Displaying drugs 1726 - 1750 of 2924 in total
Cinalukast
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Experimental
Matched Synonyms: … 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Description: … inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Description: … inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and …
Phosphorylcolamine
Experimental
Matched Synonyms: … Colamine phosphoric acid …
Matched Iupac: … (2-aminoethoxy)phosphonic acid …
Matched Iupac: … (2-aminoethoxy)phosphonic acid …
2-Iminobiotin
Experimental
Investigational
Matched Synonyms: … Hexahydro-2-imino-1h-thieno(3,4-d)imidazole-4-pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid
Experimental
Matched Synonyms: … 3-(4-diethylamino-2-hydroxy-phenyl)-2-methyl-propionic acid …
Matched Name: … alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid …
Matched Iupac: … (2E)-3-[4-(diethylamino)-2-hydroxyphenyl]-2-methylprop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid …
Matched Iupac: … (2E)-3-[4-(diethylamino)-2-hydroxyphenyl]-2-methylprop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Terameprocol
Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Synonyms: … meso-Tetra-O-methylnordihydroguaiaretic acid …
Matched Description: … Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors. …
Matched Description: … Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors. …
ARM-210
Investigational
Matched Synonyms: … 4-((7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5h)-yl)methyl)benzoic acid ... Benzoic acid, 4-((2,3-dihydro-7-methoxy-1,4-benzothiazepin-4(5h)-yl)methyl)- …
Matched Iupac: … 4-[(7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepin-4-yl)methyl]benzoic acid …
Matched Iupac: … 4-[(7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepin-4-yl)methyl]benzoic acid …
PF-00356231
Experimental
Matched Synonyms: … (3R)-3-Phenyl-3-[({4-[4-(4-pyridinyl)phenyl]-2-thienyl}carbonyl)amino]propanoic acid ... 3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid …
Matched Iupac: … (3R)-3-phenyl-3-({4-[4-(pyridin-4-yl)phenyl]thiophen-2-yl}formamido)propanoic acid …
Matched Iupac: … (3R)-3-phenyl-3-({4-[4-(pyridin-4-yl)phenyl]thiophen-2-yl}formamido)propanoic acid …
Adenosine phosphate
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Synonyms: … 5'-Adenylic acid ... Adenylic acid ... Adenosine-5'-monophosphoric acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Description: … by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and ... Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Description: … by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and ... Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Technetium Tc-99m medronate
Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way...
Approved
Matched Synonyms: … Technetium (99mTc) medronic acid ... Technetium 99mTc medronic acid ... Technetium Tc 99m medronic acid …
Matched Description: … crystals within bone, and in this way localizes the drug to bone for delineation of areas of altered ... Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. ... It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. …
Matched Categories: … Indicators and Reagents ... technetium (99mTc) medronic acid …
Matched Description: … crystals within bone, and in this way localizes the drug to bone for delineation of areas of altered ... Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. ... It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. …
Matched Categories: … Indicators and Reagents ... technetium (99mTc) medronic acid …
Ginisortamab
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Tenofovir amibufenamide
Investigational
Matched Synonyms: … Alanine, n-((s)-(((1r)-2-(6-amino-9h-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-2-methyl-, …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROKIN-X. ... PROKIN-X® ... PROKIN-X. 120 …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROKIN-X. ... PROKIN-X® ... PROKIN-X. 120 …
Froniglutide
Glymera is under investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM).
Investigational
Matched Synonyms: … L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryp …
Matched Description: … investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and ... Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of …
Matched Description: … investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and ... Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of …
Terlipressin
Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Salts name: … Terlipressin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Vasopressin and Analogues …
Matched Products: … TERLIPRESSINA ACETATO EVER PHARMA …
Matched Salts name: … Terlipressin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Vasopressin and Analogues …
Matched Products: … TERLIPRESSINA ACETATO EVER PHARMA …
(S)-propane-1,2-diol
(S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Experimental
Matched Synonyms: … (S)-propane-1,2-diol …
Matched Name: … (S)-propane-1,2-diol …
Matched Iupac: … (2S)-propane-1,2-diol …
Matched Description: … (S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical …
Matched Name: … (S)-propane-1,2-diol …
Matched Iupac: … (2S)-propane-1,2-diol …
Matched Description: … (S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical …
DIETHYL PROPANE-1,3-DIYLBISCARBAMATE
Experimental
Matched Name: … DIETHYL PROPANE-1,3-DIYLBISCARBAMATE …
Piperaquine
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 ... Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artenimol and piperaquine ... arterolane and piperaquine ... artemisinin and piperaquine …
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 ... Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artenimol and piperaquine ... arterolane and piperaquine ... artemisinin and piperaquine …
Abequolixron
Investigational
Matched Synonyms: … ((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2- diphenylethyl)amino)butoxy)phenyl)acetic acid ... -((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid ... -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Zanamivir
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid ... 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Carboxylic Acids ... Sialic Acids ... Hydroxy Acids …
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Carboxylic Acids ... Sialic Acids ... Hydroxy Acids …
(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
Experimental
Matched Synonyms: … (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
S-Ethylisothiourea
S-Ethylisothiourea is a nitric oxide synthase inhibitor.
Experimental
Matched Synonyms: … CARBAMIMIDOTHIOIC ACID, ETHYL ESTER …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Cilomilast
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
Matched Synonyms: … cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and ... It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. ... proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and ... It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. ... proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Lithium citrate
Approved
Matched Synonyms: … Citric acid, trilithium salt …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Displaying drugs 1726 - 1750 of 2924 in total