CD94 IgG1 monoclonal antibody (non-fucosylated) …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Elivaldogene tavalentivec
Investigational
Matched Synonyms: … A vsv-g*-pseudotyped self-inactivating hiv-1-derived lentiviral vector (plbp100 hald) encoding human ... Dna (lentiviral vector clone lenti-d human x-linked adrenoleukodystrophy abcd1 gene cdna-specifying) …
Porgaviximab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide ... with human-mus musculus monoclonal c2g4 .kappa. ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
Ad-RTS-hIL-12
Investigational
Matched Synonyms: … Adenoviral vector-RheoSwitch Therapeutic System-human interleukin 12 …
LV-FAH
Investigational
Matched Synonyms: … Lentiviral Vector Expressing Human Fumarylacetoacetate Hydrolase …
Displaying drugs 1401 - 1425 of 2016 in total