Displaying drugs 1826 - 1850 of 1870 in total
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Ceftiofur
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Matched Salts name: … Ceftiofur sodium …
Matched Salts name: … Ceftiofur sodium …
Refametinib
Investigational
Taurochenodeoxycholic acid
Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile...
Experimental
Matched Description: … It is also being investigated for its role in inflammation and cancer therapy. ... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely ... used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …
Drostanolone
Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy.
Illicit
Cibisatamab
Investigational
Matched Synonyms: … immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
DCLL-9718S
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AOC-1020
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
Matched Description: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
Matched Description: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …
Denufosol
Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial. A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in...
Investigational
Matched Description: … Denufosol has not gained FDA approval, and clinical trials with this drug have ceased since 2011. ... The drug was also evaluated in the treatment of retinal detachment and other diseases of the retina. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
CP-12
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …
Pyritinol
Pyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Reproterol
Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
Investigational
Matched Categories: … reproterol and sodium cromoglicate …
STRO-001
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
Clocapramine
Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been implicated in at least one strange death,...
Experimental
Matched Description: … to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and …
Demplatin pegraglumer
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Saccharin
Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.
Investigational
Matched Description: … Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia. …
Matched Salts name: … Saccharin sodium …
Matched Categories: … Diet, Food, and Nutrition …
Matched Salts name: … Saccharin sodium …
Matched Categories: … Diet, Food, and Nutrition …
Tefidsogene civaparvovec
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Orvacabtagene autoleucel
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
Prexasertib
Prexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Investigational
Matched Description: … , breast cancer, and Ovarian Cancer, among others. ... Prexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm …
Matched Salts name: … Prexasertib mesylate monohydrate …
Matched Salts name: … Prexasertib mesylate monohydrate …
Prothipendyl
Prothipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Salts name: … Prothipendyl hydrochloride monohydrate …
Matched Salts name: … Prothipendyl hydrochloride monohydrate …
Displaying drugs 1826 - 1850 of 1870 in total