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Displaying drugs 1801 - 1825 of 2640 in total
Experimental
Matched Name: … 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID
Matched Iupac: … 4-({4-[(1E)-2-phenylethenyl]phenyl}carbamoyl)butanoic acid
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Experimental
Matched Name: … 3,6-dihydroxy-xanthene-9-propionic acid
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid
Experimental
Matched Name: … 2(S)-Amino-6-Boronohexanoic Acid
Experimental
Matched Name: … (5r)-5-Amino-6-Hydroxyhexylcarbamic Acid
Matched Iupac: … [(5S)-5-amino-6-hydroxyhexyl]carbamic acid
Experimental
Matched Name: … 4-(Carboxyvin-2-Yl)Phenylboronic Acid
Matched Iupac: … (2E)-3-[4-(dihydroxyboranyl)phenyl]prop-2-enoic acid
Experimental
Matched Name: … 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
Matched Iupac: … 3-(1,3-benzothiazol-2-ylsulfanyl)propane-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids
Experimental
Matched Name: … 6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid
Matched Iupac: … (6S)-8-[(aminomethyl)sulfanyl]-6-[(2-hydroxyethyl)disulfanyl]octanoic acid
Experimental
Matched Name: … 7-(Carboxyamino)-8-Amino-Nonanoic Acid
Matched Iupac: … (7R,8S)-8-amino-7-(carboxyamino)nonanoic acid
Experimental
Matched Name: … 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
Matched Iupac: … (2R,3R,4S,5R,6S)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid
Experimental
Matched Name: … (10R)-10-formyl-5,8,10-trideazafolic acid
Matched Iupac: … ({4-[(1R)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic acid
Experimental
Matched Name: … Benzo[B]Thiophene-2-Boronic Acid
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid
Experimental
Matched Name: … (2R)-2-benzyl-3-nitropropanoic acid
Matched Iupac: … (2R)-2-benzyl-3-nitropropanoic acid
Experimental
Matched Name: … 3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID
Matched Iupac: … 3',5'-difluoro-[1,1'-biphenyl]-4-carboxylic acid
Experimental
Matched Name: … 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID
Matched Iupac: … 4-[(cyclohexylcarbamoyl)amino]butanoic acid
Experimental
Matched Name: … 6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID
Matched Iupac: … 6-[(cyclohexylcarbamoyl)amino]hexanoic acid
Experimental
Matched Name: … 7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID
Matched Iupac: … 7-[(cyclohexylcarbamoyl)amino]heptanoic acid
Experimental
Matched Name: … 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Displaying drugs 1801 - 1825 of 2640 in total