Displaying drugs 1976 - 2000 of 3611 in total
Porphobilinogen
Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Experimental
Matched Synonyms: … 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid …
Matched Iupac: … 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid …
Matched Description: … It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme …
Matched Iupac: … 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid …
Matched Description: … It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme …
3-deoxy-D-arabino-hexonic acid
Experimental
Matched Synonyms: … 3-Deoxy-arabino-hexonic acid …
Matched Name: … 3-deoxy-D-arabino-hexonic acid …
Matched Iupac: … (2S,4S,5R)-2,4,5,6-tetrahydroxyhexanoic acid …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … 3-deoxy-D-arabino-hexonic acid …
Matched Iupac: … (2S,4S,5R)-2,4,5,6-tetrahydroxyhexanoic acid …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
humanized SMART Anti-IL-12 Antibody
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized ... with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc. …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized ... with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc. …
(S)-DES-ME-AMPA
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …
Cytidine 3'-monophosphate
Experimental
Matched Synonyms: … 3'-Cytidylic acid …
Matched Iupac: … )-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … )-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Ataluren
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …
Nafamostat
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Synonyms: … p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine …
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome ... Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome ... Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …
Ferrous ascorbate
Approved
Matched Synonyms: … L-Ascorbic acid, iron complex …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
BGA002
Investigational
Matched Synonyms: … 16 base single stranded peptide nucleic acid oligonucleotide - 7 aminoacids peptide …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... ptosis, feeding difficulties) which may progress to more serious symptoms such as respiratory arrest and …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... ptosis, feeding difficulties) which may progress to more serious symptoms such as respiratory arrest and …
Matched Categories: … Human Immunoglobulin G …
Mebendazole
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Synonyms: … (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … GAMAX TABLETAS ... GAMAX SUSPENSIÓN …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … GAMAX TABLETAS ... GAMAX SUSPENSIÓN …
Cholecystokinin
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood Proteins ... Blood Coagulation Factors …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood Proteins ... Blood Coagulation Factors …
Clofibrate
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester ... alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester ... 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Acids, Acyclic ... Clofibric Acid ... Carboxylic Acids ... Fibric Acids …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Acids, Acyclic ... Clofibric Acid ... Carboxylic Acids ... Fibric Acids …
(R)-etodolac
Investigational
Matched Synonyms: … (1r)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1r)- ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (r)- …
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
Matched Synonyms: … Phosphoric acid, 2,2-dichlorovinyl dimethyl ester ... Phosphoric acid, 2,2-dichloroethenyl dimethyl ester …
Matched Description: … Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity ... , and cancer. ... environmental and health concerns. …
Matched Description: … Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity ... , and cancer. ... environmental and health concerns. …
Bromotheophylline
Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline …
Matched Products: … Midol Bloat Relief …
Matched Products: … Midol Bloat Relief …
Dalteparin
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … 5000 and about 90% of the material within the range of 2000-9000. ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than ... Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated …
Matched Salts name: … Dalteparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … DALTEPARINA SODICA INYECCIÒN 5000 UI ... DALTEPARINA SODICA 2500 UI INYECCION …
Matched Salts name: … Dalteparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … DALTEPARINA SODICA INYECCIÒN 5000 UI ... DALTEPARINA SODICA 2500 UI INYECCION …
Pociredir
Investigational
Matched Synonyms: … 7h-furo(4,3,2-gh)(1,2,4)triazolo(4',3':1,6)pyrido(2,3-c)(5,2)benzoxazonine, 12-fluoro-7a,8,13,14-tetrahydro …
Matched Iupac: … methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9}.0^{18,22}]docosa-1(22),4(12 …
Matched Iupac: … methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9}.0^{18,22}]docosa-1(22),4(12 …
Valaciclovir
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Salts name: … Valaciclovir hydrochloride monohydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Amino Acids …
Matched Products: … VALACICLOVIR HCL MONOHYDRATE …
Matched Salts name: … Valaciclovir hydrochloride monohydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Amino Acids …
Matched Products: … VALACICLOVIR HCL MONOHYDRATE …
Efocipegtrutide
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- ... GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Factor XIII (human)
Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Synonyms: … Factor XIII, human ... Human coagulation factor XIII ... Factor XIII concentrate (human) …
Matched Name: … Factor XIII (human) …
Matched Description: … This contributes to enhanced platelet and clot adhesion to injured tissue, thereby improving blood coagulation ... Other drug products with similar structure and function to Factor XIII (human) include [DB09310], which ... the final enzyme within the blood coagulation cascade. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood Proteins ... Blood Coagulation Factors …
Matched Products: … Corifact 1250 ... Fibrogammin 1250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …
Matched Name: … Factor XIII (human) …
Matched Description: … This contributes to enhanced platelet and clot adhesion to injured tissue, thereby improving blood coagulation ... Other drug products with similar structure and function to Factor XIII (human) include [DB09310], which ... the final enzyme within the blood coagulation cascade. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood Proteins ... Blood Coagulation Factors …
Matched Products: … Corifact 1250 ... Fibrogammin 1250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …
Recombinant human galactocerebrosidase
Investigational
Matched Synonyms: … Recombinant human galactocerebrosidase …
Matched Name: … Recombinant human galactocerebrosidase …
Matched Name: … Recombinant human galactocerebrosidase …
THR-184
THR-184 is under investigation in clinical trial NCT01830920 (A Study of THR-184 in Patients at Risk of Developing Cardiac Surgery Associated-acute Kidney Injury (CSA-AKI)).
Investigational
Matched Synonyms: … -ASPARTYL-L-ASPARAGINYL-L-SERYL-L-SERYL-L-SERYL-L-VALYL-L-LEUCYL-L-CYSTEINYL-L-LYSYL-L-ARGINYL-L-TYROSYL-L-ARGINYL-L-SERINE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1976 - 2000 of 3611 in total