Displaying drugs 1976 - 2000 of 2922 in total
Genistein
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines.
Additionally, genistein has antihelmintic activity. It has been...
Investigational
Matched Mixtures name: … CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADET ... CALCİDAY G 1000 MG/880 IU/50 MG EFERVESAN TABLET, 40 ADET …
NGN-101
NGN-101 is an adeno-associated virus serotype 9 vector with engineered transgene encoding the human CLN5 gene
Investigational
Matched Description: … NGN-101 is an adeno-associated virus serotype 9 vector with engineered transgene encoding the human CLN5 …
Olokizumab
Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational
Odanacatib
Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis . The drug made it to phase III trials before abandoned due to increased stroke.
Investigational
T-900607
T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
Investigational
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Salts cas: … 13870-80-9 …
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... VAMIN 9 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML …
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... VAMIN 9 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML …
Alanine
Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Nutraceutical
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... VAMIN 9 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML …
Arginine
An essential amino acid that is physiologically active in the L-form.
Investigational
Nutraceutical
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... VAMIN 9 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML …
GT-AS
GT-AS recombinant adeno-associated virus serotype 9 vector containing the transgene UBE3A encoding for ubiquitin protein ligase E3A/E6-AP.
Investigational
Matched Description: … GT-AS recombinant adeno-associated virus serotype 9 vector containing the transgene UBE3A encoding for …
BNT162b1 SARS-CoV-2 Vaccine
BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Description: … a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding immunoglobulin levels and 50% …
Cinitapride
Cinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Investigational
Isoflavone
Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Description: … glycosylated forms and include [DB01645], [DB13182], and glycitein, which accounts for approximately 50% …
TSHA-105
TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.
Investigational
Matched Description: … TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding …
9r,13r-Opda
Experimental
PR006
PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene. It is being investigated for the treatment of dementia.
Investigational
Matched Description: … PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene …
ACTX-401
ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
Investigational
Matched Description: … ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing …
BMS-986020
BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers).
Investigational
Dexloxiglumide
Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist in phase III testing by Rottapharm in Europe only, as U.S. trials have been discontinued. As the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more potent.
Investigational
ATA-100
ATA-100 is an adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target sequence of the miR-208a
Investigational
Matched Description: … ATA-100 is an adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target …
GS-100
GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence
Investigational
Matched Description: … GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression …
MDX-210
Investigational
Rauwolfia serpentina root
Rauwolfia (Rauwolfia serpentina), also spelled ravolphia, is a medicinal plant in the milkweed family. The root of the plant is ground into a powder or sold in tablets or capsules. It is a compound commonly used in Asian medicine, which includes traditional Ayurvedic medicine native to India. The active ingredients...
Investigational
Matched Description: … The active ingredients in this drug are alkaloids and about 50 have been identified through various studies …
JLK-247
JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.
Investigational
Matched Description: … JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the …
Etrolizumab
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some...
Investigational
Displaying drugs 1976 - 2000 of 2922 in total