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Displaying drugs 2101 - 2125 of 6795 in total
Quinalizarin
Experimental
2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
Experimental
Matched Name: … 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one …
Matched Iupac: … 2-methyl-3H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one …
Matched Iupac: … 2-methyl-3H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one …
1D-myo-inositol 1,4,5-trisphosphate
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity...
Experimental
Matched Description: … Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate …
Rivanicline
Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. It has subsequently been developed...
Investigational
Matched Synonyms: … (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine ... (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine ... N-methyl-4-(3-pyridinyl)-(3E)-3-buten-1-amine …
Matched Iupac: … methyl[(3E)-4-(pyridin-3-yl)but-3-en-1-yl]amine …
Matched Description: … disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. …
Matched Iupac: … methyl[(3E)-4-(pyridin-3-yl)but-3-en-1-yl]amine …
Matched Description: … disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. …
1-Amino-6-Cyclohex-3-Enylmethyloxypurine
Experimental
Matched Iupac: … 4-(cyclohexylmethoxy)-1H-imidazo[4,5-c]pyridin-6-amine …
GSK-690693
GSK690693 has been used in trials studying the treatment of Tumor, CANCER, and Lymphoma.
Investigational
Matched Iupac: … 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-piperidin-3-yl]methoxy}-1H-imidazo[4,5-c]pyridin ... -4-yl]-2-methylbut-3-yn-2-ol …
NNZ-2591
NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and...
Investigational
Pociredir
Investigational
Matched Synonyms: … -4-(2-methyl-3-pyridinyl)-, (7as)- ... 7h-furo(4,3,2-gh)(1,2,4)triazolo(4',3':1,6)pyrido(2,3-c)(5,2)benzoxazonine, 12-fluoro-7a,8,13,14-tetrahydro …
Matched Iupac: … methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9}.0^{18,22}]docosa-1(22),4( …
Matched Iupac: … methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9}.0^{18,22}]docosa-1(22),4( …
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Iupac: … 5-(2-chloroethyl)-4-methyl-1,3-thiazole …
Iluzanebart
Investigational
INS018_055
Investigational
Matched Synonyms: … 5’-(4-fluorophenyl)-3’-isopropyl-N-(4-(4-methylpiperazin-1-yl)phenyl)-1H,3’H-[2,4’-biimidazole]-4-carboxamide …
Matched Iupac: … 5'-(4-fluorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-3'-(propan-2-yl)-3H,3'H-[2,4'-biimidazole]-4 …
Matched Iupac: … 5'-(4-fluorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-3'-(propan-2-yl)-3H,3'H-[2,4'-biimidazole]-4 …
LM-030
Investigational
Matched Synonyms: … )-21-HYDROXY-5-(4-HYDROXY-BENZYL)-15-ISOBUTYL-4,11-DIMETHYL-3,6,9,13,16,22-HEXAOXO-10-OXA-1,4,7,14,17 ... (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL …
Matched Iupac: … (2S)-N-[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-bis[(2S)-butan-2-yl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl …
Matched Iupac: … (2S)-N-[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-bis[(2S)-butan-2-yl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl …
4'-Methylene-5,8,10-trideazaaminopterin
CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier (RFC) system than is Methotrexate. It has been investigated for the treatment of Rheumatoid Arthritis (phase II).
Investigational
Matched Name: … 4'-Methylene-5,8,10-trideazaaminopterin …
Matched Iupac: … 2-({4-[2-(2,4-diaminoquinazolin-6-yl)ethyl]phenyl}formamido)-4-methylidenepentanedioic acid …
Matched Iupac: … 2-({4-[2-(2,4-diaminoquinazolin-6-yl)ethyl]phenyl}formamido)-4-methylidenepentanedioic acid …
5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
Experimental
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid
Experimental
Matched Name: … 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic …
Matched Iupac: … 3-fluoro-4-[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido]benzoic …
Matched Iupac: … 3-fluoro-4-[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido]benzoic …
Diazepinomicin
Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. Diazepinomicin is a natural product derived from a non-pathogenic micro-organism. Discovered using Thallion’s DECIPHER...
Investigational
Alagebrium
Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Iupac: … 4,5-dimethyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium …
AAV-CNGB3
AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Investigational
Matched Description: … AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene. …
Ruplizumab
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
Experimental
Matched Name: … (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid …
Matched Iupac: … (1S,3aS,3bS,9aR,9bS,11aS)-1-(4-hydroxybenzoyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H, …
Matched Iupac: … (1S,3aS,3bS,9aR,9bS,11aS)-1-(4-hydroxybenzoyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H, …
Triciribine phosphate
Investigational
Matched Synonyms: … 3-AMINO-1,5-DIHYDRO-5-METHYL-1-.BETA. ... Pentaazaacenaphthylene-5' phosphate ester ... -D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE) …
Matched Iupac: … {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Iupac: … {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Icaritin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
4-Methyl-5-Hydroxyethylthiazole Phosphate
Experimental
Matched Name: … 4-Methyl-5-Hydroxyethylthiazole Phosphate …
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
Crozbaciclib
Investigational
Matched Synonyms: … 5-fluoro-4-(7'-fluoro-2'-methylspiro[cyclopentane-1,3'- indol]-5'-yl)-N-[5-(1-methylpiperidin-4-yl)pyridin ... 2-PYRIMIDINAMINE, 5-FLUORO-4-(7'-FLUORO-2'-METHYLSPIRO(CYCLOPENTANE-1,3'-(3H)INDOL)-5'-YL)-N-(5-(1-METHYL ... -4-PIPERIDINYL)-2-PYRIDINYL)- …
Matched Iupac: … 5-fluoro-4-{7'-fluoro-2'-methylspiro[cyclopentane-1,3'-indol]-5'-yl}-N-[5-(1-methylpiperidin-4-yl)pyridin …
Matched Iupac: … 5-fluoro-4-{7'-fluoro-2'-methylspiro[cyclopentane-1,3'-indol]-5'-yl}-N-[5-(1-methylpiperidin-4-yl)pyridin …
Carboxyamidotriazole
Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Investigational
Matched Iupac: … 5-amino-1-{[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide …
Displaying drugs 2101 - 2125 of 6795 in total