Displaying drugs 2051 - 2075 of 2793 in total
DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID
Experimental
Matched Name: … DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID …
5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID
Experimental
Matched Name: … 5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID …
Matched Iupac: … 5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid …
Matched Iupac: … 5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid …
(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid …
4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID
Experimental
Matched Name: … 4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Experimental
Matched Name: … 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID …
Matched Iupac: … 1-phenyl-1H-pyrazole-4-carboxylic acid …
Matched Iupac: … 1-phenyl-1H-pyrazole-4-carboxylic acid …
Eluxadoline
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Guaiacol
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Gemfibrozil
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Rodatristat
Investigational
Matched Synonyms: … chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid ... 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
Cilastatin
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid …
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
BMS-986278
Investigational
Matched Synonyms: … methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
6-hydroxydopa quinone
Experimental
Matched Synonyms: … Topa quinone ... (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … from baseline with more than 70% of patients failing to achieve an absolute improvement of at least ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change …
Matched Categories: … ivacaftor and lumacaftor …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … from baseline with more than 70% of patients failing to achieve an absolute improvement of at least ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change …
Matched Categories: … ivacaftor and lumacaftor …
4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid
Experimental
Matched Name: … 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
[[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid,
Experimental
Matched Name: … [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid, …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid …
alpha-D-glucopyranosyl-2-carboxylic acid amide
Experimental
Matched Name: … alpha-D-glucopyranosyl-2-carboxylic acid amide …
(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid
Experimental
Matched Name: … (3-Chloro-4-Propoxy-Phenyl)-Acetic Acid …
Matched Iupac: … 2-(3-chloro-4-propoxyphenyl)acetic acid …
Matched Iupac: … 2-(3-chloro-4-propoxyphenyl)acetic acid …
(3-Formyl-but-3-Enyl)-Phosphonic Acid
Experimental
Matched Name: … (3-Formyl-but-3-Enyl)-Phosphonic Acid …
Matched Iupac: … (3-methylidene-4-oxobutyl)phosphonic acid …
Matched Iupac: … (3-methylidene-4-oxobutyl)phosphonic acid …
1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide
Experimental
Matched Name: … 1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide …
2-deoxy-2,3-dehydro-N-acetylneuraminic acid
Experimental
Matched Name: … 2-deoxy-2,3-dehydro-N-acetylneuraminic acid …
Matched Iupac: … 2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Sialic Acids ... Carboxylic Acids …
Matched Iupac: … 2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Sialic Acids ... Carboxylic Acids …
4-O-methyl-alpha-D-glucuronic acid
Experimental
Matched Name: … 4-O-methyl-alpha-D-glucuronic acid …
Matched Iupac: … (2S,3S,4R,5R,6S)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,3S,4R,5R,6S)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME)
Experimental
Matched Name: … DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME) …
(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
Experimental
Matched Name: … (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) …
Matched Iupac: … (1-hydroxy-1-phosphonoheptyl)phosphonic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoheptyl)phosphonic acid …
(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
Experimental
Matched Name: … (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) …
Matched Iupac: … (1-hydroxy-1-phosphonononyl)phosphonic acid …
Matched Iupac: … (1-hydroxy-1-phosphonononyl)phosphonic acid …
Displaying drugs 2051 - 2075 of 2793 in total