Displaying drugs 1901 - 1925 of 2327 in total
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Synonyms: … (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … α-phenyl-2-piperidineacetic acid methyl ester …
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Synonyms: … Citric acid, trisodium salt …
Matched Description: … It works by neutralizing excess acid in the blood and urine. ... Like citric acid, it has a sour taste. ... Sodium citrate is the sodium salt of citric acid. …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Antacids and Adsorbents ... Tricarboxylic Acids ... Citric Acid Derivatives …
Matched Description: … It works by neutralizing excess acid in the blood and urine. ... Like citric acid, it has a sour taste. ... Sodium citrate is the sodium salt of citric acid. …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Antacids and Adsorbents ... Tricarboxylic Acids ... Citric Acid Derivatives …
Tobevibart
Tobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).
Investigational
Matched Synonyms: … Immunoglobulin G1 [238-alanine,332-leucine,334-glutamic acid,430-leucine,436-serine], anti-(hepatitis …
Simvastatin
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). ... studies to significantly reduce the risk of development of CVD and all-cause mortality. …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril ... simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). ... studies to significantly reduce the risk of development of CVD and all-cause mortality. …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril ... simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate …
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid ... Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. ... product with cilastatin and [relebactam] which was recently approved by the FDA. ... semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Iupac: … aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. ... product with cilastatin and [relebactam] which was recently approved by the FDA. ... semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester
Experimental
Matched Name: … 7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester …
3-[(2,4-Dichlorobenzoyl)(Isopropyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid
Experimental
Matched Name: … 3-[(2,4-Dichlorobenzoyl)(Isopropyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid …
Matched Iupac: … 5-phenyl-3-[N-(propan-2-yl)2,4-dichlorobenzamido]thiophene-2-carboxylic acid …
Matched Iupac: … 5-phenyl-3-[N-(propan-2-yl)2,4-dichlorobenzamido]thiophene-2-carboxylic acid …
(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid
Experimental
Matched Name: … (2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid …
Matched Iupac: … (2S)-3-{[(9H-fluoren-9-ylidene)amino]oxy}-2-methylpropanoic acid …
Matched Iupac: … (2S)-3-{[(9H-fluoren-9-ylidene)amino]oxy}-2-methylpropanoic acid …
5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOPROPYL-HEXANOIC ACID
Experimental
Matched Name: … 5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOPROPYL-HEXANOIC ACID …
Matched Iupac: … (2S,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-(propan-2-yl)hexanoic acid …
Matched Iupac: … (2S,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-(propan-2-yl)hexanoic acid …
3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER
Experimental
Matched Name: … 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER …
3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID
Experimental
Matched Name: … 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID …
Matched Iupac: … 3-ethyl-6-(4-fluorobenzenesulfonamido)-2-methylbenzoic acid …
Matched Iupac: … 3-ethyl-6-(4-fluorobenzenesulfonamido)-2-methylbenzoic acid …
5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
Experimental
Matched Name: … 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
Experimental
Matched Name: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
Matched Iupac: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
Matched Iupac: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid …
6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID
Experimental
Matched Name: … 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID …
Matched Iupac: … 6-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}hexanoic acid …
Matched Iupac: … 6-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}hexanoic acid …
(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID
Experimental
Matched Name: … (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID …
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid …
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid …
Fenofibrate
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591]
Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Mixtures name: … ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MG …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... Acids, Acyclic ... pravastatin, ezetimibe and fenofibrate …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Mixtures name: … ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MG …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... Acids, Acyclic ... pravastatin, ezetimibe and fenofibrate …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … )-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … 2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Iupac: … 2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Moricizine
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester …
Cefmetazole
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Synonyms: … [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and ... It has a high rate of efficacy in many types of infection and to date no severe side effects have been …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and ... It has a high rate of efficacy in many types of infection and to date no severe side effects have been …
Cefonicid
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Approved
Investigational
Matched Synonyms: … [1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … sulfomethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone …
Matched Iupac: … sulfomethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone …
Doxazosin
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched Description: … [A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] ... Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. ... Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones …
Matched Products: … DOXAZOSIN ACINO 4MG …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones …
Matched Products: … DOXAZOSIN ACINO 4MG …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1901 - 1925 of 2327 in total