Displaying drugs 14826 - 14850 of 15697 in total
LX-7101
LX-7101 is under investigation in clinical trial NCT01528111 (Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension).
Investigational
Matched Iupac: … 3-[4-(aminomethyl)-1-{5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine-4-amido]phenyl N,N-dimethylcarbamate …
Matched Description: … , and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension). ... LX-7101 is under investigation in clinical trial NCT01528111 (Study to Evaluate the Safety, Tolerability …
Matched Description: … , and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension). ... LX-7101 is under investigation in clinical trial NCT01528111 (Study to Evaluate the Safety, Tolerability …
PF-06882961
PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl …
Matched Description: … and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus). ... PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy …
Matched Description: … and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus). ... PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy …
Benapenem
Benapenem is under investigation in clinical trial NCT04505683 (A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (Cuti) or Acute Pyelonephritis (AP)).
Investigational
Matched Description: … Benapenem is under investigation in clinical trial NCT04505683 (A Study to Assess Efficacy and Safety ... Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (Cuti) or Acute Pyelonephritis …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lorecivivint
Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease).
Investigational
Matched Iupac: … N-(5-{3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide …
Matched Description: … Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability ... , and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability ... , and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lulizumab pegol
Lulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome).
Investigational
Matched Description: … the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome). ... Lulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate …
MK-0773
MK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)).
Investigational
Matched Iupac: … (4aS,4bS,6aS,7S,9aS,9bS,11aR)-3-fluoro-N-({1H-imidazo[4,5-b]pyridin-2-yl}methyl)-1,4a,6a-trimethyl-2- ... oxo-1H,2H,4aH,4bH,5H,6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinoline-7-carboxamide …
Matched Description: … MK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK ... -0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)). …
Matched Description: … MK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK ... -0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)). …
Lifastuzumab vedotin
Lifastuzumab vedotin is under investigation in clinical trial NCT01363947 (Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum Resistant Ovarian Cancer).
Investigational
Matched Description: … Lifastuzumab vedotin is under investigation in clinical trial NCT01363947 (Safety and Pharmacokinetics ... of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum …
S-777469
S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).
Investigational
Matched Iupac: … 1-{6-ethyl-1-[(4-fluorophenyl)methyl]-5-methyl-2-oxo-1,2-dihydropyridine-3-amido}cyclohexane-1-carboxylic …
Matched Description: … the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis). ... S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate …
Matched Description: … the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis). ... S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate …
Posizolid
Posizolid (AZD2563) is an oxazolidinone antibiotic. In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though no results were reported).
Investigational
Matched Iupac: … -oxazol-3-yloxy)methyl]-1,3-oxazolidin-2-one ... (5R)-3-(4-{1-[(2S)-2,3-dihydroxypropanoyl]-1,2,3,6-tetrahydropyridin-4-yl}-3,5-difluorophenyl)-5-[(1,2 …
Matched Description: … In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were …
Matched Description: … In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were …
Danvatirsen
Danvatirsen is under investigation in clinical trial NCT03334617 (Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.).
Investigational
Matched Description: … Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.). ... Danvatirsen is under investigation in clinical trial NCT03334617 (Phase II Umbrella Study of Novel Anti-cancer …
GS-6620
GS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis C Virus Infection).
Investigational
Matched Iupac: … -4-methyl-3-[(2-methylpropanoyl)oxy]oxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate ... propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-4-hydroxy …
Matched Description: … GS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability ... C Virus Infection). ... , Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … GS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability ... C Virus Infection). ... , Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pexelizumab
Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Investigational
Matched Description: … Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. …
Pipazethate
A non-narcotic oral antitussive agent.
Experimental
Matched Iupac: … 2-[2-(piperidin-1-yl)ethoxy]ethyl 9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12 ... -hexaene-2-carboxylate …
Matched Description: … A non-narcotic oral antitussive agent. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … A non-narcotic oral antitussive agent. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Phenoxypropazine
Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging to the hydrazine chemical class. It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic potential.
Withdrawn
Matched Iupac: … (1-phenoxypropan-2-yl)hydrazine …
Matched Description: … It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic ... Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging …
Matched Description: … It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic ... Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging …
Retatrutide
Retatrutide is under investigation in clinical trial NCT06354660 (Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)).
Investigational
Matched Description: … Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise ... Retatrutide is under investigation in clinical trial NCT06354660 (Effect of Retatrutide Compared With …
Olinciguat
Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers).
Investigational
Matched Iupac: … (2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino ... ]-2-hydroxy-2-(trifluoromethyl)propanamide …
Matched Description: … Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole ... (IW-1701), in Healthy Volunteers). ... (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat …
Matched Description: … Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole ... (IW-1701), in Healthy Volunteers). ... (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat …
Pilaralisib
Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Glioblastoma, and Breast Cancer, among others.
Investigational
Matched Iupac: … 2-amino-N-[3-({3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl}sulfamoyl)phenyl]-2-methylpropanamide …
Matched Description: … Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 ... Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Glioblastoma …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Description: … Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 ... Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Glioblastoma …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Galicaftor
Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis.).
Investigational
Matched Iupac: … difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-7-(difluoromethoxy)-3,4-dihydro-2H-1-benzopyran-2- …
Matched Description: … Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability ... and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability ... and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Gatralimab
Gatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial and Repeat Treatment).
Investigational
Matched Description: … Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial ... Gatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml …
Dihydromorphine
A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Experimental
Illicit
Matched Description: … A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem] …
Ilaprazole
Ilaprazole has been investigated in Helicobacter Infections.
Investigational
Matched Iupac: … 2-[(4-methoxy-3-methylpyridin-2-yl)methanesulfinyl]-5-(1H-pyrrol-1-yl)-1H-1,3-benzodiazole …
Matched Description: … Ilaprazole has been investigated in Helicobacter Infections. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Ilaprazole has been investigated in Helicobacter Infections. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tivantinib
Tivantinib has been investigated in Solid Tumors.
Investigational
Matched Iupac: … (3R,4R)-3-{1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4,6,8(12)-tetraen-3-yl}-4-(1H-indol-3-yl)pyrrolidine …
Matched Description: … Tivantinib has been investigated in Solid Tumors. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Proto-Oncogene Proteins c-met, antagonists & inhibitors …
Matched Description: … Tivantinib has been investigated in Solid Tumors. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Proto-Oncogene Proteins c-met, antagonists & inhibitors …
Iguratimod
Iguratimod is under investigation in Rheumatoid Arthritis.
Investigational
Matched Iupac: … N-(7-methanesulfonamido-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide …
Matched Description: … Iguratimod is under investigation in Rheumatoid Arthritis. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Iguratimod is under investigation in Rheumatoid Arthritis. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bucindolol
Bucindolol has been investigated in Heart Failure.
Investigational
Matched Iupac: … 2-(2-hydroxy-3-{[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino}propoxy)benzonitrile …
Matched Description: … Bucindolol has been investigated in Heart Failure. …
Matched Description: … Bucindolol has been investigated in Heart Failure. …
G4544
G4544 is an oral gallium compound that enables oral absorption of the active ingredient contained in Ganite™ (gallium nitrate injection). It targets bone tissue and is actively incorporated into bone mineral at sites where bone is metabolically active.
Investigational
Matched Description: … G4544 is an oral gallium compound that enables oral absorption of the active ingredient contained in …
Displaying drugs 14826 - 14850 of 15697 in total