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Displaying drugs 1501 - 1525 of 1920 in total

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … REVOLADE FILM-COATED TABLET 25MG ... REVOLADE FILM-COATED TABLET 50MG ... REVOLADE 12.5 MG FİLM TABLET, 14 ADET …

Gemifloxacin

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Description: … broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and ... Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase …
Matched Products: … Factive film-coated tablet 320 mg ... ONFACT 320 MG FİLM TABLET, 5 ADET ... ONFACT 320 MG FİLM TABLET, 7 ADET …

Trametinib

Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and ... [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission ... currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors ... Mitogen-activated protein kinase (MEK) inhibitors …
Matched Products: … MEKINIST FILM-COATED TABLETS 2MG ... Meqsel 2mg Film-Coated Tablet ... MEKINIST FILM-COATED TABLETS 0.5MG …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Synonyms: … (S)-Pregn-4-en-3,20-dione ... Pregn-4-ene-3,20-dione …
Matched Description: … Please see [Medroxyprogesterone acetate], [Megestrol acetate], [Dydrogesterone] and [Hydroxyprogesterone ... , embryo implantation, and the successful establishment of pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Gesterol In Oil-liq Im 50mg/ml …

Tenofovir disoproxil

Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … LAMIHOPE-T (LAMIVUDINE 300MG AND TENOFOVIR DISOPROXIL FUMARATE 300MG FILM-COATED TABLETS) ... FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated ... TRUVADA 200 MG/245 MG FILM TABLET, 30 ADET …
Matched Salts name: … Tenofovir disoproxil phosphate …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and efavirenz ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TENVIR FILM-COATED TABLET ... VIRSOEM 245 MG FILM TABLET,30 ADET ... VIRSOEM 245 MG FILM TABLET, 90 ADET …

Vortioxetine

Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Matched Description: … an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. ... It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action ... serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and …
Matched Products: … Brintellix 5mg film-coated tablets ... Brintellix 15mg Film-coated Tablets ... Brintellix 20mg Film-coated Tablets …

Tofacitinib

Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … Known adverse effects include nausea and headache as well as more serious immunologic and hematological ... kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and ... tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … Xeljanz Film-Coated Tablets 5mg ... Tozib 5mg Film Coated Tablets ... JANTY 5 MG FİLM KAPLI TABLET, 56 ADET …

Spiramycin

Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium. Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in...
Approved
Matched Description: … Toxoplasma gondii and Cryptosporidium. ... a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and ... Resistant organisms include Enterobacteria, pseudomonads, and moulds. …
Matched Mixtures name: … METİRASİN 1,5 MIU/250 MG FILM TABLET, 10 ADET ... METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET …
Matched Categories: … spiramycin and metronidazole ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … FİLM KAPLI TABLET , 10 ADET ... FİLM KAPLI TABLET , 14 ADET ... SPRAMAX 1,5 MIU FİLM KAPLI TABLET, 10 ADET …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and ... JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Matched Products: … UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET ... OLUMIANT FILM-COATED TABLET 2MG ... OLUMIANT FILM-COATED TABLET 4MG …

Pirfenidone

Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate...
Approved
Investigational
Matched Description: … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that ... fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ESBRIET FILM COATED TABLET 267MG ... ESBRIET FILM COATED TABLET 801MG ... ESBRIET (FILM-COATED TABLETS 267 MG) …

Colesevelam

Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. …
Matched Products: … ZENUM 625 MG FILM TABLET, 180 ADET ... SARTOL 625 MG FİLM TABLET, 60 TABLET ... KOVEL 625 MG FİLM KAPLI TABLET, 30 ADET …

Efungumab

Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins …

Anti-CD5 CAR T-cell therapy

Investigational
Matched Synonyms: … chimeric antigen receptor (CAR) directed against the target protein CD5 …

Timolumab

Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Description: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis ... Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6 ... ) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … VERZENIO FILM-COATED TABLET 50MG ... VERZENIO FILM-COATED TABLET 100MG ... YULAREB 50 MG FİLM KAPLI TABLET, 28 ADET …

Brexpiprazole

Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Description: … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called ... It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. ... It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors. …
Matched Categories: … Sulfur Compounds …
Matched Products: … Rexulti 1mg film-coated tablets ... Rexulti 4mg film-coated tablets ... Rexulti 3mg film-coated tablets …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and ... Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and …
Matched Mixtures name: … ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 23 ADET 180 MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … ALUNBRIG FILM-COATED TABLET 30mg ... ALUNBRIG FILM-COATED TABLET 90mg ... ALUNBRIG FILM-COATED TABLET 180mg …

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … ARAMID 10 MG FILM TABLET ,FILM TABLET, 30 ADET ... ARAMID 20 MG FILM TABLET ,FILM TABLET, 30 ADET ... ARAMID 100 MG FİLM TABLET, 3 ADET …

Vericiguat

Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Iupac: … N-(4,6-diamino-2-{5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)carbamate …
Matched Description: … soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and ... messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and ... thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC activity …
Matched Products: … VERQUVO FILM-COATED TABLET 2.5MG ... VERQUVO FILM-COATED TABLET 10MG ... VERQUVO FILM-COATED TABLET 5MG …

Olmesartan

Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... increased excretion of sodium. …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... olmesartan medoxomil and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil and amlodipine …
Matched Products: … OMETAN 5 MG FILM TABLET,FILM TABLET, 28 ADET ... OMETAN 5 MG FILM TABLET,FILM TABLET, 84 ADET ... OMETAN 10 MG FILM TABLET,FILM TABLET, 28 ADET …

Dacomitinib

Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … Vizimpro 30 mg Film-Coated Tablets ... Vizimpro 15 mg Film-Coated Tablets ... VIZIMPRO FILM-COATED TABLET 15MG …

Ambrisentan

Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. ... ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … VOLIBRIS 10 MG FILM COATED TABLET ... VOLIBRIS FILM-COATED TABLET 5MG ... VOLIBRIS FILM-COATED TABLET 10 MG …

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG ... APROVASC FILM COATED TABLET 150MG/5MG …

Yellow fever vaccine

Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure...
Approved
Investigational
Matched Synonyms: … Flavivirus yellow fever virus 17D-204 whole …
Matched Description: … for laboratory personnel who handle virulent yellow fever virus or concentrated preparations of the ... measure to protect against Yellow Fever, with protective immunity developing within 10 days after vaccination ... of yellow fever in pediatric patients 9 months of age and older. …

BR-007

Investigational
Matched Synonyms: … -4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethoxy)carbonyl)amino)butane-1,1-diyl)bis(hydrogen phosphonate …
Matched Salts name: … BR-007 sodium …
Displaying drugs 1501 - 1525 of 1920 in total