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Displaying drugs 201 - 225 of 10683 in total
Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as sunitinib and imatinib. Ripretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020....
Approved
Matched Iupac: … 1-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-3-phenylurea …
Matched Description: … [L13769] It is the first drug approved as a fourth-line therapy in the specific setting of prior ... treatment with a minimum of 3 other kinase inhibitors. ... Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST …
Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049
Approved
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-[(2R)-butan-2-yl]-2-hydroxy-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … -13'-epi-b-ergocryptine. ... Epicriptine differs from the alpha form on the position of one methyl group. ... Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … in dogs. ... [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … BONVIVA 3MG/3ML ILO IN FER ... OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe ... Ibandronsäure ratiopharm 3 mg Injektionslösung in einer Fertigspritze …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Products: … Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Lemocin Flurbiprofen 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... the virus) which results in an immunological defense against future exposure to the virus, or "antigen …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Description: … HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the ... has resulted in this class becoming one of the most widely prescribed medications in North America. ... in potency, there was no difference in their effect on the progression of coronary atherosclerosis. …
Matched Categories: … Drugs Used in Diabetes ... combinations of sulfonamides …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009(H1N1)-like hemagglutinin antigen (propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 X-181 (H1N1) hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … FluVaccinol Subunit Tetra Injektionssuspension in einer Fertigspritze …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) hemagglutinin antigen (UV, formaldehyde inactivated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … It usually results in a bowel movement after 30 minutes to 6 hours. ... Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … NUTRIFLEX PLUS IN 1000ML TWIN FLEX ... NUTRIFLEX PLUS IN 2000ML TWIN FLEX ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Categories: … Drugs for Treatment of Hypercalcemia …
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... However, it continues to be used in the treatment of Brugada syndrome, short QT syndrome and idiopathic ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Compounds used in a research, industrial, or household setting …
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide …
Matched Description: … [L4810] Some evidence in the literature suggests the therapeutic potential of dacomitinib in the epithelial ... designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of ... second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … between 5% and 50% of the general population. ... Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect ... Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. …
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Description: … [L48902] It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating ... SARS-CoV-2 subvariants in 2023. ... [L48902,L48907] Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Iupac: … 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan …
Matched Description: … [L39640] Remdesivir in combination with [baricitinib] for the treatment of COVID-19, was granted an FDA ... in 2016 as a potential treatment for Ebola. ... [A191379, A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action,[A222398 …
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of ... Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease. ... Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. …
Propolis wax is naturally produced by honeybees by mixing the resin or exudate collected from tree buds, sap flows, or other botanical sources with beeswax that contains fatty acids and bee enzymes. Propolis itself contains various chemical compounds including flavonoids, terpenoids, aldehydes, aromatic acids, aliphatic alcohols and ethers, amino acids,...
Approved
Matched Description: … It is often found in topical formulations used to soothe minor skin irritations. …
Matched Mixtures name: … Dr.bro MAN OF SENSE Mans Cleanser …
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic disorder in which ... patisiran]), a new class of drugs promising an important and exciting step forward in the treatment of ... [L10202] Givosiran represents an important step forward in the treatment of acute hepatic porphyria as …
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Mixture of Standardized Mites ... Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml) ... Allergenic Extract Mixture Of Standardized Mites (15,000 Au/ml) …
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of
Matched Mixtures name: … Mega 13 Multivitamin Formula ... Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Matched Products: … Formula # 7 Tab 50mg …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... [L12078] Interferon-beta has been used in the past in clinical studies with other coronaviruses due to ... (MS), and was initially approved by the FDA in 1992. …
Sage allergenic extract is used in allergenic testing.
Approved
Matched Description: … Sage allergenic extract is used in allergenic testing. …
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … are synthetic structural analogs of prostaglandin. ... Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. …
Displaying drugs 201 - 225 of 10683 in total