Search Results | DrugBank Online

Displaying drugs 2051 - 2075 of 15829 in total

Cinnamaldehyde

Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.

Approved

Experimental

Matched Description: … and cassia. ... Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour ... It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor …
Matched Categories: … Cell-mediated Immunity ... Diet, Food, and Nutrition …

Oxandrolone

A synthetic hormone with anabolic and androgenic properties.

Approved

Investigational

Matched Description: … A synthetic hormone with anabolic and androgenic properties. …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Polydatin

Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...

Approved

Matched Description: … It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis ... Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …

Troleandomycin

A macrolide antibiotic that is similar to erythromycin.

Approved

Matched Categories: … Macrolides, Lincosamides and Streptogramins …

Pergolide

Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....

Approved

Investigational

Vet approved

Withdrawn

Matched Iupac: … (2R,4R,7R)-4-[(methylsulfanyl)methyl]-6-propyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca- …
Matched Description: … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine ... The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. …
Matched Categories: … Ergot Alkaloids and Derivatives …

Amivantamab

Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose...

Approved

Investigational

Matched Description: … ovary cells, approved for the treatment of adult patients with locally advanced or metastatic non-small cell ... FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and ... [A235103,L34193] Patients with NSCLC often develop resistance to drugs that target EGFR and MET individually …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Gemcitabine

Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...

Approved

Matched Description: … combination with [carboplatin], metastatic breast cancer in combination with [paclitaxel], non-small cell ... Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [L32950] It is also being investigated in other cancer and tumour types. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …

Cavia porcellus skin

Cavia porcellus skin or pelt is used in allergenic testing.

Approved

Matched Mixtures name: … Guinea Pig Hair and Epithelia …
Matched Categories: … Cell-mediated Immunity …

Tetraferric tricitrate decahydrate

Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.

Approved

Matched Description: … Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and …
Matched Mixtures name: … Maxine Vitamin and Mineral Supplement …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Cevimeline

Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.

Approved

Matched Iupac: … (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] …
Matched Description: … is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's …

Stavudine

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Approved

Investigational

Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... stavudine and lamivudine ... stavudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Sus scrofa hair

Wild boar hair is used in allergenic testing.

Approved

Matched Mixtures name: … Hog Hair and Epithelia …
Matched Categories: … Cell-mediated Immunity …

Salix alba bark

Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Approved

Experimental

Matched Mixtures name: … Herbal Cold and Flu Formula - Tab …
Matched Categories: … Herbs and Natural Products …

Oryctolagus cuniculus hair

European rabbit hair is used in allergenic testing.

Approved

Matched Mixtures name: … Rabbit Hair and Epithelia …
Matched Categories: … Cell-mediated Immunity …

Repotrectinib

Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...

Approved

Investigational

Matched Description: … tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell ... [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and …

Relatlimab

Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...

Approved

Investigational

Matched Description: … Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte ... was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013,[A246155] and ... has garnered interest in the treatment of a variety of cancers, including leukemia[A246160] and melanoma …
Matched Categories: … nivolumab and relatlimab ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Zea mays pollen

Zea mays pollen is the pollen of the Zea mays plant. Zea mays pollen is mainly used in allergenic testing.

Approved

Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Categories: … Cell-mediated Immunity …

Elymus repens pollen

Elymus repens pollen is the pollen of the Elymus repens plant. Elymus repens pollen is mainly used in allergenic testing.

Approved

Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Categories: … Cell-mediated Immunity …

Clostridium tetani

Approved

Matched Mixtures name: … Tetanus and Diphtheria Toxoids Adsorbed …

Fraxinus americana pollen

Fraxinus americana pollen is the pollen of the Fraxinus americana plant. Fraxinus americana pollen is mainly used in allergenic testing.

Approved