Displaying drugs 2301 - 2325 of 3666 in total
Metrifonate
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Lesinurad
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... levels with a xanthine oxidase inhibitor alone. …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... levels with a xanthine oxidase inhibitor alone. …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Candoxatril
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with …
Matched Categories: … beta-Lactams ... Thiazines …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with …
Matched Categories: … beta-Lactams ... Thiazines …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Beta-D-Glucopyranose Spirohydantoin
Experimental
Matched Name: … Beta-D-Glucopyranose Spirohydantoin …
beta-(1->4)-galactotriose
Experimental
Matched Synonyms: … beta-1,4-galactotrioside …
Matched Name: … beta-(1->4)-galactotriose …
Matched Name: … beta-(1->4)-galactotriose …
ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE
Experimental
Matched Name: … ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Monoamine Oxidase A Substrates ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
Matched Mixtures name: … Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Monoamine Oxidase A Substrates ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
3,6-dihydroxy-xanthene-9-propionic acid
Experimental
Matched Name: … 3,6-dihydroxy-xanthene-9-propionic acid …
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid …
Matched Iupac: … 3-(3,6-dihydroxy-9H-xanthen-9-yl)propanoic acid …
(5r)-5-Amino-6-Hydroxyhexylcarbamic Acid
Experimental
Matched Name: … (5r)-5-Amino-6-Hydroxyhexylcarbamic Acid …
Matched Iupac: … [(5S)-5-amino-6-hydroxyhexyl]carbamic acid …
Matched Iupac: … [(5S)-5-amino-6-hydroxyhexyl]carbamic acid …
4-(Carboxyvin-2-Yl)Phenylboronic Acid
Experimental
Matched Name: … 4-(Carboxyvin-2-Yl)Phenylboronic Acid …
Matched Iupac: … (2E)-3-[4-(dihydroxyboranyl)phenyl]prop-2-enoic acid …
Matched Iupac: … (2E)-3-[4-(dihydroxyboranyl)phenyl]prop-2-enoic acid …
3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
Experimental
Matched Name: … 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid …
Matched Iupac: … 3-(1,3-benzothiazol-2-ylsulfanyl)propane-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids …
Matched Iupac: … 3-(1,3-benzothiazol-2-ylsulfanyl)propane-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids …
6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid
Experimental
Matched Name: … 6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid …
Matched Iupac: … (6S)-8-[(aminomethyl)sulfanyl]-6-[(2-hydroxyethyl)disulfanyl]octanoic acid …
Matched Iupac: … (6S)-8-[(aminomethyl)sulfanyl]-6-[(2-hydroxyethyl)disulfanyl]octanoic acid …
7-(Carboxyamino)-8-Amino-Nonanoic Acid
Experimental
Matched Name: … 7-(Carboxyamino)-8-Amino-Nonanoic Acid …
Matched Iupac: … (7R,8S)-8-amino-7-(carboxyamino)nonanoic acid …
Matched Iupac: … (7R,8S)-8-amino-7-(carboxyamino)nonanoic acid …
1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
Experimental
Matched Name: … 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid …
Matched Iupac: … (2R,3R,4S,5R,6S)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …
Matched Iupac: … (2R,3R,4S,5R,6S)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …
(10R)-10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Name: … (10R)-10-formyl-5,8,10-trideazafolic acid …
Matched Iupac: … ({4-[(1R)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic acid …
Matched Iupac: … ({4-[(1R)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic acid …
Benzo[B]Thiophene-2-Boronic Acid
Experimental
Matched Name: … Benzo[B]Thiophene-2-Boronic Acid …
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid …
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid …
(2R)-2-benzyl-3-nitropropanoic acid
Experimental
Matched Name: … (2R)-2-benzyl-3-nitropropanoic acid …
Matched Iupac: … (2R)-2-benzyl-3-nitropropanoic acid …
Matched Iupac: … (2R)-2-benzyl-3-nitropropanoic acid …
Displaying drugs 2301 - 2325 of 3666 in total