Displaying drugs 1876 - 1900 of 2177 in total
Rosomidnar
Investigational
Matched Synonyms: … (3'-5')d(c-a-c-g-c-a-c-g-c-g-c-a-t-c-c-c-c-g-c-c-c-g-t-g) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Miglustat
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Synonyms: … NB-DNJ ... 1,5-(butylimino)-1,5-dideoxy, D-glucitol …
Matched Description: … patients in the European Union, Brazil, and South Korea. ... Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Salts name: … Miglustat hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Description: … patients in the European Union, Brazil, and South Korea. ... Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Salts name: … Miglustat hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Pinometostat
Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Synonyms: … -D-RIBOFURANOSYL)- …
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and …
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and …
Bersiporocin
Investigational
Matched Synonyms: … (2r,3s)-2-(3-(4,5-dichloro-1h-benzo(d)imidazol-1-yl)propyl)piperidin-3-ol …
Matched Salts name: … Bersiporocin hydrochloride …
Matched Salts name: … Bersiporocin hydrochloride …
Isosorbide dinitrate
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Approved
Investigational
Matched Synonyms: … D-Isosorbide dinitrate ... Dinitrato de isosorbida …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … DINITRATO DE ISOSORBIDE DE 40 MG ... DINITRATO DE ISOSORBIDE TABLETAS 10MG …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … DINITRATO DE ISOSORBIDE DE 40 MG ... DINITRATO DE ISOSORBIDE TABLETAS 10MG …
Ticagrelor
Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, .
Ticagrelor was...
Approved
Matched Synonyms: … ,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d) …
Matched Iupac: … )-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d] …
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … TICAGRELOR DOC ... TICAGRELOR DR. REDDY'S …
Matched Iupac: … )-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d] …
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … TICAGRELOR DOC ... TICAGRELOR DR. REDDY'S …
Adagrasib
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … -(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido(3,4-d) ... (7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl)methoxy)pyrido(3,4-d) …
Matched Iupac: … 2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4-d] …
Matched Description: … KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations ... for guanosine triphosphate (GTP) and guanosine diphosphate (GDP), as well as the lack of a clear binding ... Adagrasib targets KRASG12C, one of the most common KRAS mutations, at the cysteine 12 residue and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4-d] …
Matched Description: … KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations ... for guanosine triphosphate (GTP) and guanosine diphosphate (GDP), as well as the lack of a clear binding ... Adagrasib targets KRASG12C, one of the most common KRAS mutations, at the cysteine 12 residue and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
Experimental
Matched Name: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
Matched Iupac: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
Matched Iupac: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone
Experimental
Matched Name: … 2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone …
2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole …
2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole …
9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
20-Hydroxyecdysone
Investigational
Matched Synonyms: … 20-hydroxy-.alpha.-ecdysone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … INTERLEUKIN 15 RECEPTOR .ALPHA. ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(1H-indol-6-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(1H-indol-6-yl)phenyl]methyl}pyridine-2,3-diamine …
1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE
Experimental
Matched Name: … 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE …
Matched Iupac: … 1-(2-nitrobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine-6-carboxamide …
Matched Iupac: … 1-(2-nitrobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine-6-carboxamide …
Enzacamene
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Enzacamene D-L form ... 3-(p-Methylbenzylidene)-DL-camphor …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and …
Matched Mixtures name: … mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS ... Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and …
Matched Mixtures name: … mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS ... Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen …
1-Deoxy-1-methoxycarbamido-beta-D-gluco-2-heptulopyranosonamide
Experimental
Matched Name: … 1-Deoxy-1-methoxycarbamido-beta-D-gluco-2-heptulopyranosonamide …
2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside
Experimental
Matched Name: … 2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside …
1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE
Experimental
Matched Name: … 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE …
N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE
Experimental
Matched Name: … N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE …
Matched Iupac: … 2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}amino)acetic acid …
Matched Iupac: … 2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}amino)acetic acid …
Bamocaftor
Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Synonyms: … 6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Iupac: … -{2-[1-(trifluoromethyl)cyclopropyl]ethoxy}-1H-pyrazol-1-yl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Description: … Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and …
Matched Iupac: … -{2-[1-(trifluoromethyl)cyclopropyl]ethoxy}-1H-pyrazol-1-yl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Description: … Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and …
Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate
Experimental
Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …
Displaying drugs 1876 - 1900 of 2177 in total