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Displaying drugs 151 - 175 of 10402 in total

Flunarizine

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Description: … of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an …
Matched Categories: … Antiarrhythmic agents ... Histamine Agents ... Agents causing hyperkalemia ... Cardiovascular Agents ... Vasodilating Agents …

Brexucabtagene autoleucel

Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. Despite the introduction of Bruton's tyrosine kinase (BTK) inhibitors such as ibrutinib and acalabrutinib, the prognosis for MCL patients remains poor and those that relapse...
Approved
Matched Description: … as either an aggressive nodal or an indolent leukemic non-nodal variant. ... Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified …
Matched Categories: … Antineoplastic Agents ... Antineoplastic Agents, Immunological ... Antineoplastic and Immunomodulating Agents …

Rotigotine

Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Description: … It was approved by the European Medicines Agency in 2006 and by the FDA in 2007. …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Serotonin Agents ... Hypotensive Agents ... Agents that produce hypertension …

Pentostatin

A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Approved
Investigational
Matched Description: … It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. …
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Cardiotoxic antineoplastic agents ... Antineoplastic and Immunomodulating Agents …

Ansuvimab

Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … Ansuvimab is just the second FDA-approved treatment for EVD.[L29560] ... antibodies (mAbs) against the GP1,2 surface glycoprotein, as evidenced by the previously approved ... INMAZEB™ (REGN-EB3, a cocktail of [atoltivimab], [odesivimab], and [maftivimab]), the now approved ansuvimab …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents …

Desonide

A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Inflammatory Agents ... Immunosuppressive Agents …

Acetylcarnitine

Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India. Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans. In human plasma and tissues,...
Approved
Investigational
Matched Description: … , and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India ... Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel ... human plasma and tissues, acetylcarnitine is the most predominant acylated ester of carnitine, which is an …
Matched Categories: … Nootropic Agents ... Central Nervous System Agents ... Psychostimulants, Agents Used for ADHD and Nootropics …

Peanut oil

Peanut oil is derived from Arachis hypogaea which can be found in South America, Mexico, and Centro America. The kernels are consumed roasted but a large percentage is used for the production of vegetable oil. The peanut oil represents about 45-52% of the kernel content and it is mainly formed...
Approved
Matched Description: … [A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in ... [L2242] Under Health Canada, it is approved as an active ingredient in over-the-counter combination products …

Trazodone

Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Triazolopyridine ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Anti-Anxiety Agents …

Cetalkonium

Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Description: … Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows ... [L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] ... [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and …
Matched Categories: … Anti-Infective Agents ... Surface-Active Agents ... Anti-Infective Agents, Local …

Procarbazine

An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Description: … An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone …
Matched Categories: … Antidepressive Agents ... Serotonin Agents ... Antineoplastic Agents ... Agents Causing Muscle Toxicity ... Myelosuppressive Agents …

Mogamulizumab

Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically...
Approved
Investigational
Matched Description: … [L4168] It was approved for the same indications in Canada in June 2022. ... Food and Drug Administration (FDA) approved mogamulizumab injection (also known as _Poteligeo_) for intravenous …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Deflazacort

Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label] Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Description: … It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA. ... Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular ... [L6694,FDA label] Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of …
Matched Categories: … Anti-Inflammatory Agents ... Immunosuppressive Agents ... Hyperglycemia-Associated Agents …

Benzatropine

Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Description: … [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500] ... with the presence of a chlorine substituent in the para position in one of the phenyl rings produces an …
Matched Categories: … Dopamine Agents ... Cholinergic Agents ... Anti-Dyskinesia Agents ... Anticholinergic Agents ... Agents producing tachycardia …

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Description: … A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably …

Thiethylperazine

A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Approved
Withdrawn
Matched Description: … useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents …
Matched Categories: … Autonomic Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents ... Gastrointestinal Agents …

Bictegravir

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Matched Categories: … Antiviral Agents …

Pomalidomide

Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Approved
Matched Description: … FDA approved on February 8, 2013. ... Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. …
Matched Categories: … Antineoplastic Agents ... Angiogenesis Modulating Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Vandetanib

Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Approved
Matched Description: … Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation ... On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic …
Matched Categories: … Antineoplastic Agents ... QTc Prolonging Agents ... Photosensitizing Agents ... Highest Risk QTc-Prolonging Agents ... Antineoplastic and Immunomodulating Agents …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Categories: … GABA Agents ... Anticholinergic Agents ... Hypotensive Agents ... Neurotransmitter Agents ... Central Nervous System Agents …

Carboxin

A systemic agricultural fungicide and seed treatment agent.
Approved
Experimental

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …

Benzyl alcohol

Approved
Matched Categories: … Dental Agents ... Sensory System Agents ... Central Nervous System Agents ... Peripheral Nervous System Agents …

Haloperidol

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … medications such as haloperidol are though to improve psychotic symptoms and states that are caused by an …
Matched Categories: … Autonomic Agents ... Antipsychotic Agents ... Anti-Dyskinesia Agents ... Dopamine Agents ... Neurotoxic agents …
Matched Products: … Truemed Group LLC …

Lithium citrate

Approved
Matched Categories: … Antidepressive Agents ... Antimanic Agents ... Neurotoxic agents ... Serotonin Agents ... Nephrotoxic agents …
Displaying drugs 151 - 175 of 10402 in total