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Displaying drugs 1826 - 1850 of 2301 in total
Crenolanib
Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Investigational
Matched Iupac: … 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine …
1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
Experimental
1,8-Di-Hydroxy-4-Nitro-Anthraquinone
Experimental
Dimethylaminomicheliolide
Investigational
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Coronavirus-Like Particle COVID-19 Vaccine
The Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection. VLPs are thought to have multiple mechanisms involving the...
Investigational
Matched Description: … immunogenicity of this vaccine candidate with or without either Cpg 1018 or AS03 (NCT04450004) in adults aged 18 …
Magrolimab
Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
PKI-179
PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
Investigational
Matched Iupac: … 3-{4-[4-(morpholin-4-yl)-6-[(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]-1,3,5-triazin-2-yl]phenyl}-1 …
Cryptoxanthin
Experimental
Matched Iupac: … (1R)-3,5,5-trimethyl-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex …
Nonivamide
Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) .
Nonivamide is a flavoring ingredient. Nonivamide is an...
Investigational
Matched Description: … DB06774] and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8- …
Diphenyleneiodonium
An NADPH oxidase 2 (NOX2) inhibitor.
Investigational
Matched Iupac: … 8lambda3-iodatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-8-ylium …
5beta-dihydrotestosterone
Experimental
BC9KBY85WY
Investigational
PRI-724
PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).
Investigational
Matched Iupac: … (4-{[(6S,9S,9aS)-1-(benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-[(quinolin-8-yl)methyl]-octahydro-1H-pyrazino …
10-formyl-5,8,10-trideazafolic acid
Experimental
6,8-DIMERCAPTO-OCTANOIC ACID AMIDE
Experimental
AZD-7325
AZD7325 is a high affinity, selective modulator of the GABAA receptor system.
Investigational
Matched Iupac: … 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide …
Silmitasertib
Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).
Investigational
Matched Iupac: … 5-[(3-chlorophenyl)amino]benzo[c]2,6-naphthyridine-8-carboxylic acid …
Caryophyllene
Investigational
Matched Iupac: … (1R,4Z,9S)-4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene …
Basic Fibroblast Growth Factor
Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative...
Investigational
Matched Description: … Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative …
INHIBITOR Q8467 OF DUPONT MERCK
Experimental
Loxicodegol
Loxicodegol was developed by Nektar Therapeutics as an opioid analgesic with low abuse potential for the treatment of chronic pain . The lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class...
Investigational
Matched Iupac: … hexaoxanonadecan-19-yloxy)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18 …
Calystegine B2
Experimental
Matched Iupac: … (1R,2S,3R,4S,5R)-8-azabicyclo[3.2.1]octane-1,2,3,4-tetrol …
Displaying drugs 1826 - 1850 of 2301 in total