Displaying drugs 126 - 150 of 389 in total
Benzethonium
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Bismuth subsalicylate
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation …
Miconazole
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Rapacuronium
Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.
Approved
Withdrawn
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Calcium Phosphate
Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Tiotropium
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093]
Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Mivacurium
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Approved
Pinaverium
Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Opicapone
Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine.[A36938, A203048] Many patients with Parkinson’s disease treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) experience motor complications over time, which calls for the management...
Approved
Investigational
Tramadol
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Metoclopramide
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Pafolacianine
Pafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum within a range of 760 nm to 785 nm, with a peak absorption of 776 nm. It emits fluorescence within a range of 790 nm to 815 nm with a...
Approved
Investigational
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Lenacapavir
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Barium
Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease.
Investigational
Matched Name: … Barium …
Matched Iupac: … barium …
Matched Description: … Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease. …
Matched Iupac: … barium …
Matched Description: … Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease. …
Gallium cation
Experimental
Matched Synonyms: … Gallium(3+) cation ... Gallium(III) cation …
Matched Name: … Gallium cation …
Matched Name: … Gallium cation …
Cobaltous cation
Experimental
Matched Synonyms: … Cobalt(II) cation ... Cobalt cation (Co2+) …
Matched Name: … Cobaltous cation …
Matched Name: … Cobaltous cation …
Nickel cation
Experimental
Matched Synonyms: … Nickel cation (Ni2+) ... Nickel(II) cation …
Matched Name: … Nickel cation …
Matched Name: … Nickel cation …
Chromic cation
Experimental
Matched Synonyms: … Chromium cation (3+) ... Chromium cation (Cr3+) ... Chromium(III) cation …
Matched Name: … Chromic cation …
Matched Name: … Chromic cation …
Bismuth cation
Experimental
Matched Synonyms: … bismuth(III) cation …
Matched Name: … Bismuth cation …
Matched Name: … Bismuth cation …
Lanthanum III cation
Experimental
Matched Synonyms: … Lanthanum cation (3+) ... Lanthanum cation (La3+) ... lanthanum(III) cation …
Matched Name: … Lanthanum III cation …
Matched Name: … Lanthanum III cation …
Gallium cation Ga-67
Experimental
Matched Synonyms: … Gallium (67Ga)cation ... Gallium cation Ga 67 ... Gallium Ga-67 cation …
Matched Name: … Gallium cation Ga-67 …
Matched Name: … Gallium cation Ga-67 …
Indium cation In-111
Experimental
Matched Synonyms: … Indium-111 cation ... Indium (111In) cation ... Indium cation In 111 …
Matched Name: … Indium cation In-111 …
Matched Name: … Indium cation In-111 …
Displaying drugs 126 - 150 of 389 in total