Displaying drugs 14851 - 14875 of 15697 in total
Puromycin
Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.
Experimental
Matched Iupac: … (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3 ... -yl]-3-(4-methoxyphenyl)propanamide …
Matched Description: … It is utilized as a selective agent in laboratory cell cultures. ... Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … It is utilized as a selective agent in laboratory cell cultures. ... Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Volrustomig
Volrustomig is under investigation in clinical trial NCT06097728 (MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma).
Investigational
Matched Description: … Volrustomig is under investigation in clinical trial NCT06097728 (MEDI5752 in Combination With Carboplatin ... Plus Pemetrexed in Unresectable Pleural Mesothelioma). …
PF-05241328
PF-05241328 is under investigation in clinical trial NCT01165736 (To Calculate the Pharmacokinetics (Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound Which Will Not Have Any Pharmacological Activity).
Investigational
Matched Iupac: … 1-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methanesulfonyl-3-methyl-1H-indazole-5-carboxamide …
Matched Description: … Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound ... PF-05241328 is under investigation in clinical trial NCT01165736 (To Calculate the Pharmacokinetics ( …
Matched Description: … Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound ... PF-05241328 is under investigation in clinical trial NCT01165736 (To Calculate the Pharmacokinetics ( …
Telatinib
Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine/ Oxaliplatin in 1st Line Gastric or GEJ Cancer).
Investigational
Matched Iupac: … 4-[({4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methylpyridine-2-carboxamide …
Matched Description: … Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine ... / Oxaliplatin in 1st Line Gastric or GEJ Cancer). …
Matched Description: … Telatinib is under investigation in clinical trial NCT03817411 (Telatinib in Combination With Capecitabine ... / Oxaliplatin in 1st Line Gastric or GEJ Cancer). …
Lactoferrin
Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
Investigational
Matched Description: … Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in ... Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis). …
Raclopride
Raclopride has been used in trials studying Parkinson Disease.
Investigational
Matched Iupac: … 3,5-dichloro-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-6-methoxybenzamide …
Matched Description: … Raclopride has been used in trials studying Parkinson Disease. …
Matched Description: … Raclopride has been used in trials studying Parkinson Disease. …
SJ-733
SJ-733 has been used in trials studying Malaria.
Investigational
Matched Iupac: … (3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline …
Matched Description: … SJ-733 has been used in trials studying Malaria. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … SJ-733 has been used in trials studying Malaria. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sulprostone
Sulprostone has been used in trials studying Abortion, Induced.
Investigational
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl]-N-methanesulfonylhept …
Matched Description: … Sulprostone has been used in trials studying Abortion, Induced. …
Matched Categories: … Prostaglandins E …
Matched Description: … Sulprostone has been used in trials studying Abortion, Induced. …
Matched Categories: … Prostaglandins E …
Ieramilimab
Ieramilimab is under investigation in clinical trial NCT02460224 (Safety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.).
Investigational
Matched Description: … Agent and in Combination With PDR001 in Patients With Advanced Malignancies.). ... Ieramilimab is under investigation in clinical trial NCT02460224 (Safety and Efficacy of LAG525 Single …
Rolicyclidine
Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.
Experimental
Illicit
Matched Description: … Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. ... the USA in the 1970s. ... similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in …
Pumosetrag
Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease.
Investigational
Matched Iupac: … N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-oxo-4H,7H-thieno[3,2-b]pyridine-6-carboxamide …
Matched Description: … Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease. …
Matched Description: … Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease. …
Imdusiran
Imdusiran is under investigation in clinical trial NCT06245291 (Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection).
Investigational
Matched Description: … Imdusiran is under investigation in clinical trial NCT06245291 (Study of Imdusiran (AB-729) in Combination ... With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection). …
siG12D LODER
siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).
Investigational
Matched Description: … siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in ... Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer). …
Levilimab
Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis).
Investigational
Matched Description: … -089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis). ... Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD …
Phosphonotyrosine
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid …
Matched Description: … Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly ... in cell growth control and carcinogenesis. ... An amino acid that occurs in endogenous proteins. …
Matched Description: … Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly ... in cell growth control and carcinogenesis. ... An amino acid that occurs in endogenous proteins. …
Rocakinogene sifuplasmid
Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)).
Investigational
Matched Description: … Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma ... Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 …
Ty800
Ty800 is a vaccine designed to offer rapid, oral, single-dose protection against Salmonella typhi, the cause of typhoid fever. The Ty800 vaccine was developed using genetic techniques to delete specific genes known to be essential to the virulence of S. typhi. It is being developed by AVANT Immunotherapeutics, Inc.
Investigational
Matched Description: … Ty800 is a vaccine designed to offer rapid, oral, single-dose protection against Salmonella typhi< …
Danusertib
Danusertib has been used in trials studying the treatment of Leukemia.
Investigational
Matched Iupac: … N-{5-[(2R)-2-methoxy-2-phenylacetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl …
Matched Description: … Danusertib has been used in trials studying the treatment of Leukemia. …
Matched Description: … Danusertib has been used in trials studying the treatment of Leukemia. …
Selurampanel
Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal.
Investigational
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-5-yl)-2,4-dioxo-7-(propan-2-yl)-1,2,3,4-tetrahydroquinazolin-3-yl]methanesulfonamide …
Matched Description: … Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Velneperit
Velneperit has been used in trials studying the treatment of Obesity.
Investigational
Matched Iupac: … (1r,4r)-4-(2-methylpropane-2-sulfonamido)-N-[5-(trifluoromethyl)pyridin-2-yl]cyclohexane-1-carboxamide …
Matched Description: … Velneperit has been used in trials studying the treatment of Obesity. …
Matched Description: … Velneperit has been used in trials studying the treatment of Obesity. …
ZSTK-474
ZSTK474 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Iupac: … 1-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-2-(difluoromethyl)-1H-1,3-benzodiazole …
Matched Description: … ZSTK474 has been used in trials studying the treatment of Neoplasms. …
Matched Description: … ZSTK474 has been used in trials studying the treatment of Neoplasms. …
Gallopamil
Gallopamil has been used in trials studying the treatment of Asthma.
Investigational
Matched Iupac: … 5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)-2-(3,4,5-trimethoxyphenyl)pentanenitrile …
Matched Description: … Gallopamil has been used in trials studying the treatment of Asthma. …
Matched Description: … Gallopamil has been used in trials studying the treatment of Asthma. …
DONU
Donu has been used in trials studying the treatment of Psychosis.
Investigational
Matched Iupac: … 3-(2-chloroethyl)-3-nitroso-1-[(1r,2R,6S)-2,6-dihydroxycyclohexyl]urea …
Matched Description: … Donu has been used in trials studying the treatment of Psychosis. …
Matched Description: … Donu has been used in trials studying the treatment of Psychosis. …
Dirocaftor
Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis).
Investigational
Matched Iupac: … N-[5-hydroxy-2,4-bis(trimethylsilyl)phenyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide …
Matched Description: … Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis). ... Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, …
Matched Description: … Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis). ... Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, …
Roquinimex
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Iupac: … 4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide …
Matched Description: … Roquinimex is a derivative of quinoline that presents immunostimulant properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Roquinimex is a derivative of quinoline that presents immunostimulant properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 14851 - 14875 of 15697 in total