Displaying drugs 1551 - 1575 of 1780 in total
Ifinatamab deruxtecan
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Dapiclermin
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Porgaviximab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY ... with human-mus musculus monoclonal c2g4 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide …
Sevirumab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human …
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... insulin, and in the long term, damage to pancreatic islet cells. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... insulin, and in the long term, damage to pancreatic islet cells. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Immucin
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
Pemtumomab
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Description: … Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … PEGylated recombinant anti-Pseudomonas aeruginosa PcrV Fab' antibody ... KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS ... ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN, PEGYLATED HUMANIZED MONOCLONAL ANTIBODY …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … to both intra- and extravascular hemolysis. ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … to both intra- and extravascular hemolysis. ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Homeostasis ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Parathyroid Hormones and Analogues …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Homeostasis ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Parathyroid Hormones and Analogues …
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... that regulates the over-production of complement at the cell surface, which occurs in inflammation. …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... that regulates the over-production of complement at the cell surface, which occurs in inflammation. …
Eptacog alfa pegol (activated)
Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With Inhibitors.
Investigational
Matched Synonyms: … Activated Recombinant Human Factor VII, Long Acting …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … impairment, intellectual disability, and respiratory dysfunction. ... to progressive neuromuscular and skeletal deterioration, such as skeletal abnormalities, motor function ... The resulting accumulation of sugars in the body leads to an array of clinical manifestations leading …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … impairment, intellectual disability, and respiratory dysfunction. ... to progressive neuromuscular and skeletal deterioration, such as skeletal abnormalities, motor function ... The resulting accumulation of sugars in the body leads to an array of clinical manifestations leading …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Pegilodecakin
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …
Matched Description: … With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Larcaviximab
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c4g7 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c4g7 heavy chain), disulfide …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these...
Investigational
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … modify artificial antigen presenting cells (aAPC), and activate T-cells. ... structural proteins and a polyprotein protease. ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and …
Matched Description: … modify artificial antigen presenting cells (aAPC), and activate T-cells. ... structural proteins and a polyprotein protease. ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and …
MK-2225
Investigational
Matched Synonyms: … transforming growth factor beta receptor type II linked to a human IgG1 Fc domain ... Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human …
Humate-P
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Synonyms: … Human albumin I-125 ... Human serum albumin I-125 ... Iodinated (125I) human serum albumin …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Bambusa vulgaris top
Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Bambusa Vulgaris Leaf/stem Extract …
Letrozole
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETRO CELL 2.5 MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETRO CELL 2.5 MG …
Lanimostim
Investigational
Matched Synonyms: … 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced) …
Displaying drugs 1551 - 1575 of 1780 in total