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Displaying drugs 126 - 150 of 11875 in total
Rilonacept
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Description: … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …
Nilotinib
Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Description: … benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec), another ... A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic …
Topiramate
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … In 2004, topiramate was approved for the prevention of migraine in adults. ... [A175249] It was initially approved by the FDA in 1996. ... with [phentermine] for chronic weight management therapy in adults. …
Matched Products: … Topamax 15 mg Granulat in Kapseln ... Topamax 25 mg Granulat in Kapseln ... Topamax 50 mg Granulat in Kapseln …
Matched Products: … Topamax 15 mg Granulat in Kapseln ... Topamax 25 mg Granulat in Kapseln ... Topamax 50 mg Granulat in Kapseln …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Products: … Alprazolam C-IV …
Tetracycline
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in …
Matched Products: … Tetra-C 74% w/w Water Soluble Powder …
Matched Products: … Tetra-C 74% w/w Water Soluble Powder …
Human interferon beta
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … [L12078] Interferon-beta has been used in the past in clinical studies with other coronaviruses due to ... (MS), and was initially approved by the FDA in 1992. ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Maralixibat
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Description: … [A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients ... [L38834] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... maralixibat be granted marketing authorization for the treatment of cholestatic pruritus in patients …
Motixafortide
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … of C-X-C Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow ... [A261476]
Motixafortide was approved by the FDA in September 2023, in combination with filgrastim ... , for use in stem cell mobilization prior to autologous stem cell transplant in patients with multiple …
Viltolarsen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Description: … Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they ... on further verification in confirmatory trials. ... [A218186, L15526] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … [A177553] In particular, increased dopamine in key brain areas is associated with the reinforcing and ... Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit ... [L6037] CADDRA recommends the use of methylphenidate due to long term studies, of over twenty years in …
Matched Products: … Ntp-methylphenidate ER-C ... Teva-methylphenidate ER-C …
Matched Products: … Ntp-methylphenidate ER-C ... Teva-methylphenidate ER-C …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal ... [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil ... samples from Mount Ararat in Turkey. …
Matched Products: … Daptomycin in Sodium Chloride …
Matched Products: … Daptomycin in Sodium Chloride …
Rosuvastatin
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … a sequence of metabolic reactions involved in the production of several compounds involved in lipid ... clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold ... this class becoming one of the most widely prescribed medications in North America. …
Matched Categories: … Drugs Used in Diabetes …
Matched Categories: … Drugs Used in Diabetes …
Fentanyl
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.
Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... [L6751]
Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] ... Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia …
Matched Products: … Actiq 200 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle ... Actiq 400 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle ... Actiq 600 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle …
Matched Products: … Actiq 200 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle ... Actiq 400 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle ... Actiq 600 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle …
Colloidal oatmeal
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … It is available in topical products as a skin soothing agent. ... Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities …
Matched Mixtures name: … Infinite Aloe All-IN-one Skin Care …
Matched Products: … 3-In-1 Relief CVS …
Matched Mixtures name: … Infinite Aloe All-IN-one Skin Care …
Matched Products: … 3-In-1 Relief CVS …
Citrus bioflavonoids
Approved
Experimental
Matched Mixtures name: … NAT-C ... KORDEL`S C TIME ACID FREE C 1000MG TABLET ... Special C …
Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … noxius*, *C. l. limpidus*, *C. l. tecomanus*, and *C. s. suffusus*. ... immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of *C. ... It was approved by FDA in 2011 and is marketed under the name Anascorp [L2196]. …
Miglustat
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Description: … Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... patients in the European Union, Brazil, and South Korea. ... Miglustat was first developed as an anti-HIV agent in the 1990s. …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Influenza A virus A/Texas/50/2012 X-223A (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … [A19626]
In a computational target-based drug repurposing investigation published in April 2020, elbasvir ... an infectious liver disease caused by infection with hepatitis C virus (HCV). ... a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …
Flutamide
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Matched Description: … An antiandrogen with about the same potency as cyproterone in rodent and canine species. …
Morphine
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … Morphine was granted FDA approval in 1941.[L12114] ... Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. …
Matched Products: … Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 100 mg - orale Lösung in Einzeldosisbehältern …
Matched Products: … Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 100 mg - orale Lösung in Einzeldosisbehältern …
Corynebacterium diphtheriae
Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … *Corynebacterium diphtheriae* toxin is extracted from the pathogenic actinobacterium *C. diphtheriae* ... The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants …
Matched Mixtures name: … Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze ... Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze ... Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze …
Displaying drugs 126 - 150 of 11875 in total