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Displaying drugs 2026 - 2050 of 2844 in total
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
A combination of docosahexaenoic Acid (a natural fatty acid) and paclitaxel (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.
Investigational
Investigational
Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).
Investigational
Experimental
Matched Iupac: … 8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-3-one …
Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Investigational
Experimental
Matched Iupac: … sodium 8-hydroxy-7-iodoquinoline-5-sulfonic acid hydrogen carbonate …
Experimental
Matched Iupac: … 3-phenyl-7-(propan-2-yloxy)-4H-chromen-4-one …
Experimental
Matched Iupac: … 7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Experimental
Matched Iupac: … 4-(7-bromo-5-methoxy-1-benzofuran-2-yl)piperidine …
An anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Withdrawn
Matched Iupac: … 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate …
Prinaberel is an estrogen receptor beta agonist.
Investigational
Matched Iupac: … 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol …
Equol has been used in trials studying the treatment of Breast Cancer.
Investigational
Matched Iupac: … (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol …
Experimental
Investigational
Matched Iupac: … bis(7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo …
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some...
Investigational
Investigational
Displaying drugs 2026 - 2050 of 2844 in total