Displaying drugs 1801 - 1825 of 2884 in total
4-Methyl-Pyrroline-5-Carboxylic Acid
Experimental
Matched Name: … 4-Methyl-Pyrroline-5-Carboxylic Acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid
Experimental
Matched Name: … 3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid …
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid …
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid …
2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID
Experimental
Matched Name: … 2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID …
Matched Iupac: … 2',6'-difluoro-[1,1'-biphenyl]-4-carboxylic acid …
Matched Iupac: … 2',6'-difluoro-[1,1'-biphenyl]-4-carboxylic acid …
5-(2-METHOXYPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-METHOXYPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-methoxyphenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-methoxyphenyl)furan-2-carboxylic acid …
5-(2-NITROPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-NITROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-nitrophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-nitrophenyl)furan-2-carboxylic acid …
(2R)-2-ETHYL-1-HEXANESULFONIC ACID
Experimental
Matched Name: … (2R)-2-ETHYL-1-HEXANESULFONIC ACID …
Matched Iupac: … {[(2R)-2-ethylhexyl]oxy}sulfonic acid …
Matched Iupac: … {[(2R)-2-ethylhexyl]oxy}sulfonic acid …
5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2,5-dichlorophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2,5-dichlorophenyl)furan-2-carboxylic acid …
5-phenyl-2-keto-valeric acid
Experimental
Matched Name: … 5-phenyl-2-keto-valeric acid …
Matched Iupac: … 2-oxo-5-phenylpentanoic acid …
Matched Iupac: … 2-oxo-5-phenylpentanoic acid …
4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Experimental
Matched Name: … 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …
(S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID
Experimental
Matched Name: … (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID …
Matched Iupac: … (2S)-5-phenyl-2-(sulfanylmethyl)pentanoic acid …
Matched Iupac: … (2S)-5-phenyl-2-(sulfanylmethyl)pentanoic acid …
PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
Experimental
Matched Name: … PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE …
4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID
Experimental
Matched Name: … 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID …
Matched Iupac: … 4-({4-[(1E)-2-phenylethenyl]phenyl}carbamoyl)butanoic acid …
Matched Iupac: … 4-({4-[(1E)-2-phenylethenyl]phenyl}carbamoyl)butanoic acid …
N-Methylmesoporphyrin containing copper
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Metrifonate
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Iupac: … dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate …
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate …
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Lesinurad
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Salts name: … Eflornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Diamino …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Salts name: … Eflornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Diamino …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Candoxatril
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Description: … It has few side effects and is reported to be safe and effective in aged patients and in patients with ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Categories: … Thiazines …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Description: … It has few side effects and is reported to be safe and effective in aged patients and in patients with ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Categories: … Thiazines …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
3,6-dihydroxy-xanthene-9-propionic acid
Experimental
Matched Name: … 3,6-dihydroxy-xanthene-9-propionic acid …
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid …
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid …
(5r)-5-Amino-6-Hydroxyhexylcarbamic Acid
Experimental
Matched Name: … (5r)-5-Amino-6-Hydroxyhexylcarbamic Acid …
Matched Iupac: … [(5S)-5-amino-6-hydroxyhexyl]carbamic acid …
Matched Iupac: … [(5S)-5-amino-6-hydroxyhexyl]carbamic acid …
Displaying drugs 1801 - 1825 of 2884 in total