Displaying drugs 2176 - 2200 of 2901 in total
Guaiacol
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Gemfibrozil
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not ... responded adequately to weight loss, diet, exercise, and other medications. …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not ... responded adequately to weight loss, diet, exercise, and other medications. …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Cilastatin
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid …
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
BMS-986278
Investigational
Matched Synonyms: … methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE
Experimental
Matched Name: … 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE …
Daglutril
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetic acid …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
PTX-100
Investigational
Matched Synonyms: … 2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
6-hydroxydopa quinone
Experimental
Matched Synonyms: … (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion channel involved in the transport of chloride ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... and sodium ions across cell membranes of the lungs, pancreas, and other organs. …
Matched Categories: … ivacaftor and lumacaftor …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion channel involved in the transport of chloride ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... and sodium ions across cell membranes of the lungs, pancreas, and other organs. …
Matched Categories: … ivacaftor and lumacaftor …
Cloxacillin
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
JS-K
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-((2,4-dinitrophenoxy)-nno-azoxy)-, ethyl ester ... 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester …
4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid
Experimental
Matched Name: … 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
[[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid,
Experimental
Matched Name: … [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid, …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid …
Matched Iupac: … {[4-(aminomethyl)phenyl]carbamoyl}formic acid …
alpha-D-glucopyranosyl-2-carboxylic acid amide
Experimental
Matched Name: … alpha-D-glucopyranosyl-2-carboxylic acid amide …
(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid
Experimental
Matched Name: … (3-Chloro-4-Propoxy-Phenyl)-Acetic Acid …
Matched Iupac: … 2-(3-chloro-4-propoxyphenyl)acetic acid …
Matched Iupac: … 2-(3-chloro-4-propoxyphenyl)acetic acid …
(3-Formyl-but-3-Enyl)-Phosphonic Acid
Experimental
Matched Name: … (3-Formyl-but-3-Enyl)-Phosphonic Acid …
Matched Iupac: … (3-methylidene-4-oxobutyl)phosphonic acid …
Matched Iupac: … (3-methylidene-4-oxobutyl)phosphonic acid …
1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide
Experimental
Matched Name: … 1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide …
2-deoxy-2,3-dehydro-N-acetylneuraminic acid
Experimental
Matched Name: … 2-deoxy-2,3-dehydro-N-acetylneuraminic acid …
Matched Iupac: … 2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Sialic Acids ... Carboxylic Acids …
Matched Iupac: … 2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Sialic Acids ... Carboxylic Acids …
4-O-methyl-alpha-D-glucuronic acid
Experimental
Matched Name: … 4-O-methyl-alpha-D-glucuronic acid …
Matched Iupac: … (2S,3S,4R,5R,6S)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,3S,4R,5R,6S)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME)
Experimental
Matched Name: … DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME) …
(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
Experimental
Matched Name: … (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) …
Matched Iupac: … (1-hydroxy-1-phosphonoheptyl)phosphonic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoheptyl)phosphonic acid …
(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
Experimental
Matched Name: … (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) …
Matched Iupac: … (1-hydroxy-1-phosphonononyl)phosphonic acid …
Matched Iupac: … (1-hydroxy-1-phosphonononyl)phosphonic acid …
4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
Experimental
Matched Name: … 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID …
Matched Iupac: … 4'-fluoro-[1,1'-biphenyl]-4-carboxylic acid …
Matched Iupac: … 4'-fluoro-[1,1'-biphenyl]-4-carboxylic acid …
2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID
Experimental
Matched Name: … 2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID …
Matched Iupac: … 2-[2-(4-chlorophenoxy)acetamido]benzoic acid …
Matched Iupac: … 2-[2-(4-chlorophenoxy)acetamido]benzoic acid …
Displaying drugs 2176 - 2200 of 2901 in total