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Displaying drugs 1876 - 1900 of 6223 in total
Purvalanol A
Experimental
Matched Synonyms: … 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine …
Matched Iupac: … (2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol …
Matched Iupac: … (2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol …
Ajoene
Investigational
Matched Synonyms: … 4,5,9-trithiadodeca-1,6,11-triene 9-oxide ... (E, Z)-4,5,9-trithiadodeca-1, 6, 11-triene 9-oxide (Ajoene) ... Disulfide, 2-propenyl 3-(2-propenylsulfinyl)-1-propenyl …
Tapencarium
Investigational
Matched Synonyms: … 5-[3,6-dibromo-9H-carbazol-9-yl]-N,N,N-trimethylpentan-1-aminium chloride …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE
Experimental
Matched Name: … ,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9- …
Seliciclib
R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex...
Investigational
Matched Synonyms: … 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Aminacrine
A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
Experimental
Matched Synonyms: … 9-acridinamine …
Matched Iupac: … acridin-9-amine …
Matched Salts cas: … 134-50-9 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … acridin-9-amine …
Matched Salts cas: … 134-50-9 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Dimethylthiambutene
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Experimental
Illicit
Matched Synonyms: … N,N,1-trimethyl-3,3-di-2-thienylallylamine ... N,N,1-trimethyl-3,3-di(2-thienyl)-2-propenylamine ... 3-dimethylamino-1,1-bis(2-thienyl)-1-butene …
Matched Iupac: … [4,4-bis(thiophen-2-yl)but-3-en-2-yl]dimethylamine …
Matched Description: … Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid …
Matched Iupac: … [4,4-bis(thiophen-2-yl)but-3-en-2-yl]dimethylamine …
Matched Description: … Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid …
DMP-777
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy …
Lucanthone
One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.
Investigational
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one ... 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Tirabrutinib
Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one …
Matched Iupac: … 6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one …
Matched Salts cas: … 1439901-97-9 …
Matched Iupac: … 6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one …
Matched Salts cas: … 1439901-97-9 …
Dimethylaminomicheliolide
Investigational
Matched Synonyms: … AZULENO(4,5-B)FURAN-2(3H)-ONE, 3-((DIMETHYLAMINO)METHYL)-3A,4,5,7,8,9,9A,9B-OCTAHYDRO-9-HYDROXY-6,9-DIMETHYL …
Matched Iupac: … (3R,3aS,9R,9aS,9bS)-3-[(dimethylamino)methyl]-9-hydroxy-6,9-dimethyl-2H,3H,3aH,4H,5H,7H,8H,9H,9aH,9bH-azuleno …
Matched Iupac: … (3R,3aS,9R,9aS,9bS)-3-[(dimethylamino)methyl]-9-hydroxy-6,9-dimethyl-2H,3H,3aH,4H,5H,7H,8H,9H,9aH,9bH-azuleno …
Ro 12-7310
Experimental
Matched Synonyms: … (2E,4E,6E,8E)-9-(4-Hydroxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid …
SD146
Experimental
Matched Synonyms: … 3,3'-{[(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-2-oxo-1,3-diazepane-1,3-diyl]bis(methylene)}bis[N-(1H-benzimidazol …
Matched Iupac: … N-(1H-1,3-benzodiazol-2-yl)-3-{[(4R,5S,6S,7R)-3-({3-[(1H-1,3-benzodiazol-2-yl)carbamoyl]phenyl}methyl …
Matched Iupac: … N-(1H-1,3-benzodiazol-2-yl)-3-{[(4R,5S,6S,7R)-3-({3-[(1H-1,3-benzodiazol-2-yl)carbamoyl]phenyl}methyl …
Gosogliptin
Gosogliptin has been used in trials studying the treatment of Renal Insufficiency, Chronic.
Investigational
Matched Synonyms: … 2-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidine …
Matched Iupac: … 2-{4-[(3S,5S)-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazin-1-yl}pyrimidine …
Matched Iupac: … 2-{4-[(3S,5S)-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazin-1-yl}pyrimidine …
VS-5584
VS-5584 has been used in trials studying the treatment of Lymphoma, Metastatic Cancer, and Non Hematologic Cancers.
Investigational
Matched Synonyms: … 2-pyrimidinamine, 5-(8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl)- ... 5-[8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6yl]-2-pyrimidinamine …
Matched Iupac: … 5-[8-methyl-2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine …
Matched Iupac: … 5-[8-methyl-2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine …
Dextromoramide
An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Experimental
Illicit
Matched Synonyms: … 4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine ... (+)-4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine ... (+)-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine …
Matched Iupac: … (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one …
Matched Iupac: … (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one …
APT-101
Investigational
Matched Synonyms: … (S)-3-(1-Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin …
Matched Iupac: … (3S)-3-({1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin …
Matched Iupac: … (3S)-3-({1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin …
TSHA-101
Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …
Ritivixibat
Investigational
Matched Synonyms: … 3-([3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-1Lambda6,2,5-benzothiadiazepin …
Matched Iupac: … 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
Matched Iupac: … 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
Etoposide toniribate
Investigational
Matched Synonyms: … -d-glucopyranosyl)oxy)-6-oxo-5,5a,6,8,8a,9-hexahydro-2h-furo(3',4':6,7)naphtho(2,3-d)(1,3)dioxol-5-yl ... -d-glucopyranosyl)oxy)-5,5a,6,8,8a,9-hexahydro-6-oxofuro(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-5-yl)-2,6 ... ((4rs)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl4-((5r,5ar,8ar,9s)-9-((4,6-o-((1r)-ethane-1,1-diyl)-.beta …
Matched Iupac: … 2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9) …
Matched Iupac: … 2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9) …
LH-708
Investigational
Matched Synonyms: … 1-propanone, 3,3'-dithiobis(2-amino-1-(4-methyl-1-piperazinyl)-, (2r,2'r)- …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-3-(4-methylpiperazin-1-yl)-3-oxopropyl]disulfanyl}-1-(4-methylpiperazin …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-3-(4-methylpiperazin-1-yl)-3-oxopropyl]disulfanyl}-1-(4-methylpiperazin …
Pimicotinib
Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).
Investigational
Matched Synonyms: … 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]- ... 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamide …
LGD-3303
An androgen receptor modulator.
Experimental
Matched Synonyms: … 9-Chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-F)quinolin-7(6H)-one …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE
Experimental
Matched Name: … 18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9- …
Fordadistrogene movaparvovec
Investigational
Matched Synonyms: … PLUS HUMAN MINI-DYSTROPHIN GENE PLUS ADENO-ASSOCIATED VIRUS 9 INVERTED TERMINAL REPEAT FLANKS) ... DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 9 VECTOR PF-06939926 HUMAN MUSCLE-SPECIFIC ENHANCER/PROMOTER …
Displaying drugs 1876 - 1900 of 6223 in total